Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1105 |
| Chain | Residue |
| A | PRO1 |
| A | ASN37 |
| A | ARG57 |
| A | HIS69 |
| A | HOH2119 |
| B | HOH2102 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1106 |
| Chain | Residue |
| A | HOH2121 |
| A | HOH2122 |
| B | ARG14 |
| B | GLY17 |
| B | PRO63 |
| A | ARG14 |
| A | HOH2033 |
| A | HOH2120 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 1107 |
| Chain | Residue |
| A | PHE99 |
| A | HOH2088 |
| A | HOH2123 |
| B | NLE46 |
| B | PHE53 |
| B | LYS55 |
| B | HIS69 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 1108 |
| Chain | Residue |
| A | THR12 |
| A | SLZ41 |
| A | TRP42 |
| A | ABA67 |
| A | HOH2124 |
| A | HOH2125 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1105 |
| Chain | Residue |
| A | GLY68 |
| A | HIS69 |
| A | LYS70 |
| A | HOH2088 |
| B | PRO1 |
| B | LYS55 |
| B | HOH2109 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT B 1106 |
| Chain | Residue |
| A | LYS55 |
| A | LYS70 |
| B | ARG14 |
| B | LYS70 |
| B | HOH2110 |
| B | HOH2112 |
| site_id | AC7 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR CHAIN C OF INHIBITOR MOLECULE JG365 |
| Chain | Residue |
| A | ARG8 |
| A | ASP25 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | ASP30 |
| A | LYS45 |
| A | ILE47 |
| A | GLY48 |
| A | GLY49 |
| A | ILE50 |
| A | ILE84 |
| A | HOH2046 |
| A | HOH2064 |
| B | ASP25 |
| B | GLY27 |
| B | ALA28 |
| B | ASP29 |
| B | GLY48 |
| B | GLY49 |
| B | VAL82 |
| B | ILE84 |
| B | HOH2066 |
| B | HOH2106 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
| Chain | Residue | Details |
| A | ALA22-ILE33 | |
| B | ALA22-ILE33 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| B | ASP25 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| B | PHE99 | |
