2J9J
Atomic-resolution Crystal Structure of Chemically-Synthesized HIV-1 Protease Complexed with Inhibitor JG-365
Summary for 2J9J
Entry DOI | 10.2210/pdb2j9j/pdb |
Related PRD ID | PRD_000228 |
Descriptor | PROTEASE, INHIBITOR MOLECULE JG365, SULFATE ION, ... (7 entities in total) |
Functional Keywords | hydrolase-hydrolase inhibitor complex, protease, hydrolase, high resolution, rna-directed dna polymerase, aspartyl protease, human immunodeficiency virus 1, hydrolase- hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | HUMAN IMMUNODEFICIENCY VIRUS 1 More |
Total number of polymer chains | 3 |
Total formula weight | 22855.72 |
Authors | Malito, E.,Shen, Y.,Johnson, E.C.B.,Tang, W.J. (deposition date: 2006-11-11, release date: 2007-08-28, Last modification date: 2023-12-13) |
Primary citation | Johnson, E.C.B.,Malito, E.,Shen, Y.,Pentelute, B.,Rich, D.,Florian, J.,Tang, W.J.,Kent, S.B.H. Insights from Atomic-Resolution X-Ray Structures of Chemically Synthesized HIV-1 Protease in Complex with Inhibitors. J.Mol.Biol., 373:573-, 2007 Cited by PubMed: 17869270DOI: 10.1016/J.JMB.2007.07.054 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.04 Å) |
Structure validation
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