7UPM

Tribbles (TRIB2) pseudokinase bound to nanobody Nb4.103

Summary for 7UPM

• Entry DOI: 10.2210/pdb7upm/pdb
• Descriptor: Tribbles homolog 2, Nb4.103 Nanobody (3 entities in total)
• Functional Keywords: tribbles, psuedokinase, trb2, trib2, nanobody, signaling protein, signaling protein-immune system complex, signaling protein/immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 42991.62

Authors

Jamieson, S.A.,Mace, P.D. (deposition date: 2022-04-15, release date: 2022-09-14, Last modification date: 2023-10-18)

• Primary citation: Jamieson, S.A.,Pudjihartono, M.,Horne, C.R.,Viloria, J.S.,Dunlop, J.L.,McMillan, H.D.,Day, R.C.,Keeshan, K.,Murphy, J.M.,Mace, P.D.; Nanobodies identify an activated state of the TRIB2 pseudokinase.; Structure, 30:1518-, 2022; PubMed: 36108635; DOI: 10.1016/j.str.2022.08.006

Experimental method

X-RAY DIFFRACTION (2.7 Å)