6SWR

Crystal structure of the lysosomal potassium channel MtTMEM175 T38A mutant soaked with zinc

Summary for 6SWR

Entry DOI	10.2210/pdb6swr/pdb
Related	6HD8 6HD9 6HDA 6HDB 6HDC
Related PRD ID	PRD_900001
Descriptor	Nanobody, Maltose/maltodextrin-binding periplasmic protein,Maltodextrin-binding protein,Maltose/maltodextrin-binding periplasmic protein, Uncharacterized protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (6 entities in total)
Functional Keywords	lysosome, tmem175, potassium channel, parkinson disease, transport protein
Biological source	Lama glama (llama) More
Total number of polymer chains	4
Total formula weight	167180.82
Authors	Brunner, J.D.,Jakob, R.P.,Schulze, T.,Neldner, Y.,Moroni, A.,Thiel, G.,Maier, T.,Schenck, S. (deposition date: 2019-09-23, release date: 2020-04-15, Last modification date: 2024-01-24)
Primary citation	Brunner, J.D.,Jakob, R.P.,Schulze, T.,Neldner, Y.,Moroni, A.,Thiel, G.,Maier, T.,Schenck, S. Structural basis for ion selectivity in TMEM175 K + channels. Elife, 9:-, 2020 Cited by PubMed: 32267231 DOI: 10.7554/eLife.53683 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation