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PDB: 320 results

4QKY
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Crystal Structure Analysis of the Membrane Transporter FhaC
Descriptor: Filamentous hemagglutinin transporter protein FhaC, PHOSPHATE ION
Authors:Maier, T, Clantin, B, Gruss, F, Dewitte, F, Delattre, A.S, Jacob-Dubuisson, F, Hiller, S, Villeret, V.
Deposit date:2014-06-10
Release date:2014-10-22
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Conserved Omp85 lid-lock structure and substrate recognition in FhaC
Nat Commun, 6, 2015
4QL0
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Crystal Structure Analysis of the Membrane Transporter FhaC (double mutant V169T, I176N)
Descriptor: DI(HYDROXYETHYL)ETHER, Filamentous hemagglutinin transporter protein FhaC, HEXAETHYLENE GLYCOL, ...
Authors:Maier, T, Clantin, B, Gruss, F, Dewitte, F, Delattre, A.S, Jacob-Dubuisson, F, Hiller, S, Villeret, V.
Deposit date:2014-06-10
Release date:2015-06-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Conserved Omp85 lid-lock structure and substrate recognition in FhaC
Nat Commun, 6, 2015
2VZ9
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Crystal Structure of Mammalian Fatty Acid Synthase in complex with NADP
Descriptor: FATTY ACID SYNTHASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Maier, T, Leibundgut, M, Ban, N.
Deposit date:2008-07-31
Release date:2008-09-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The Crystal Structure of a Mammalian Fatty Acid Synthase.
Science, 321, 2008
2VZ8
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Crystal Structure of Mammalian Fatty Acid Synthase
Descriptor: FATTY ACID SYNTHASE
Authors:Maier, T, Leibundgut, M, Ban, N.
Deposit date:2008-07-31
Release date:2008-09-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.219 Å)
Cite:The Crystal Structure of a Mammalian Fatty Acid Synthase.
Science, 321, 2008
1O7A
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BU of 1o7a by Molmil
Human beta-Hexosaminidase B
Descriptor: 1,2-ETHANEDIOL, 2-(acetylamido)-2-deoxy-D-glucono-1,5-lactone, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Maier, T, Strater, N, Schuette, C, Klingenstein, R, Sandhoff, K, Saenger, W.
Deposit date:2002-10-29
Release date:2003-10-23
Last modified:2020-11-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The X-Ray Crystal Structure of Human Beta-Hexosaminidase B Provides New Insights Into Sandhoff Disease
J.Mol.Biol., 328, 2003
2R1Q
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BU of 2r1q by Molmil
Crystal Structure of Iodinated Human Saposin D in Space Group C2221
Descriptor: Proactivator polypeptide
Authors:Maier, T, Rossman, M, Saenger, W.
Deposit date:2007-08-23
Release date:2008-04-29
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
2RB3
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BU of 2rb3 by Molmil
Crystal Structure of Human Saposin D
Descriptor: GLYCEROL, Proactivator polypeptide, SULFATE ION
Authors:Maier, T, Rossman, M, Saenger, W.
Deposit date:2007-09-18
Release date:2008-04-29
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
2BJ6
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BU of 2bj6 by Molmil
Crystal Structure of a decameric HNA-RNA hybrid
Descriptor: 5'-R(*GP*GP*CP*AP*UP*UP*AP*CP*GP*GP)-3', SULFATE ION, SYNTHETIC HNA
Authors:Maier, T, Przylas, I, Straeter, N, Herdewijn, P, Saenger, W.
Deposit date:2005-01-30
Release date:2005-03-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Reinforced Hna Backbone Hydration in the Crystal Structure of a Decameric Hna/RNA Hybrid
J.Am.Chem.Soc., 127, 2005
2CF2
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BU of 2cf2 by Molmil
Architecture of mammalian fatty acid synthase
Descriptor: FATTY ACID SYNTHASE, DH DOMAIN, ER DOMAIN, ...
Authors:Maier, T, Jenni, S, Ban, N.
Deposit date:2006-02-14
Release date:2006-03-07
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Architecture of Mammalian Fatty Acid Synthase at 4.5 A Resolution.
Science, 311, 2006
4RQV
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Crystal structure of PDK1 in complex with ATP and the PIF-pocket ligand RS2
Descriptor: 3-phosphoinositide-dependent protein kinase 1, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ...
Authors:Rettenmaier, T.J, Wells, J.A.
Deposit date:2014-11-05
Release date:2014-12-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.502 Å)
Cite:A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1.
Proc.Natl.Acad.Sci.USA, 111, 2014
4RQK
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Crystal structure of PDK1 in complex with ATP and the PIF-pocket ligand RS1
Descriptor: 3-phosphoinositide-dependent protein kinase 1, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Rettenmaier, T.J, Wells, J.A.
Deposit date:2014-11-03
Release date:2014-12-17
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1.
Proc.Natl.Acad.Sci.USA, 111, 2014
4RRV
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BU of 4rrv by Molmil
Crystal structure of PDK1 in complex with ATP and PIFtide
Descriptor: 3-phosphoinositide-dependent protein kinase 1, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ...
Authors:Rettenmaier, T.J, Wells, J.A.
Deposit date:2014-11-06
Release date:2014-12-17
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.412 Å)
Cite:A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1.
Proc.Natl.Acad.Sci.USA, 111, 2014
4XX9
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BU of 4xx9 by Molmil
Crystal structure of PDK1 in complex with ATP and the PIF-pocket ligand RF4
Descriptor: (2-{[2-(2,6-dimethylphenoxy)ethyl]sulfanyl}-1H-benzimidazol-1-yl)acetic acid, 3-phosphoinositide-dependent protein kinase 1, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Rettenmaier, T.J, Wells, J.A.
Deposit date:2015-01-29
Release date:2015-10-21
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Small-Molecule Allosteric Modulators of the Protein Kinase PDK1 from Structure-Based Docking.
J.Med.Chem., 58, 2015
5OOW
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BU of 5oow by Molmil
Crystal structure of lobe II from the nucleotide binding domain of DnaK in complex with AMPPCP
Descriptor: Chaperone protein DnaK, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
Authors:Jakob, R.P, Bauer, D, Meinhold, S, Stigler, J, Merkel, U, Maier, T, Rief, M, Zoldak, G.
Deposit date:2017-08-09
Release date:2018-04-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A folding nucleus and minimal ATP binding domain of Hsp70 identified by single-molecule force spectroscopy.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6ZWO
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BU of 6zwo by Molmil
cryo-EM structure of human mTOR complex 2, focused on one half
Descriptor: ACETYL GROUP, INOSITOL HEXAKISPHOSPHATE, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Scaiola, A, Mangia, F, Imseng, S, Boehringer, D, Ban, N, Maier, T.
Deposit date:2020-07-28
Release date:2020-11-18
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The 3.2- angstrom resolution structure of human mTORC2.
Sci Adv, 6, 2020
5JCQ
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BU of 5jcq by Molmil
Crystal structure of the FimH lectin domain from E.coli K12 in complex with methyl alpha-D-mannopyrannoside in spacegroup P21
Descriptor: Protein FimH, SULFATE ION, methyl alpha-D-mannopyranoside
Authors:Jakob, R.P, Rabbani, S, Ernst, B, Maier, T.
Deposit date:2016-04-15
Release date:2017-05-10
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.602 Å)
Cite:Crystal structure of the FimH lectin domain from E.coli K12 in complex with methyl alpha-D-mannopyrannoside in spacegroup P21
To Be Published
8CPQ
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BU of 8cpq by Molmil
Crystal structure of human protein disulfide isomerase PDIA6 domain b
Descriptor: Protein disulfide-isomerase A6
Authors:Jakob, R.P, Leder, A.L, Hiller, S, Maier, T.
Deposit date:2023-03-03
Release date:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of human protein disulfide isomerase PDIA6 domain b
To Be Published
8CQR
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BU of 8cqr by Molmil
Cryo-EM structure of the NINJ1 filament
Descriptor: Ninjurin-1
Authors:Degen, M.D, Hiller, S.H, Maier, T.M.
Deposit date:2023-03-07
Release date:2023-05-17
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of NINJ1-mediated plasma membrane rupture in cell death.
Nature, 618, 2023
6YL3
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BU of 6yl3 by Molmil
High resolution cryo-EM structure of urease from the pathogen Yersinia enterocolitica
Descriptor: NICKEL (II) ION, Urease subunit alpha, Urease subunit beta, ...
Authors:Righetto, R.D, Anton, L, Adaixo, R, Jakob, R, Zivanov, J, Mahi, M.A, Ringler, P, Schwede, T, Maier, T, Stahlberg, H.
Deposit date:2020-04-06
Release date:2020-05-06
Last modified:2020-10-21
Method:ELECTRON MICROSCOPY (1.98 Å)
Cite:High-resolution cryo-EM structure of urease from the pathogen Yersinia enterocolitica.
Nat Commun, 11, 2020
3J9G
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BU of 3j9g by Molmil
Atomic model of the VipA/VipB, the type six secretion system contractile sheath of Vibrio cholerae from cryo-EM
Descriptor: VipA, VipB
Authors:Kudryashev, M, Wang, R.Y.-R, Brackmann, M, Scherer, S, Maier, T, Baker, D, DiMaio, F, Stahlberg, H, Egelman, E.H, Basler, M.
Deposit date:2015-01-16
Release date:2015-03-11
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the Type VI Secretion System Contractile Sheath.
Cell(Cambridge,Mass.), 160, 2015
7R1V
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BU of 7r1v by Molmil
Crystal structure of E.coli BamA beta-barrel in complex with dynobactin A
Descriptor: Dynobactin A, Outer membrane protein assembly factor BamA
Authors:Jakob, R.P, Hiller, S, Maier, T.
Deposit date:2022-02-03
Release date:2022-09-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Computational identification of a systemic antibiotic for gram-negative bacteria.
Nat Microbiol, 7, 2022
8R5M
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BU of 8r5m by Molmil
E-selectin complexed with glycomimetic ligand DS0567
Descriptor: (2~{S})-3-cyclohexyl-2-[(2~{R},3~{R},4~{S},5~{S},6~{R})-2-[(1~{R},2~{R},3~{S})-3-ethyl-2-[(2~{S},3~{S},4~{R},5~{S},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-cyclohexyl]oxy-6-(hydroxymethyl)-5-oxidanyl-3-(phenylcarbonyloxy)oxan-4-yl]oxy-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Jakob, R.P, Ernst, B, Maier, T.
Deposit date:2023-11-17
Release date:2024-10-23
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Analogues of the pan-selectin antagonist rivipansel (GMI-1070).
Eur.J.Med.Chem., 272, 2024
8R5L
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BU of 8r5l by Molmil
E-selectin complexed with glycomimetic ligand BW850
Descriptor: (2~{S})-3-cyclohexyl-2-[(2~{R},3~{R},4~{S},5~{S},6~{R})-2-[(1~{R},2~{R},3~{S},5~{R})-3-ethyl-2-[(2~{S},3~{S},4~{R},5~{S},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5-[3-[1-[3-oxidanylidene-3-[(3,6,8-trisulfonaphthalen-1-yl)amino]propyl]-1,2,3-triazol-4-yl]propylcarbamoyl]cyclohexyl]oxy-6-(hydroxymethyl)-5-oxidanyl-3-(phenylcarbonyloxy)oxan-4-yl]oxy-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Jakob, R.P, Ernst, B, Maier, T.
Deposit date:2023-11-17
Release date:2024-10-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Analogues of the pan-selectin antagonist rivipansel (GMI-1070).
Eur.J.Med.Chem., 272, 2024
6SWR
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BU of 6swr by Molmil
Crystal structure of the lysosomal potassium channel MtTMEM175 T38A mutant soaked with zinc
Descriptor: DODECYL-BETA-D-MALTOSIDE, Nanobody, Maltose/maltodextrin-binding periplasmic protein,Maltodextrin-binding protein,Maltose/maltodextrin-binding periplasmic protein, ...
Authors:Brunner, J.D, Jakob, R.P, Schulze, T, Neldner, Y, Moroni, A, Thiel, G, Maier, T, Schenck, S.
Deposit date:2019-09-23
Release date:2020-04-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for ion selectivity in TMEM175 K + channels.
Elife, 9, 2020
2QYP
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Orthorhombic Crystal Structure of Human Saposin C Dimer in Open Conformation
Descriptor: Proactivator polypeptide
Authors:Rossmann, M, Saenger, W, Maier, T.
Deposit date:2007-08-15
Release date:2008-04-29
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008

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