4E42

Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4

Summary for 4E42

• Entry DOI: 10.2210/pdb4e42/pdb
• Related: 4E41
• Descriptor: T cell receptor G4 alpha chain, T cell receptor G4 beta chain, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: ig domain, adaptive immunity, t cell receptor, mhc, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 4
• Total formula weight: 100139.30

Authors

Deng, L.,Langley, R.J.,Wang, Q.,Topalian, S.L.,Mariuzza, R.A. (deposition date: 2012-03-11, release date: 2012-08-29, Last modification date: 2023-09-13)

• Primary citation: Deng, L.,Langley, R.J.,Wang, Q.,Topalian, S.L.,Mariuzza, R.A.; Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4; Proc.Natl.Acad.Sci.USA, 2012

Experimental method

X-RAY DIFFRACTION (2.7 Å)