3T6G

Structure of the complex between NSP3 (SHEP1) and p130Cas

Summary for 3T6G

Entry DOI	10.2210/pdb3t6g/pdb
Related	3T6A
Descriptor	SH2 domain-containing protein 3C, Breast cancer anti-estrogen resistance protein 1, ACETATE ION, ... (4 entities in total)
Functional Keywords	cdc25-homology domain, gtpase exchange factor, focal-adhesion targeting domain, signaling protein, cell adhesion
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm (By similarity): Q8N5H7 Cell junction, focal adhesion: P56945
Total number of polymer chains	4
Total formula weight	125155.88
Authors	Mace, P.D.,Robinson, H.,Riedl, S.J. (deposition date: 2011-07-28, release date: 2011-11-23, Last modification date: 2024-02-28)
Primary citation	Mace, P.D.,Wallez, Y.,Dobaczewska, M.K.,Lee, J.J.,Robinson, H.,Pasquale, E.B.,Riedl, S.J. NSP-Cas protein structures reveal a promiscuous interaction module in cell signaling. Nat.Struct.Mol.Biol., 18:1381-1387, 2011 Cited by PubMed: 22081014 DOI: 10.1038/nsmb.2152 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation