4E41

Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4

Summary for 4E41

• Entry DOI: 10.2210/pdb4e41/pdb
• Related: 4E42
• Descriptor: HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1-1 beta chain, Triosephosphate isomerase, ... (7 entities in total)
• Functional Keywords: ig domain, adaptive immunity, t cell receptor, mhc, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Cell membrane; Single-pass type I membrane protein: P01903 P04229
• Total number of polymer chains: 10
• Total formula weight: 189132.78

Authors

Deng, L.,Langley, R.J.,Wang, Q.,Topalian, S.L.,Mariuzza, R.A. (deposition date: 2012-03-11, release date: 2012-08-29, Last modification date: 2023-09-13)

• Primary citation: Deng, L.,Langley, R.J.,Wang, Q.,Topalian, S.L.,Mariuzza, R.A.; Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4; Proc.Natl.Acad.Sci.USA, 2012

Experimental method

X-RAY DIFFRACTION (2.6 Å)