6SWR

Crystal structure of the lysosomal potassium channel MtTMEM175 T38A mutant soaked with zinc

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, D)	Nanobody, Maltose/maltodextrin-binding periplasmic protein,Maltodextrin-binding protein,Maltose/maltodextrin-binding periplasmic protein	polymer	486	53267.0	2	UniProt (P0AEX9) Pfam (PF01547)	Lama glama (llama)	MMBP,Maltodextrin-binding protein,Maltose-binding protein,MBP
2	B, D (B, E)	Uncharacterized protein	polymer	255	29450.9	2	UniProt (E4TN31) Pfam (PF06736)	Marivirga tractuosa (strain ATCC 23168 / DSM 4126 / NBRC 15989 / NCIMB 1408 / VKM B-1430 / H-43) (Microscilla tractuosa)
3	E, F (C, F)	alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose	branched		342.3	2	In PDB BIRD (PRD_900001) GlyTouCan (G07411ON)		alpha-maltose
4	G, I (B, E)	DODECYL-BETA-D-MALTOSIDE	non-polymer		510.6	2	Chemie (LMT)
5	H (B)	POTASSIUM ION	non-polymer		39.1	1	Chemie (K)
6	J, K, L, M (A, B, D, E)	water	water		18.0	31	Chemie (HOH)

Sequence modifications

A, D: 1 - 122 (PDB: 6SWR)
A, D: null - 486 (UniProt: P0AEX9)

PDB	External Database	Details
Pro 484	Arg 393	conflict
Gly 485	Ile 394	conflict
Ala 486	Thr 395	conflict

B, E: 2 - 247 (UniProt: E4TN31)

PDB	External Database	Details
Met 0	-	initiating methionine
Ser 1	-	expression tag
Ala 38	Thr 38	conflict
Ala 248	-	expression tag
Leu 249	-	expression tag
Glu 250	-	expression tag
Val 251	-	expression tag
Leu 252	-	expression tag
Phe 253	-	expression tag
Gln 254	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	165435.9
Branched	Number of molecules	2
	Total formula weight	684.6
Non-Polymers*	Number of molecules	3
	Total formula weight	1060.3
All*	Total formula weight	167180.8

*Water molecules are not included.