1TWQ

Crystal structure of the C-terminal PGN-binding domain of human PGRP-Ialpha in complex with PGN analog muramyl tripeptide

Summary for 1TWQ

• Entry DOI: 10.2210/pdb1twq/pdb
• Related: 1SK3 1SK4
• Descriptor: peptidoglycan recognition protein-I-alpha, muramyl tripeptide, NICKEL (II) ION, ... (5 entities in total)
• Functional Keywords: crystal structure; complex; pgrp; pgrp-ialpha; pgn analog, immune system, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 18968.17

Authors

Guan, R.,Roychowdury, A.,Boons, G.-A.,Mariuzza, R.A. (deposition date: 2004-07-01, release date: 2004-12-14, Last modification date: 2024-02-28)

• Primary citation: Guan, R.,Roychowdhury, A.,Ember, B.,Kumar, S.,Boons, G.-A.,Mariuzza, R.A.; Structural basis for peptidoglycan binding by peptidoglycan recognition proteins; Proc.Natl.Acad.Sci.USA, 101:17168-17173, 2004; PubMed: 15572450; DOI: 10.1073/pnas.0407856101

Experimental method

X-RAY DIFFRACTION (2.3 Å)