2R1Q
Crystal Structure of Iodinated Human Saposin D in Space Group C2221
Summary for 2R1Q
| Entry DOI | 10.2210/pdb2r1q/pdb |
| Related | 2QYP 2R0R 2RB3 2Z9A |
| Descriptor | Proactivator polypeptide (2 entities in total) |
| Functional Keywords | lipid binding protein, saposin, activator protein, sap, alternative splicing, disease mutation, gaucher disease, glycoprotein, gm2-gangliosidosis, lipid metabolism, lysosome, metachromatic leukodystrophy, sphingolipid metabolism |
| Biological source | Homo sapiens (human) |
| Cellular location | Lysosome . Prosaposin: Secreted : P07602 |
| Total number of polymer chains | 1 |
| Total formula weight | 9780.05 |
| Authors | Maier, T.,Rossman, M.,Saenger, W. (deposition date: 2007-08-23, release date: 2008-04-29, Last modification date: 2017-10-25) |
| Primary citation | Rossmann, M.,Schultz-Heienbrok, R.,Behlke, J.,Remmel, N.,Alings, C.,Sandhoff, K.,Saenger, W.,Maier, T. Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions. Structure, 16:809-817, 2008 Cited by PubMed: 18462685DOI: 10.1016/j.str.2008.02.016 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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