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PDB: 60 件
4UZG
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BU of 4uzg by Molmil
Crystal structure of group B streptococcus pilus 2b backbone protein SAK_1440
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, SURFACE PROTEIN SPB1
著者Malito, E, Cozzi, R, Bottomley, M.J.
登録日2014-09-05
公開日2015-05-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.06 Å)
主引用文献Structure and assembly of group B streptococcus pilus 2b backbone protein.
PLoS ONE, 10, 2015
5FLY
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BU of 5fly by Molmil
The FhuD protein from S.pseudintermedius
分子名称: 2,5,8,11,14,17,20,23-OCTAOXAPENTACOSAN-25-OL, CADMIUM ION, CHLORIDE ION, ...
著者Malito, E.
登録日2015-10-29
公開日2015-12-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.598 Å)
主引用文献Crystal Structure of Fhud at 1.6 Angstrom Resolution: A Ferrichrome-Binding Protein from the Animal and Human Pathogen Staphylococcus Pseudintermedius
Acta Crystallogr.,Sect.F, 72, 2016
3O0P
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BU of 3o0p by Molmil
Pilus-related Sortase C of Group B Streptococcus
分子名称: Sortase family protein
著者Malito, E, Spraggon, G.
登録日2010-07-19
公開日2011-03-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structure analysis and site-directed mutagenesis of defined key residues and motives for pilus-related sortase C1 in group B Streptococcus.
Faseb J., 25, 2011
6VJB
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BU of 6vjb by Molmil
Crystal structure of a catalytically inactive CXC Chemokine-degrading protease SpyCEP from Streptococcus pyogenes
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Putative cell envelope proteinase
著者Malito, E, Rouse, S.
登録日2020-01-15
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Structure, dynamics and immunogenicity of a catalytically inactive CXC chemokine-degrading protease SpyCEP from Streptococcus pyogenes.
Comput Struct Biotechnol J, 18, 2020
3E4A
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BU of 3e4a by Molmil
Human IDE-inhibitor complex at 2.6 angstrom resolution
分子名称: 1,4-DIETHYLENE DIOXIDE, ACETIC ACID, HYDROXAMATE PEPTIDE II1, ...
著者Malito, E, Leissring, M.A, Choi, S, Cuny, G.D, Tang, W.J.
登録日2008-08-11
公開日2009-05-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin.
Plos One, 5, 2010
6CUJ
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BU of 6cuj by Molmil
Crystal structure of the C-terminal domain of neisserial heparin binding antigen (NHBA)
分子名称: Gna2132
著者Malito, E, Spraggon, G.
登録日2018-03-26
公開日2018-09-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.805 Å)
主引用文献Structures of NHBA elucidate a broadly conserved epitope identified by a vaccine induced antibody.
PLoS ONE, 13, 2018
2YPV
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BU of 2ypv by Molmil
Crystal structure of the Meningococcal vaccine antigen factor H binding protein in complex with a bactericidal antibody
分子名称: 1,2-ETHANEDIOL, FAB 12C1, LIPOPROTEIN
著者Malito, E, Veggi, D, Bottomley, M.J.
登録日2012-11-01
公開日2013-02-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Defining a Protective Epitope on Factor H Binding Protein, a Key Meningococcal Virulence Factor and Vaccine Antigen.
Proc.Natl.Acad.Sci.USA, 110, 2013
5T5F
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BU of 5t5f by Molmil
Neisseria meningitidis factor H binding protein in complex with monoclonal antibody JAR5
分子名称: Factor H binding protein variant B24, Monoclonal antibody Jar5 heavy chain, Monoclonal antibody Jar5 light chain
著者Malito, E.
登録日2016-08-30
公開日2016-11-09
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Neisseria meningitidis factor H-binding protein bound to monoclonal antibody JAR5: implications for antibody synergy.
Biochem. J., 473, 2016
2Y7S
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BU of 2y7s by Molmil
Structure of a designed meningococcal antigen (factor H binding protein, mutant G1) inducing broad protective immunity
分子名称: FACTOR H BINDING PROTEIN
著者Malito, E, Spraggon, G, Bottomley, M.J.
登録日2011-02-01
公開日2011-07-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Rational Design of a Meningococcal Antigen Inducing Broad Protective Immunity.
Sci.Transl.Med, 3, 2011
5VOD
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BU of 5vod by Molmil
Crystal structure of HCMV Pentamer in complex with neutralizing antibody 9I6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ...
著者Malito, E, Chandramouli, S.
登録日2017-05-02
公開日2017-07-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (5.9 Å)
主引用文献Structural basis for potent antibody-mediated neutralization of human cytomegalovirus.
Sci Immunol, 2, 2017
5VOB
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BU of 5vob by Molmil
Crystal structure of HCMV Pentamer in complex with neutralizing antibody 8I21
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ...
著者Malito, E, Chandramouli, S.
登録日2017-05-02
公開日2017-07-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.02 Å)
主引用文献Structural basis for potent antibody-mediated neutralization of human cytomegalovirus.
Sci Immunol, 2, 2017
5VOC
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BU of 5voc by Molmil
Crystal structure of HCMV Pentamer in complex with neutralizing antibody 8I21 - Low resolution dataset for initial phasing by SAD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ...
著者Malito, E, Chandramouli, S.
登録日2017-05-02
公開日2017-07-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.99 Å)
主引用文献Structural basis for potent antibody-mediated neutralization of human cytomegalovirus.
Sci Immunol, 2, 2017
4CJD
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BU of 4cjd by Molmil
Crystal structure of Neisseria meningitidis trimeric autotransporter and vaccine antigen NadA
分子名称: IODIDE ION, NADA
著者Malito, E, Biancucci, M, Spraggon, G, Bottomley, M.J.
登録日2013-12-19
公開日2014-11-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.056 Å)
主引用文献Structure of the Meningococcal Vaccine Antigen Nada and Epitope Mapping of a Bactericidal Antibody.
Proc.Natl.Acad.Sci.USA, 111, 2014
2CKO
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BU of 2cko by Molmil
Crystal structure of Human Choline Kinase alpha 2
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHOLINE KINASE ALPHA
著者Malito, E, Lavie, A.
登録日2006-04-20
公開日2006-10-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Elucidation of Human Choline Kinase Crystal Structures in Complex with the Products Adp or Phosphocholine.
J.Mol.Biol., 364, 2006
2CKP
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BU of 2ckp by Molmil
Crystal structure of Human Choline Kinase alpha-2 in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, CHOLINE KINASE ALPHA
著者Malito, E, Lavie, A.
登録日2006-04-20
公開日2006-10-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Elucidation of Human Choline Kinase Crystal Structures in Complex with the Products Adp or Phosphocholine.
J.Mol.Biol., 364, 2006
2CKQ
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BU of 2ckq by Molmil
Crystal structure of Human Choline Kinase alpha 2 in complex with Phosphocholine
分子名称: CHOLINE KINASE ALPHA, PHOSPHOCHOLINE
著者Malito, E, Lavie, A.
登録日2006-04-20
公開日2006-10-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Elucidation of Human Choline Kinase Crystal Structures in Complex with the Products Adp or Phosphocholine.
J.Mol.Biol., 364, 2006
5NYX
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BU of 5nyx by Molmil
human Fab fragment 5H2 against NHBA from Neisseria meningitidis
分子名称: GLYCEROL, HEAVY CHAIN, LIGHT CHAIN, ...
著者Malito, E, Maritan, M.
登録日2017-05-12
公開日2018-05-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structures of NHBA elucidate a broadly conserved epitope identified by a vaccine induced antibody.
PLoS ONE, 13, 2018
5O1R
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BU of 5o1r by Molmil
human Fab 5H2 bound to NHBA-C3 from Neisseria meningitidis serogroup B
分子名称: 1,2-ETHANEDIOL, GNA2132, IGH@ protein, ...
著者Malito, E, Maritan, M.
登録日2017-05-19
公開日2018-05-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Structures of NHBA elucidate a broadly conserved epitope identified by a vaccine induced antibody.
PLoS ONE, 13, 2018
4AE1
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BU of 4ae1 by Molmil
Crystal structure of diphtheria toxin mutant CRM197 in complex with nicotinamide
分子名称: DIPHTHERIA TOXIN, NICOTINAMIDE
著者Malito, E, Spraggon, G.
登録日2012-01-04
公開日2012-03-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.078 Å)
主引用文献Structural Basis for Lack of Toxicity of the Diphtheria Toxin Mutant Crm197.
Proc.Natl.Acad.Sci.USA, 109, 2012
4AE0
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BU of 4ae0 by Molmil
Crystal structure of diphtheria toxin mutant CRM197
分子名称: DIPHTHERIA TOXIN
著者Malito, E, Spraggon, G.
登録日2012-01-04
公開日2012-03-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.996 Å)
主引用文献Structural Basis for Lack of Toxicity of the Diphtheria Toxin Mutant Crm197.
Proc.Natl.Acad.Sci.USA, 109, 2012
4BIG
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BU of 4big by Molmil
Crystal structure of the conserved staphylococcal antigen 1B, Csa1B
分子名称: UNCHARACTERIZED LIPOPROTEIN SAOUHSC_00053
著者Malito, E, Bottomley, M.J, Schluepen, C, Liberatori, S.
登録日2013-04-10
公開日2013-08-07
最終更新日2013-10-30
実験手法X-RAY DIFFRACTION (2.274 Å)
主引用文献Mining the Bacterial Unknown Proteome: Identification and Characterization of a Novel Family of Highly Conserved Protective Antigens in Staphylococcus Aureus
Biochem.J., 455, 2013
4BIH
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BU of 4bih by Molmil
Crystal structure of the conserved staphylococcal antigen 1A, Csa1A
分子名称: CALCIUM ION, UNCHARACTERIZED LIPOPROTEIN SAOUHSC_00053
著者Malito, E, Bottomley, M.J, Spraggon, G, Schluepen, C, Liberatori, S.
登録日2013-04-10
公開日2013-08-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.459 Å)
主引用文献Mining the Bacterial Unknown Proteome: Identification and Characterization of a Novel Family of Highly Conserved Protective Antigens in Staphylococcus Aureus
Biochem.J., 455, 2013
3CWW
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BU of 3cww by Molmil
Crystal Structure of IDE-bradykinin complex
分子名称: 1,4-DIETHYLENE DIOXIDE, ACETATE ION, Insulin-degrading enzyme, ...
著者Malito, E, Tang, W.J.
登録日2008-04-23
公開日2008-11-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Molecular Bases for the Recognition of Short Peptide Substrates and Cysteine-Directed Modifications of Human Insulin-Degrading Enzyme
Biochemistry, 47, 2008
4DMW
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BU of 4dmw by Molmil
Crystal structure of the GT domain of Clostridium difficile toxin A (TcdA) in complex with UDP and Manganese
分子名称: MANGANESE (II) ION, Toxin A, URIDINE-5'-DIPHOSPHATE
著者Malito, E, D'Urzo, N, Bottomley, M.J, Biancucci, M, Scarselli, M, Maione, D, Martinelli, M.
登録日2012-02-08
公開日2012-07-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structure of Clostridium difficile toxin A glucosyltransferase domain bound to Mn2+ and UDP provides insights into glucosyltransferase activity and product release.
Febs J., 279, 2012
4DMV
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BU of 4dmv by Molmil
Crystal structure of the GT domain of Clostridium difficile Toxin A
分子名称: Toxin A
著者Malito, E, D'Urzo, N, Bottomley, M.J, Biancucci, M, Maione, D, Scarselli, M, Martinelli, M.
登録日2012-02-08
公開日2012-07-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The structure of Clostridium difficile toxin A glucosyltransferase domain bound to Mn2+ and UDP provides insights into glucosyltransferase activity and product release.
Febs J., 279, 2012

 

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