5AAY
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![BU of 5aay by Molmil](/molmil-images/mine/5aay) | TBK1 recruitment to cytosol-invading Salmonella induces anti- bacterial autophagy | Descriptor: | NF-KAPPA-B ESSENTIAL MODULATOR, ZINC ION | Authors: | Thurston, T.l, Allen, M.D, Ravenhill, B, Karpiyevitch, M, Bloor, S, Kaul, A, Matthews, S, Komander, D, Holden, D, Bycroft, M, Randow, F. | Deposit date: | 2015-07-31 | Release date: | 2016-07-13 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Recruitment of Tbk1 to Cytosol-Invading Salmonella Induces Wipi2-Dependent Antibacterial Autophagy. Embo J., 35, 2016
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3OIK
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![BU of 3oik by Molmil](/molmil-images/mine/3oik) | Human Carbonic anhydrase II mutant A65S, N67Q (CA IX mimic) bound by 2-Ethylestradiol 3,17-O,O-bis-sulfamate | Descriptor: | (9BETA,13ALPHA,14BETA,17ALPHA)-2-ETHYLESTRA-1(10),2,4-TRIENE-3,17-DIYL DISULFAMATE, Carbonic anhydrase 2, GLYCEROL, ... | Authors: | Sippel, K.H, Stander, B.A, Robbins, A.H, Tu, C.K, Agbandje-McKenna, M, Silverman, D.N, Joubert, A.M, McKenna, R. | Deposit date: | 2010-08-19 | Release date: | 2011-07-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds LETT.DRUG DES.DISCOVERY, 8, 2011
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1PO2
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![BU of 1po2 by Molmil](/molmil-images/mine/1po2) | POLIOVIRUS (TYPE 1, MAHONEY) IN COMPLEX WITH R77975, AN INHIBITOR OF VIRAL REPLICATION | Descriptor: | (METHYLPYRIDAZINE PIPERIDINE ETHYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY | Authors: | Hiremath, C.N, Filman, D.J, Grant, R.A, Hogle, J.M. | Deposit date: | 1997-01-08 | Release date: | 1997-12-03 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Ligand-induced conformational changes in poliovirus-antiviral drug complexes. Acta Crystallogr.,Sect.D, 53, 1997
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1PIV
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![BU of 1piv by Molmil](/molmil-images/mine/1piv) | BINDING OF THE ANTIVIRAL DRUG WIN51711 TO THE SABIN STRAIN OF TYPE 3 POLIOVIRUS: STRUCTURAL COMPARISON WITH DRUG BINDING IN RHINOVIRUS 14 | Descriptor: | 5-(7-(4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE, MYRISTIC ACID, POLIOVIRUS TYPE 3 (SUBUNIT VP1), ... | Authors: | Hiremath, C.N, Grant, R.A, Filman, D.J, Hogle, J.M. | Deposit date: | 1995-02-02 | Release date: | 1995-06-03 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Binding of the antiviral drug WIN51711 to the sabin strain of type 3 poliovirus: structural comparison with drug binding in rhinovirus 14. Acta Crystallogr.,Sect.D, 51, 1995
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1QBP
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![BU of 1qbp by Molmil](/molmil-images/mine/1qbp) | |
2H7X
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![BU of 2h7x by Molmil](/molmil-images/mine/2h7x) | Pikromycin Thioesterase adduct with reduced triketide affinity label | Descriptor: | DIMETHYL SULFOXIDE, MAGNESIUM ION, SULFATE ION, ... | Authors: | Giraldes, J.W, Akey, D.L, Kittendorf, J.D, Sherman, D.H, Smith, J.S, Fecik, R.A. | Deposit date: | 2006-06-05 | Release date: | 2006-09-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural and Mechanistic Insights of Polyketide Macrolactonization from Polyketide-based Affinity Labels NAT.CHEM.BIOL., 2, 2006
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3OIM
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![BU of 3oim by Molmil](/molmil-images/mine/3oim) | Human Carbonic anhydrase II bound by 2-Ethylestradiol 3-O-sulfamate | Descriptor: | (14beta,17alpha)-2-ethyl-17-hydroxyestra-1(10),2,4-trien-3-yl sulfamate, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... | Authors: | Sippel, K.H, Stander, B.A, Robbins, A.H, Tu, C.K, Agbandje-McKenna, M, Silverman, D.N, Joubert, A.M, McKenna, R. | Deposit date: | 2010-08-19 | Release date: | 2011-07-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds LETT.DRUG DES.DISCOVERY, 8, 2011
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3OKU
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![BU of 3oku by Molmil](/molmil-images/mine/3oku) | Human Carbonic Anhydrase II in complex with 2-Ethylestrone-3-O-sulfamate | Descriptor: | (9beta)-2-ethyl-17-oxoestra-1(10),2,4-trien-3-yl sulfamate, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... | Authors: | Sippel, K.H, Stander, B.A, Robbins, A.H, Tu, C.K, Agbandje-McKenna, M, Silverman, D.N, Joubert, A.M, McKenna, R. | Deposit date: | 2010-08-25 | Release date: | 2011-07-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds LETT.DRUG DES.DISCOVERY, 8, 2011
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3OIL
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![BU of 3oil by Molmil](/molmil-images/mine/3oil) | Human Carbonic anhydrase II mutant A65S, N67Q (CA IX mimic) bound by 2-Ethylestradiol 3-O-sulfamate | Descriptor: | (14beta,17alpha)-2-ethyl-17-hydroxyestra-1(10),2,4-trien-3-yl sulfamate, Carbonic anhydrase 2, ZINC ION | Authors: | Sippel, K.H, Stander, B.A, Robbins, A.H, Tu, C.K, Agbandje-McKenna, M, Silverman, D.N, Joubert, A.M, McKenna, R. | Deposit date: | 2010-08-19 | Release date: | 2011-07-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds LETT.DRUG DES.DISCOVERY, 8, 2011
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3PE1
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![BU of 3pe1 by Molmil](/molmil-images/mine/3pe1) | Crystal structure of human protein kinase CK2 alpha subunit in complex with the inhibitor CX-4945 | Descriptor: | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, Casein kinase II subunit alpha, SULFATE ION | Authors: | Battistutta, R, Papinutto, E, Lolli, G, Pierre, F, Haddach, M, Ryckman, D.M. | Deposit date: | 2010-10-25 | Release date: | 2011-09-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer. Biochemistry, 50, 2011
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3PE2
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![BU of 3pe2 by Molmil](/molmil-images/mine/3pe2) | Crystal structure of human protein kinase CK2 in complex with the inhibitor CX-5011 | Descriptor: | 5-[(3-ethynylphenyl)amino]pyrimido[4,5-c]quinoline-8-carboxylic acid, Casein kinase II subunit alpha, SULFATE ION | Authors: | Battistutta, R, Papinutto, E, Lolli, G, Pierre, F, Haddach, M, Ryckman, D.M. | Deposit date: | 2010-10-25 | Release date: | 2011-09-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer. Biochemistry, 50, 2011
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3PHX
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![BU of 3phx by Molmil](/molmil-images/mine/3phx) | OTU Domain of Crimean Congo Hemorrhagic Fever Virus in complex with ISG15 | Descriptor: | ACETIC ACID, ETHANAMINE, RNA-directed RNA polymerase L, ... | Authors: | Akutsu, M, Ye, Y, Virdee, S, Komander, D. | Deposit date: | 2010-11-04 | Release date: | 2011-02-02 | Last modified: | 2014-08-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains. Proc.Natl.Acad.Sci.USA, 108, 2011
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2IYL
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![BU of 2iyl by Molmil](/molmil-images/mine/2iyl) | Structure of an FtsY:GDP complex | Descriptor: | CELL DIVISION PROTEIN FTSY, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION | Authors: | Focia, P.J, Freymann, D.M. | Deposit date: | 2006-07-18 | Release date: | 2007-01-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | X-ray structure of the T. aquaticus FtsY:GDP complex suggests functional roles for the C-terminal helix of the SRP GTPases. Proteins, 66, 2007
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1N4H
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![BU of 1n4h by Molmil](/molmil-images/mine/1n4h) | Characterization of ligands for the orphan nuclear receptor RORbeta | Descriptor: | Nuclear Receptor ROR-beta, RETINOIC ACID, Steroid Receptor Coactivator-1 | Authors: | Stehlin-Gaon, C, Willmann, D, Sanglier, S, Van Dorsselaer, A, Renaud, J.-P, Moras, D, Schuele, R. | Deposit date: | 2002-10-31 | Release date: | 2003-09-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | All-trans retinoic acid is a ligand for the orphan nuclear receptor RORbeta Nat.Struct.Biol., 10, 2003
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2JO5
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![BU of 2jo5 by Molmil](/molmil-images/mine/2jo5) | Tetrameric structure of KIA7F peptide | Descriptor: | KIA7F | Authors: | Lopez de la Osa, J, Gonzalez, C, Laurents, D.V, Chakrabartty, A, Bateman, D.A. | Deposit date: | 2007-02-21 | Release date: | 2007-09-18 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Getting specificity from simplicity in putative proteins from the prebiotic earth. Proc.Natl.Acad.Sci.Usa, 104, 2007
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3Q7D
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![BU of 3q7d by Molmil](/molmil-images/mine/3q7d) | Structure of (R)-naproxen bound to mCOX-2. | Descriptor: | (2R)-2-(6-methoxynaphthalen-2-yl)propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Duggan, K.C, Hermanson, D.J, Musee, J, Prusakiewicz, J.J, Scheib, J, Carter, B.D, Banerjee, S, Marnett, L.J. | Deposit date: | 2011-01-04 | Release date: | 2011-11-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | (R)-Profens are substrate-selective inhibitors of endocannabinoid oxygenation by COX-2. Nat.Chem.Biol., 7, 2011
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1NEU
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![BU of 1neu by Molmil](/molmil-images/mine/1neu) | STRUCTURE OF MYELIN MEMBRANE ADHESION MOLECULE P0 | Descriptor: | MYELIN P0 PROTEIN | Authors: | Shapiro, L, Doyle, J.P, Hensley, P, Colman, D.R, Hendrickson, W.A. | Deposit date: | 1996-09-24 | Release date: | 1997-05-15 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the extracellular domain from P0, the major structural protein of peripheral nerve myelin. Neuron, 17, 1996
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2JY5
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![BU of 2jy5 by Molmil](/molmil-images/mine/2jy5) | NMR structure of Ubiquilin 1 UBA domain | Descriptor: | Ubiquilin-1 | Authors: | Zhang, D, Raasi, S, Fushman, D. | Deposit date: | 2007-12-06 | Release date: | 2008-03-18 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Affinity makes the difference: nonselective interaction of the UBA domain of Ubiquilin-1 with monomeric ubiquitin and polyubiquitin chains J.Mol.Biol., 377, 2008
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2IDV
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![BU of 2idv by Molmil](/molmil-images/mine/2idv) | Crystal structure of wheat C113S mutant EIF4E bound TO 7-methyl-GDP | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Eukaryotic translation initiation factor 4E-1 | Authors: | Monzingo, A.F, Dutt-Chaudhuri, A, Sadow, J, Dhaliwal, S, Hoffman, D.W, Robertus, J.D, Browning, K.S. | Deposit date: | 2006-09-15 | Release date: | 2007-06-12 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The structure of eukaryotic translation initiation factor-4E from wheat reveals a novel disulfide bond. Plant Physiol., 143, 2007
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7MVZ
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![BU of 7mvz by Molmil](/molmil-images/mine/7mvz) | Single particle cryo-EM structure of the Chaetomium thermophilum Nup188-Nic96-Nup145N complex (Nup188 residues 1-1858; Nic96 residues 240-301; Nup145N residues 640-732) | Descriptor: | Nucleoporin NIC96, Nucleoporin NUP145N, Nucleoporin NUP188 | Authors: | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | Deposit date: | 2021-05-15 | Release date: | 2022-06-15 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.81 Å) | Cite: | Architecture of the linker-scaffold in the nuclear pore. Science, 376, 2022
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7MVT
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![BU of 7mvt by Molmil](/molmil-images/mine/7mvt) | Crystal structure of the Chaetomium thermophilum Nup192-Nic96 complex (Nup192 residues 185-1756; Nic96 residues 187-301) | Descriptor: | Nucleoporin NIC96, Nucleoporin NUP192 | Authors: | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | Deposit date: | 2021-05-15 | Release date: | 2022-06-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Architecture of the linker-scaffold in the nuclear pore. Science, 376, 2022
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7MVU
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![BU of 7mvu by Molmil](/molmil-images/mine/7mvu) | Single particle cryo-EM structure of the Chaetomium thermophilum Nup192-Nic96 complex (Nup192 residues 1-1756; Nic96 residues 240-301) | Descriptor: | Nucleoporin NIC96, Nucleoporin NUP192 | Authors: | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | Deposit date: | 2021-05-15 | Release date: | 2022-06-15 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.77 Å) | Cite: | Architecture of the linker-scaffold in the nuclear pore. Science, 376, 2022
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3RBH
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![BU of 3rbh by Molmil](/molmil-images/mine/3rbh) | Structure of alginate export protein AlgE from Pseudomonas aeruginosa | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, 1,2-ETHANEDIOL, Alginate production protein AlgE, ... | Authors: | Whitney, J.C, Hay, I.D, Li, C, Eckford, P.D, Robinson, H, Amaya, M.F, Wood, L.F, Ohman, D.E, Bear, C.E, Rehm, B.H, Howell, P.L. | Deposit date: | 2011-03-29 | Release date: | 2011-07-27 | Last modified: | 2011-08-24 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Structural basis for alginate secretion across the bacterial outer membrane. Proc.Natl.Acad.Sci.USA, 108, 2011
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7MVY
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![BU of 7mvy by Molmil](/molmil-images/mine/7mvy) | Single particle cryo-EM structure of the Chaetomium thermophilum Nup188-Nic96 complex (Nup188 residues 1-1858; Nic96 residues 240-301) | Descriptor: | Nucleoporin NIC96, Nucleoporin NUP188 | Authors: | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | Deposit date: | 2021-05-15 | Release date: | 2022-06-15 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.39 Å) | Cite: | Architecture of the linker-scaffold in the nuclear pore. Science, 376, 2022
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2JWZ
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![BU of 2jwz by Molmil](/molmil-images/mine/2jwz) | Mutations in the hydrophobic core of ubiquitin differentially affect its recognition by receptor proteins | Descriptor: | Ubiquitin | Authors: | Haririnia, A, Verma, R, Purohit, N, Twarog, M, Deshaies, R, Bolon, D, Fushman, D. | Deposit date: | 2007-10-31 | Release date: | 2008-01-08 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Mutations in the hydrophobic core of ubiquitin differentially affect its recognition by receptor proteins. J.Mol.Biol., 375, 2008
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