Crystal Structure of DegS protease in complex with an activating peptide

Summary for 1SOZ

Related1SOT 1VCW
DescriptorProtease degS, activating peptide (3 entities in total)
Functional Keywordsstress response, protein quality control, pdz, upr, htra, hydrolase
Biological sourceEscherichia coli
Cellular locationPeriplasm (Potential) P31137
Total number of polymer chains5
Total molecular weight102181.74
Wilken, C.,Kitzing, K.,Kurzbauer, R.,Ehrmann, M.,Clausen, T. (deposition date: 2004-03-16, release date: 2004-06-08, Last modification date: 2011-07-13)
Primary citation
Wilken, C.,Kitzing, K.,Kurzbauer, R.,Ehrmann, M.,Clausen, T.
Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease
Cell(Cambridge,Mass.), 117:483-494, 2004
PubMed: 15137941 (PDB entries with the same primary citation)
DOI: 10.1016/S0092-8674(04)00454-4
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.20734 3.3% 10.2% 17.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-09-23