5ULM
Structure of the ASK1 central regulatory region
Summary for 5ULM
Entry DOI | 10.2210/pdb5ulm/pdb |
Descriptor | Mitogen-activated protein kinase kinase kinase 5, GLYCEROL (3 entities in total) |
Functional Keywords | ask1, pleckstrin homology, tetratricopeptide, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: Q99683 |
Total number of polymer chains | 2 |
Total formula weight | 90741.90 |
Authors | Mace, P.D.,Kumar, A.,Caradoc-Davies, T.T. (deposition date: 2017-01-24, release date: 2017-03-01, Last modification date: 2024-03-06) |
Primary citation | Weijman, J.F.,Kumar, A.,Jamieson, S.A.,King, C.M.,Caradoc-Davies, T.T.,Ledgerwood, E.C.,Murphy, J.M.,Mace, P.D. Structural basis of autoregulatory scaffolding by apoptosis signal-regulating kinase 1. Proc. Natl. Acad. Sci. U.S.A., 114:E2096-E2105, 2017 Cited by PubMed: 28242696DOI: 10.1073/pnas.1620813114 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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