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PDB: 1323 件

6R1K
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Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 7c
分子名称: Cereblon isoform 4, PHOSPHATE ION, ZINC ION, ...
著者Heim, C, Hartmann, M.D.
登録日2019-03-14
公開日2019-08-07
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R1W
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Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 16b
分子名称: (4-azanylcyclohexyl)methyl ~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]carbamate, Cereblon isoform 4, PHOSPHATE ION, ...
著者Heim, C, Hartmann, M.D.
登録日2019-03-15
公開日2019-08-07
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R1C
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Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 12a
分子名称: 4-[[4-[[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]carbamoyloxymethyl]phenyl]methylamino]-4-oxidanylidene-butanoic acid, ASPARTIC ACID, CHLORIDE ION, ...
著者Heim, C, Hartmann, M.D.
登録日2019-03-14
公開日2019-08-07
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R60
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asymmetric antiparallel assembly of two 5-bladed beta-propeller fragments
分子名称: WD-40 repeat protein
著者Afanasieva, E, Lupas, A.N, Hartmann, M.D.
登録日2019-03-26
公開日2019-11-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural diversity of oligomeric beta-propellers with different numbers of identical blades.
Elife, 8, 2019
2XQH
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Crystal structure of an immunoglobulin-binding fragment of the trimeric autotransporter adhesin EibD
分子名称: CHLORIDE ION, IMMUNOGLOBULIN-BINDING PROTEIN EIBD
著者Leo, J.C, Lyskowski, A, Hartmann, M, Schwarz, H, Linke, D, Lupas, A.N, Goldman, A.
登録日2010-09-02
公開日2011-07-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献The Structure of E. Coli Igg-Binding Protein D Suggests a General Model for Bending and Binding in Trimeric Autotransporter Adhesins.
Structure, 19, 2011
2V8C
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Mouse Profilin IIa in complex with the proline-rich domain of VASP
分子名称: GLYCEROL, ISOPROPYL ALCOHOL, PROFILIN-2, ...
著者Kursula, P, Downer, J, Witke, W, Wilmanns, M.
登録日2007-08-06
公開日2007-12-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献High-Resolution Structural Analysis of Mammalian Profilin 2A Complex Formation with Two Physiological Ligands: The Formin Homology 1 Domain of Mdia1 and the Proline-Rich Domain of Vasp.
J.Mol.Biol., 375, 2008
3STJ
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BU of 3stj by Molmil
Crystal structure of the protease + PDZ1 domain of DegQ from Escherichia coli
分子名称: Protease degQ, peptide (UNK)
著者Sawa, J, Malet, H, Krojer, T, Canellas, F, Ehrmann, M, Clausen, T.
登録日2011-07-11
公開日2011-07-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope.
J.Biol.Chem., 286, 2011
4HAR
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Crystal Structure of Rubella virus capsid protein (residues 127-277)
分子名称: CHLORIDE ION, Capsid protein, LAURYL DIMETHYLAMINE-N-OXIDE
著者Mangala Prasad, V, Fokine, A, Rossmann, M.G.
登録日2012-09-27
公開日2013-12-11
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.663 Å)
主引用文献Rubella virus capsid protein structure and its role in virus assembly and infection.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HUD
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Structure of the bacteriophage T4 tail terminator protein, gp15.
分子名称: Tail connector protein Gp15
著者Fokine, A, Zhang, Z, Kanamaru, S, Bowman, V.D, Aksyuk, A, Arisaka, F, Rao, V.B, Rossmann, M.G.
登録日2012-11-02
公開日2013-02-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7001 Å)
主引用文献The molecular architecture of the bacteriophage t4 neck.
J.Mol.Biol., 425, 2013
3GVM
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Structure of the homodimeric WXG-100 family protein from Streptococcus agalactiae
分子名称: Putative uncharacterized protein SAG1039
著者Poulsen, C, Gries, F, Wilmanns, M, Song, Y.H.
登録日2009-03-31
公開日2010-09-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献WXG100 protein superfamily consists of three subfamilies and exhibits an alpha-helical C-terminal conserved residue pattern.
Plos One, 9, 2014
4C46
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ANDREI-N-LVPAS fused to GCN4 adaptors
分子名称: BROMIDE ION, GENERAL CONTROL PROTEIN GCN4
著者Albrecht, R, Alva, V, Ammelburg, M, Baer, K, Basina, E, Boichenko, I, Bonhoeffer, F, Braun, V, Chaubey, M, Chauhan, N, Chellamuthu, V.R, Coles, M, Deiss, S, Ewers, C.P, Forouzan, D, Fuchs, A, Groemping, Y, Hartmann, M.D, Hernandez Alvarez, B, Jeganantham, A, Kalev, I, Koenninger, U, Koiwai, K, Kopec, K.O, Korycinski, M, Laudenbach, B, Lehmann, K, Leo, J.C, Linke, D, Marialke, J, Martin, J, Mechelke, M, Michalik, M, Noll, A, Patzer, S.I, Scharfenberg, F, Schueckel, M, Shahid, S.A, Sulz, E, Ursinus, A, Wuertenberger, S, Zhu, H.
登録日2013-08-30
公開日2013-09-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Your Personalized Protein Structure: Andrei N. Lupas Fused to GCN4 Adaptors.
J.Struct.Biol., 186, 2014
1SOZ
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Crystal Structure of DegS protease in complex with an activating peptide
分子名称: Protease degS, activating peptide
著者Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T.
登録日2004-03-16
公開日2004-06-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease
Cell(Cambridge,Mass.), 117, 2004
1VCW
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Crystal structure of DegS after backsoaking the activating peptide
分子名称: Protease degS
著者Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T.
登録日2004-03-16
公開日2004-06-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease.
Cell(Cambridge,Mass.), 117, 2004
1CWW
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BU of 1cww by Molmil
SOLUTION STRUCTURE OF THE CASPASE RECRUITMENT DOMAIN (CARD) FROM APAF-1
分子名称: APOPTOTIC PROTEASE ACTIVATING FACTOR 1
著者Day, C.L, Dupont, C, Lackmann, M, Vaux, D.L, Hinds, M.G.
登録日1999-08-26
公開日2000-01-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure and mutagenesis of the caspase recruitment domain (CARD) from Apaf-1.
Cell Death Differ., 6, 1999
2SNV
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BU of 2snv by Molmil
THE REFINED STRUCTURE OF SINDBIS VIRUS CORE PROTEIN IN COMPARISON WITH OTHER CHYMOTRYPSIN-LIKE SERINE PROTEINASE STRUCTURES
分子名称: SINDBIS VIRUS COAT PROTEIN
著者Tong, L, Rossmann, M.G.
登録日1992-07-17
公開日1993-10-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Refined structure of Sindbis virus core protein and comparison with other chymotrypsin-like serine proteinase structures.
J.Mol.Biol., 230, 1993
5AF3
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BU of 5af3 by Molmil
X-RAY CRYSTAL STRUCTURE OF RV2018 FROM MYCOBACTERIUM TUBERCULOSIS
分子名称: GLYCEROL, VAPBC49
著者Holton, S.J, Wilmanns, M.
登録日2015-01-18
公開日2016-01-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Crystal Structure and DNA Binding Ability of Myco Tuberculosis Vapbc49 Anti-Toxin Protein Bacterium
To be Published
7PS9
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BU of 7ps9 by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Iberdomide (CC-220)
分子名称: (3S)-3-[4-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)-1-oxo-1,3-dihydro-2H-isoindol-2-yl]piperidine-2,6-dione, Cereblon isoform 4, ZINC ION
著者Heim, C, Hartmann, M.D.
登録日2021-09-22
公開日2022-03-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献High-resolution structures of the bound effectors avadomide (CC-122) and iberdomide (CC-220) highlight advantages and limitations of the MsCI4 soaking system.
Acta Crystallogr D Struct Biol, 78, 2022
5LH0
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BU of 5lh0 by Molmil
Low dose Thaumatin - 0-40 ms.
分子名称: L(+)-TARTARIC ACID, Thaumatin-1
著者Schubert, R, Kapis, S, Heymann, M, Giquel, Y, Bourenkov, G, Schneider, T, Betzel, C, Perbandt, M.
登録日2016-07-08
公開日2016-11-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献A multicrystal diffraction data-collection approach for studying structural dynamics with millisecond temporal resolution.
IUCrJ, 3, 2016
5LN0
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Low dose Thaumatin - 760-800 ms.
分子名称: L(+)-TARTARIC ACID, Thaumatin-1
著者Schubert, R, Kapis, S, Heymann, M, Giquel, Y, Bourenkov, G, Schneider, T, Betzel, C, Perbandt, M.
登録日2016-08-02
公開日2016-11-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献A multicrystal diffraction data-collection approach for studying structural dynamics with millisecond temporal resolution.
IUCrJ, 3, 2016
5LH7
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High dose Thaumatin - 760-800 ms.
分子名称: L(+)-TARTARIC ACID, Thaumatin-1
著者Schubert, R, Kapis, S, Heymann, M, Giquel, Y, Bourenkov, G, Schneider, T, Betzel, C, Perbandt, M.
登録日2016-07-08
公開日2016-11-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献A multicrystal diffraction data-collection approach for studying structural dynamics with millisecond temporal resolution.
IUCrJ, 3, 2016
7NAZ
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TPR-rich domain of EccA3 from M. smegmatis
分子名称: 1,4-DIETHYLENE DIOXIDE, ESX-3 secretion system protein EccA3, GLYCEROL, ...
著者Crosskey, T.D, Wilmanns, M.
登録日2021-01-25
公開日2022-03-02
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of TPR-rich domain of M. smegmatis EccA3
To Be Published
5LH3
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High dose Thaumatin - 0-40 ms.
分子名称: L(+)-TARTARIC ACID, Thaumatin-1
著者Schubert, R, Kapis, S, Heymann, M, Giquel, Y, Bourenkov, G, Schneider, T, Betzel, C, Perbandt, M.
登録日2016-07-08
公開日2016-11-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献A multicrystal diffraction data-collection approach for studying structural dynamics with millisecond temporal resolution.
IUCrJ, 3, 2016
2BUB
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Crystal Structure Of Human Dipeptidyl Peptidase IV (CD26) in Complex with a Reversed Amide Inhibitor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DIPEPTIDYL PEPTIDASE 4, N-({(2S)-1-[(3R)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOYL]PYRROLIDIN-2-YL}METHYL)BENZAMIDE
著者Nordhoff, S, Cerezo-Galvez, S, Feurer, A, Hill, O, Matassa, V.G, Metz, G, Rummey, C, Thiemann, M, Edwards, P.J.
登録日2005-06-09
公開日2006-01-23
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献The reversed binding of beta-phenethylamine inhibitors of DPP-IV: X-ray structures and properties of novel fragment and elaborated inhibitors.
Bioorg. Med. Chem. Lett., 16, 2006
4HUH
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Structure of the bacteriophage T4 tail terminator protein, gp15 (C-terminal truncation mutant 1-261).
分子名称: Tail connector protein Gp15
著者Fokine, A, Zhang, Z, Kanamaru, S, Bowman, V.D, Aksyuk, A, Arisaka, F, Rao, V.B, Rossmann, M.G.
登録日2012-11-02
公開日2013-02-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The molecular architecture of the bacteriophage t4 neck.
J.Mol.Biol., 425, 2013
5J7O
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Faustovirus major capsid protein
分子名称: major capsid protein, unknown
著者Klose, T, Rossmann, M.G.
登録日2016-04-06
公開日2016-05-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Structure of faustovirus, a large dsDNA virus.
Proc.Natl.Acad.Sci.USA, 113, 2016

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