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PDB: 320 件

4QKY
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Crystal Structure Analysis of the Membrane Transporter FhaC
分子名称: Filamentous hemagglutinin transporter protein FhaC, PHOSPHATE ION
著者Maier, T, Clantin, B, Gruss, F, Dewitte, F, Delattre, A.S, Jacob-Dubuisson, F, Hiller, S, Villeret, V.
登録日2014-06-10
公開日2014-10-22
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Conserved Omp85 lid-lock structure and substrate recognition in FhaC
Nat Commun, 6, 2015
4QL0
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Crystal Structure Analysis of the Membrane Transporter FhaC (double mutant V169T, I176N)
分子名称: DI(HYDROXYETHYL)ETHER, Filamentous hemagglutinin transporter protein FhaC, HEXAETHYLENE GLYCOL, ...
著者Maier, T, Clantin, B, Gruss, F, Dewitte, F, Delattre, A.S, Jacob-Dubuisson, F, Hiller, S, Villeret, V.
登録日2014-06-10
公開日2015-06-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Conserved Omp85 lid-lock structure and substrate recognition in FhaC
Nat Commun, 6, 2015
2VZ9
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Crystal Structure of Mammalian Fatty Acid Synthase in complex with NADP
分子名称: FATTY ACID SYNTHASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Maier, T, Leibundgut, M, Ban, N.
登録日2008-07-31
公開日2008-09-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献The Crystal Structure of a Mammalian Fatty Acid Synthase.
Science, 321, 2008
2VZ8
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Crystal Structure of Mammalian Fatty Acid Synthase
分子名称: FATTY ACID SYNTHASE
著者Maier, T, Leibundgut, M, Ban, N.
登録日2008-07-31
公開日2008-09-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.219 Å)
主引用文献The Crystal Structure of a Mammalian Fatty Acid Synthase.
Science, 321, 2008
1O7A
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Human beta-Hexosaminidase B
分子名称: 1,2-ETHANEDIOL, 2-(acetylamido)-2-deoxy-D-glucono-1,5-lactone, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Maier, T, Strater, N, Schuette, C, Klingenstein, R, Sandhoff, K, Saenger, W.
登録日2002-10-29
公開日2003-10-23
最終更新日2020-11-18
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The X-Ray Crystal Structure of Human Beta-Hexosaminidase B Provides New Insights Into Sandhoff Disease
J.Mol.Biol., 328, 2003
2R1Q
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Crystal Structure of Iodinated Human Saposin D in Space Group C2221
分子名称: Proactivator polypeptide
著者Maier, T, Rossman, M, Saenger, W.
登録日2007-08-23
公開日2008-04-29
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
2RB3
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Crystal Structure of Human Saposin D
分子名称: GLYCEROL, Proactivator polypeptide, SULFATE ION
著者Maier, T, Rossman, M, Saenger, W.
登録日2007-09-18
公開日2008-04-29
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
2BJ6
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Crystal Structure of a decameric HNA-RNA hybrid
分子名称: 5'-R(*GP*GP*CP*AP*UP*UP*AP*CP*GP*GP)-3', SULFATE ION, SYNTHETIC HNA
著者Maier, T, Przylas, I, Straeter, N, Herdewijn, P, Saenger, W.
登録日2005-01-30
公開日2005-03-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Reinforced Hna Backbone Hydration in the Crystal Structure of a Decameric Hna/RNA Hybrid
J.Am.Chem.Soc., 127, 2005
2CF2
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Architecture of mammalian fatty acid synthase
分子名称: FATTY ACID SYNTHASE, DH DOMAIN, ER DOMAIN, ...
著者Maier, T, Jenni, S, Ban, N.
登録日2006-02-14
公開日2006-03-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Architecture of Mammalian Fatty Acid Synthase at 4.5 A Resolution.
Science, 311, 2006
4RQV
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Crystal structure of PDK1 in complex with ATP and the PIF-pocket ligand RS2
分子名称: 3-phosphoinositide-dependent protein kinase 1, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ...
著者Rettenmaier, T.J, Wells, J.A.
登録日2014-11-05
公開日2014-12-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.502 Å)
主引用文献A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1.
Proc.Natl.Acad.Sci.USA, 111, 2014
4RQK
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Crystal structure of PDK1 in complex with ATP and the PIF-pocket ligand RS1
分子名称: 3-phosphoinositide-dependent protein kinase 1, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Rettenmaier, T.J, Wells, J.A.
登録日2014-11-03
公開日2014-12-17
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1.
Proc.Natl.Acad.Sci.USA, 111, 2014
4RRV
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Crystal structure of PDK1 in complex with ATP and PIFtide
分子名称: 3-phosphoinositide-dependent protein kinase 1, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ...
著者Rettenmaier, T.J, Wells, J.A.
登録日2014-11-06
公開日2014-12-17
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.412 Å)
主引用文献A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1.
Proc.Natl.Acad.Sci.USA, 111, 2014
4XX9
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Crystal structure of PDK1 in complex with ATP and the PIF-pocket ligand RF4
分子名称: (2-{[2-(2,6-dimethylphenoxy)ethyl]sulfanyl}-1H-benzimidazol-1-yl)acetic acid, 3-phosphoinositide-dependent protein kinase 1, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Rettenmaier, T.J, Wells, J.A.
登録日2015-01-29
公開日2015-10-21
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Small-Molecule Allosteric Modulators of the Protein Kinase PDK1 from Structure-Based Docking.
J.Med.Chem., 58, 2015
5OOW
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Crystal structure of lobe II from the nucleotide binding domain of DnaK in complex with AMPPCP
分子名称: Chaperone protein DnaK, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
著者Jakob, R.P, Bauer, D, Meinhold, S, Stigler, J, Merkel, U, Maier, T, Rief, M, Zoldak, G.
登録日2017-08-09
公開日2018-04-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A folding nucleus and minimal ATP binding domain of Hsp70 identified by single-molecule force spectroscopy.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6ZWO
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cryo-EM structure of human mTOR complex 2, focused on one half
分子名称: ACETYL GROUP, INOSITOL HEXAKISPHOSPHATE, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Scaiola, A, Mangia, F, Imseng, S, Boehringer, D, Ban, N, Maier, T.
登録日2020-07-28
公開日2020-11-18
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献The 3.2- angstrom resolution structure of human mTORC2.
Sci Adv, 6, 2020
5JCQ
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Crystal structure of the FimH lectin domain from E.coli K12 in complex with methyl alpha-D-mannopyrannoside in spacegroup P21
分子名称: Protein FimH, SULFATE ION, methyl alpha-D-mannopyranoside
著者Jakob, R.P, Rabbani, S, Ernst, B, Maier, T.
登録日2016-04-15
公開日2017-05-10
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.602 Å)
主引用文献Crystal structure of the FimH lectin domain from E.coli K12 in complex with methyl alpha-D-mannopyrannoside in spacegroup P21
To Be Published
8CPQ
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Crystal structure of human protein disulfide isomerase PDIA6 domain b
分子名称: Protein disulfide-isomerase A6
著者Jakob, R.P, Leder, A.L, Hiller, S, Maier, T.
登録日2023-03-03
公開日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of human protein disulfide isomerase PDIA6 domain b
To Be Published
8CQR
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Cryo-EM structure of the NINJ1 filament
分子名称: Ninjurin-1
著者Degen, M.D, Hiller, S.H, Maier, T.M.
登録日2023-03-07
公開日2023-05-17
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis of NINJ1-mediated plasma membrane rupture in cell death.
Nature, 618, 2023
6YL3
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High resolution cryo-EM structure of urease from the pathogen Yersinia enterocolitica
分子名称: NICKEL (II) ION, Urease subunit alpha, Urease subunit beta, ...
著者Righetto, R.D, Anton, L, Adaixo, R, Jakob, R, Zivanov, J, Mahi, M.A, Ringler, P, Schwede, T, Maier, T, Stahlberg, H.
登録日2020-04-06
公開日2020-05-06
最終更新日2020-10-21
実験手法ELECTRON MICROSCOPY (1.98 Å)
主引用文献High-resolution cryo-EM structure of urease from the pathogen Yersinia enterocolitica.
Nat Commun, 11, 2020
3J9G
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Atomic model of the VipA/VipB, the type six secretion system contractile sheath of Vibrio cholerae from cryo-EM
分子名称: VipA, VipB
著者Kudryashev, M, Wang, R.Y.-R, Brackmann, M, Scherer, S, Maier, T, Baker, D, DiMaio, F, Stahlberg, H, Egelman, E.H, Basler, M.
登録日2015-01-16
公開日2015-03-11
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of the Type VI Secretion System Contractile Sheath.
Cell(Cambridge,Mass.), 160, 2015
7R1V
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Crystal structure of E.coli BamA beta-barrel in complex with dynobactin A
分子名称: Dynobactin A, Outer membrane protein assembly factor BamA
著者Jakob, R.P, Hiller, S, Maier, T.
登録日2022-02-03
公開日2022-09-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Computational identification of a systemic antibiotic for gram-negative bacteria.
Nat Microbiol, 7, 2022
8R5M
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E-selectin complexed with glycomimetic ligand DS0567
分子名称: (2~{S})-3-cyclohexyl-2-[(2~{R},3~{R},4~{S},5~{S},6~{R})-2-[(1~{R},2~{R},3~{S})-3-ethyl-2-[(2~{S},3~{S},4~{R},5~{S},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-cyclohexyl]oxy-6-(hydroxymethyl)-5-oxidanyl-3-(phenylcarbonyloxy)oxan-4-yl]oxy-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Jakob, R.P, Ernst, B, Maier, T.
登録日2023-11-17
公開日2024-10-23
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Analogues of the pan-selectin antagonist rivipansel (GMI-1070).
Eur.J.Med.Chem., 272, 2024
8R5L
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E-selectin complexed with glycomimetic ligand BW850
分子名称: (2~{S})-3-cyclohexyl-2-[(2~{R},3~{R},4~{S},5~{S},6~{R})-2-[(1~{R},2~{R},3~{S},5~{R})-3-ethyl-2-[(2~{S},3~{S},4~{R},5~{S},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5-[3-[1-[3-oxidanylidene-3-[(3,6,8-trisulfonaphthalen-1-yl)amino]propyl]-1,2,3-triazol-4-yl]propylcarbamoyl]cyclohexyl]oxy-6-(hydroxymethyl)-5-oxidanyl-3-(phenylcarbonyloxy)oxan-4-yl]oxy-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Jakob, R.P, Ernst, B, Maier, T.
登録日2023-11-17
公開日2024-10-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Analogues of the pan-selectin antagonist rivipansel (GMI-1070).
Eur.J.Med.Chem., 272, 2024
6SWR
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Crystal structure of the lysosomal potassium channel MtTMEM175 T38A mutant soaked with zinc
分子名称: DODECYL-BETA-D-MALTOSIDE, Nanobody, Maltose/maltodextrin-binding periplasmic protein,Maltodextrin-binding protein,Maltose/maltodextrin-binding periplasmic protein, ...
著者Brunner, J.D, Jakob, R.P, Schulze, T, Neldner, Y, Moroni, A, Thiel, G, Maier, T, Schenck, S.
登録日2019-09-23
公開日2020-04-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for ion selectivity in TMEM175 K + channels.
Elife, 9, 2020
2QYP
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Orthorhombic Crystal Structure of Human Saposin C Dimer in Open Conformation
分子名称: Proactivator polypeptide
著者Rossmann, M, Saenger, W, Maier, T.
登録日2007-08-15
公開日2008-04-29
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008

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