3M1D
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![BU of 3m1d by Molmil](/molmil-images/mine/3m1d) | Structure of BIR1 from cIAP1 | Descriptor: | Baculoviral IAP repeat-containing protein 2, ZINC ION | Authors: | Mace, P.D, Day, C.L. | Deposit date: | 2010-03-04 | Release date: | 2010-05-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Asymmetric recruitment of cIAPs by TRAF2 J.Mol.Biol., 400, 2010
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2VJF
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![BU of 2vjf by Molmil](/molmil-images/mine/2vjf) | Crystal Structure of the MDM2-MDMX RING Domain Heterodimer | Descriptor: | CITRATE ANION, E3 UBIQUITIN-PROTEIN LIGASE MDM2, MDM4 PROTEIN, ... | Authors: | Mace, P.D, Linke, K, Smith, C.A, Day, C.L. | Deposit date: | 2007-12-10 | Release date: | 2008-05-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the Mdm2/Mdmx Ring Domain Heterodimer Reveals Dimerization is Required for Their Ubiquitylation in Trans. Cell Death Differ., 15, 2008
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2VJE
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![BU of 2vje by Molmil](/molmil-images/mine/2vje) | Crystal Structure of the MDM2-MDMX RING Domain Heterodimer | Descriptor: | CITRATE ANION, E3 UBIQUITIN-PROTEIN LIGASE MDM2, MDM4 PROTEIN, ... | Authors: | Mace, P.D, Linke, K, Smith, C.A, Day, C.L. | Deposit date: | 2007-12-10 | Release date: | 2008-05-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans. Cell Death Differ., 15, 2008
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4IZ5
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![BU of 4iz5 by Molmil](/molmil-images/mine/4iz5) | Structure of the complex between ERK2 phosphomimetic mutant and PEA-15 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Astrocytic phosphoprotein PEA-15, Mitogen-activated protein kinase 1, ... | Authors: | Mace, P.D, Robinson, H, Riedl, S.J. | Deposit date: | 2013-01-29 | Release date: | 2013-04-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK. Nat Commun, 4, 2013
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4IZ7
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![BU of 4iz7 by Molmil](/molmil-images/mine/4iz7) | |
4IZA
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![BU of 4iza by Molmil](/molmil-images/mine/4iza) | |
2HLR
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![BU of 2hlr by Molmil](/molmil-images/mine/2hlr) | |
2HLQ
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![BU of 2hlq by Molmil](/molmil-images/mine/2hlq) | |
3T6G
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![BU of 3t6g by Molmil](/molmil-images/mine/3t6g) | |
3T6A
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![BU of 3t6a by Molmil](/molmil-images/mine/3t6a) | Structure of the C-terminal domain of BCAR3 | Descriptor: | (20S)-2,5,8,11,14,17-HEXAMETHYL-3,6,9,12,15,18-HEXAOXAHENICOSANE-1,20-DIOL, Breast cancer anti-estrogen resistance protein 3, UNKNOWN ATOM OR ION | Authors: | Mace, P.D, Robinson, H, Riedl, S.J. | Deposit date: | 2011-07-28 | Release date: | 2011-11-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | NSP-Cas protein structures reveal a promiscuous interaction module in cell signaling. Nat.Struct.Mol.Biol., 18, 2011
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3EB5
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![BU of 3eb5 by Molmil](/molmil-images/mine/3eb5) | Structure of the cIAP2 RING domain | Descriptor: | Baculoviral IAP repeat-containing protein 3, SODIUM ION, ZINC ION | Authors: | Mace, P.D, Linke, K, Smith, C.A, Day, C.L. | Deposit date: | 2008-08-27 | Release date: | 2008-09-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitment. J.Biol.Chem., 283, 2008
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3EB6
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![BU of 3eb6 by Molmil](/molmil-images/mine/3eb6) | Structure of the cIAP2 RING domain bound to UbcH5b | Descriptor: | Baculoviral IAP repeat-containing protein 3, Ubiquitin-conjugating enzyme E2 D2, ZINC ION | Authors: | Mace, P.D, Linke, K, Schumacher, F.-R, Smith, C.A, Day, C.L. | Deposit date: | 2008-08-27 | Release date: | 2008-09-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structures of the cIAP2 RING Domain Reveal Conformational Changes Associated with Ubiquitin-conjugating Enzyme (E2) Recruitment. J.Biol.Chem., 283, 2008
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5CEM
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![BU of 5cem by Molmil](/molmil-images/mine/5cem) | |
5CEK
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![BU of 5cek by Molmil](/molmil-images/mine/5cek) | |
5ULM
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![BU of 5ulm by Molmil](/molmil-images/mine/5ulm) | |
4W50
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![BU of 4w50 by Molmil](/molmil-images/mine/4w50) | Structure of the EphA4 LBD in complex with peptide | Descriptor: | 1,3-BUTANEDIOL, APY peptide, Ephrin type-A receptor 4, ... | Authors: | Lechtenberg, B.C, Mace, P.D, Riedl, S.J. | Deposit date: | 2014-08-16 | Release date: | 2014-10-08 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Development and Structural Analysis of a Nanomolar Cyclic Peptide Antagonist for the EphA4 Receptor. Acs Chem.Biol., 9, 2014
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4W4Z
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![BU of 4w4z by Molmil](/molmil-images/mine/4w4z) | Structure of the EphA4 LBD in complex with peptide | Descriptor: | APY-bAla8.am peptide, Ephrin type-A receptor 4, GLYCEROL, ... | Authors: | Lechtenberg, B.C, Mace, P.D, Riedl, S.J. | Deposit date: | 2014-08-15 | Release date: | 2014-10-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Development and Structural Analysis of a Nanomolar Cyclic Peptide Antagonist for the EphA4 Receptor. Acs Chem.Biol., 9, 2014
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7UPM
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![BU of 7upm by Molmil](/molmil-images/mine/7upm) | |
5EDV
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![BU of 5edv by Molmil](/molmil-images/mine/5edv) | Structure of the HOIP-RBR/UbcH5B~ubiquitin transfer complex | Descriptor: | E3 ubiquitin-protein ligase RNF31, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D2, ... | Authors: | Lechtenberg, B.C, Mace, P.D, Sanishvili, R, Riedl, S.J. | Deposit date: | 2015-10-22 | Release date: | 2016-01-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.48 Å) | Cite: | Structure of a HOIP/E2~ubiquitin complex reveals RBR E3 ligase mechanism and regulation. Nature, 529, 2016
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5D0I
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![BU of 5d0i by Molmil](/molmil-images/mine/5d0i) | Structure of RING finger protein 165 | Descriptor: | RING finger protein 165, SULFATE ION, ZINC ION | Authors: | Wright, J.D, Day, C.L, Mace, P.D. | Deposit date: | 2015-08-03 | Release date: | 2015-12-09 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity. Nat.Struct.Mol.Biol., 23, 2016
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5D0M
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![BU of 5d0m by Molmil](/molmil-images/mine/5d0m) | Structure of UbE2D2:RNF165:Ub complex | Descriptor: | PHOSPHATE ION, Polyubiquitin-B, RING finger protein 165, ... | Authors: | Wright, J.D, Day, C.L, Mace, P.D. | Deposit date: | 2015-08-03 | Release date: | 2015-12-09 | Last modified: | 2016-01-20 | Method: | X-RAY DIFFRACTION (1.913 Å) | Cite: | Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity. Nat.Struct.Mol.Biol., 23, 2016
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5D0K
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![BU of 5d0k by Molmil](/molmil-images/mine/5d0k) | Structure of UbE2D2:RNF165:Ub complex | Descriptor: | Polyubiquitin-B, RING finger protein 165, Ubiquitin-conjugating enzyme E2 D2, ... | Authors: | Wright, J.D, Day, C.L, Mace, P.D. | Deposit date: | 2015-08-03 | Release date: | 2015-12-09 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity. Nat.Struct.Mol.Biol., 23, 2016
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7R70
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![BU of 7r70 by Molmil](/molmil-images/mine/7r70) | Crystal Structure of the UbArk2C fusion protein | Descriptor: | GLYCEROL, Ubiquitin,E3 ubiquitin-protein ligase RNF165, ZINC ION | Authors: | Paluda, A, Middleton, A.J, Mace, P.D, Day, C.L. | Deposit date: | 2021-06-24 | Release date: | 2022-03-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.499 Å) | Cite: | Ubiquitin and a charged loop regulate the ubiquitin E3 ligase activity of Ark2C. Nat Commun, 13, 2022
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7R71
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![BU of 7r71 by Molmil](/molmil-images/mine/7r71) | Crystal Structure of the UbArk2C-UbcH5b~Ub complex | Descriptor: | Ubiquitin, Ubiquitin,E3 ubiquitin-protein ligase RNF165, Ubiquitin-conjugating enzyme E2 D2, ... | Authors: | Paluda, A, Middleton, A.J, Mace, P.D, Day, C.L. | Deposit date: | 2021-06-24 | Release date: | 2022-03-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Ubiquitin and a charged loop regulate the ubiquitin E3 ligase activity of Ark2C. Nat Commun, 13, 2022
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6CGA
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![BU of 6cga by Molmil](/molmil-images/mine/6cga) | Structure of the PR-DUB complex | Descriptor: | Polycomb protein Asx, Ubiquitin carboxyl-terminal hydrolase calypso | Authors: | Foglizzo, M, Middleton, A.J, Day, C.L, Mace, P.D. | Deposit date: | 2018-02-19 | Release date: | 2018-10-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | A bidentate Polycomb Repressive-Deubiquitinase complex is required for efficient activity on nucleosomes. Nat Commun, 9, 2018
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