Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 52230 results

4A6N
DownloadVisualize
BU of 4a6n by Molmil
STRUCTURE OF THE TETRACYCLINE DEGRADING MONOOXYGENASE TETX IN COMPLEX WITH TIGECYCLINE
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, TETX2 PROTEIN, ...
Authors:Volkers, G, Palm, G.J, Weiss, M.S, Hinrichs, W.
Deposit date:2011-11-07
Release date:2012-11-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Putative Dioxygen-Binding Sites and Recognition of Tigecycline and Minocycline in the Tetracycline-Degrading Monooxygenase Tetx
Acta Crystallogr.,Sect.D, 69, 2013
3M11
DownloadVisualize
BU of 3m11 by Molmil
Crystal Structure of Aurora A Kinase complexed with inhibitor
Descriptor: 1-(4-{2-[(5,6-diphenylfuro[2,3-d]pyrimidin-4-yl)amino]ethyl}phenyl)-3-phenylurea, Serine/threonine-protein kinase 6
Authors:Wu, J.S, Leou, J.S, Coumar, M.S, Hsieh, H.P, Wu, S.Y.
Deposit date:2010-03-03
Release date:2011-03-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Fast-forwarding hit to lead: aurora and epidermal growth factor receptor kinase inhibitor lead identification
J.Med.Chem., 53, 2010
1XXX
DownloadVisualize
BU of 1xxx by Molmil
Crystal structure of Dihydrodipicolinate Synthase (DapA, Rv2753c) from Mycobacterium tuberculosis
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, Dihydrodipicolinate synthase, ...
Authors:Kefala, G, Panjikar, S, Janowski, R, Weiss, M.S, TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-11-09
Release date:2006-02-14
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis.
Biochem.J., 411, 2008
3VOS
DownloadVisualize
BU of 3vos by Molmil
Crystal structure of Aspartate semialdehyde dehydrogenase Complexed With glycerol and sulfate From Mycobacterium tuberculosis H37Rv
Descriptor: Aspartate-semialdehyde dehydrogenase, GLYCEROL, SULFATE ION
Authors:Vyas, R, Tewari, R, Weiss, M.S, Karthikeyan, S.
Deposit date:2012-02-07
Release date:2012-05-30
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Structures of ternary complexes of aspartate-semialdehyde dehydrogenase (Rv3708c) from Mycobacterium tuberculosis H37Rv
Acta Crystallogr.,Sect.D, 68, 2012
3L1U
DownloadVisualize
BU of 3l1u by Molmil
Crystal structure of Calcium-bound GmhB from E. coli.
Descriptor: CALCIUM ION, D,D-heptose 1,7-bisphosphate phosphatase, ZINC ION
Authors:Sugiman-Marangos, S.N, Junop, M.S.
Deposit date:2009-12-14
Release date:2010-01-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural and kinetic characterization of the LPS biosynthetic enzyme D-alpha,beta-D-heptose-1,7-bisphosphate phosphatase (GmhB) from Escherichia coli.
Biochemistry, 49, 2010
3L35
DownloadVisualize
BU of 3l35 by Molmil
PIE12 D-peptide against HIV entry
Descriptor: GP41 N-PEPTIDE, HIV ENTRY INHIBITOR PIE12
Authors:Welch, B.D, Redman, J.S, Paul, S, Whitby, F.G, Weinstock, M.T, Reeves, J.D, Lie, Y.S, Eckert, D.M, Hill, C.P, Root, M.J, Kay, M.S.
Deposit date:2009-12-16
Release date:2010-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Design of a potent D-peptide HIV-1 entry inhibitor with a strong barrier to resistance.
J.Virol., 84, 2010
1L9E
DownloadVisualize
BU of 1l9e by Molmil
Role of Histidine 269 in Catalysis by Monomeric Sarcosine Oxidase
Descriptor: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, IMIDAZOLE, ...
Authors:Zhao, G, Song, H, Chen, Z.-w, Mathews, F.S, Jorns, M.S.
Deposit date:2002-03-22
Release date:2002-08-30
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Monomeric sarcosine oxidase: role of histidine 269 in catalysis.
Biochemistry, 41, 2002
2WOI
DownloadVisualize
BU of 2woi by Molmil
Trypanothione reductase from Trypanosoma brucei
Descriptor: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, SODIUM ION, ...
Authors:Alphey, M.S, Fairlamb, A.H.
Deposit date:2009-07-24
Release date:2010-08-04
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Dihydroquinazolines as a Novel Class of Trypanosoma Brucei Trypanothione Reductase Inhibitors: Discovery, Synthesis, and Characterization of Their Binding Mode by Protein Crystallography.
J.Med.Chem., 54, 2011
5WS6
DownloadVisualize
BU of 5ws6 by Molmil
Native XFEL structure of Photosystem II (preflash two-flash dataset
Descriptor: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
Authors:Suga, M, Shen, J.R.
Deposit date:2016-12-05
Release date:2017-03-15
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Light-induced structural changes and the site of O=O bond formation in PSII caught by XFEL.
Nature, 543, 2017
3M58
DownloadVisualize
BU of 3m58 by Molmil
SET7/9 Y245A in complex with TAF10-K189me1 peptide and AdoHcy
Descriptor: Histone-lysine N-methyltransferase SETD7, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ...
Authors:Del Rizzo, P.A, Couture, J.-F, Roiko, M.S, Strunk, B.S, Brunzelle, J.S, Dirk, L.M, Houtz, R.L, Trievel, R.C.
Deposit date:2010-03-12
Release date:2010-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:SET7/9 catalytic mutants reveal the role of active site water molecules in lysine multiple methylation.
J.Biol.Chem., 285, 2010
3UK3
DownloadVisualize
BU of 3uk3 by Molmil
Crystal structure of ZNF217 bound to DNA
Descriptor: 5'-D(*AP*AP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP*CP*A)-3', 5'-D(*TP*TP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP*CP*A)-3', CHLORIDE ION, ...
Authors:Vandevenne, M.S, Jacques, D.A, Guss, J.M, Mackay, J.P.
Deposit date:2011-11-08
Release date:2012-12-05
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Rediscovering DNA recognition by classical Zinc Fingers.
To be Published
3M5A
DownloadVisualize
BU of 3m5a by Molmil
SET7/9 Y245A in complex with TAF10-K189me3 peptide and AdoHcy
Descriptor: COBALT (II) ION, GLYCEROL, Histone-lysine N-methyltransferase SETD7, ...
Authors:Del Rizzo, P.A, Couture, J.-F, Roiko, M.S, Strunk, B.S, Brunzelle, J.S, Dirk, L.M, Houtz, R.L, Trievel, R.C.
Deposit date:2010-03-12
Release date:2010-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:SET7/9 catalytic mutants reveal the role of active site water molecules in lysine multiple methylation.
J.Biol.Chem., 285, 2010
3UWK
DownloadVisualize
BU of 3uwk by Molmil
Structure Guided Development of Novel Thymidine Mimetics targeting Pseudomonas aeruginosa Thymidylate Kinase: from Hit to Lead Generation
Descriptor: 1-methyl-6-phenyl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one, MAGNESIUM ION, Thymidylate kinase
Authors:Choi, J.Y, Plummer, M.S, Starr, J, Desbonnet, C.R, Soutter, H.H, Chang, J, Miller, J.R, Dillman, K, Miller, A.A, Roush, W.R.
Deposit date:2011-12-02
Release date:2012-02-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structure guided development of novel thymidine mimetics targeting Pseudomonas aeruginosa thymidylate kinase: from hit to lead generation.
J.Med.Chem., 55, 2012
3UWO
DownloadVisualize
BU of 3uwo by Molmil
Structure Guided Development of Novel Thymidine Mimetics targeting Pseudomonas aeruginosa Thymidylate Kinase: from Hit to Lead Generation
Descriptor: 3-(1-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-6-yl)benzamide, Thymidylate kinase
Authors:Choi, J.Y, Plummer, M.S, Starr, J, Desbonnet, C.R, Soutter, H.H, Chang, J, Miller, J.R, Dillman, K, Miller, A.A, Roush, W.R.
Deposit date:2011-12-02
Release date:2012-02-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure guided development of novel thymidine mimetics targeting Pseudomonas aeruginosa thymidylate kinase: from hit to lead generation.
J.Med.Chem., 55, 2012
1XPX
DownloadVisualize
BU of 1xpx by Molmil
Structural basis of prospero-DNA interaction; implications for transcription regulation in developing cells
Descriptor: 5'-D(*AP*GP*CP*AP*TP*GP*CP*CP*TP*G)-3', 5'-D(*CP*AP*GP*GP*CP*AP*TP*GP*CP*T)-3', Protein prospero
Authors:Yousef, M.S, Matthews, B.W.
Deposit date:2004-10-09
Release date:2005-05-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis of Prospero-DNA Interaction: Implications for Transcription Regulationin Developing Cells.
STRUCTURE, 13, 2005
2Z81
DownloadVisualize
BU of 2z81 by Molmil
Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide
Descriptor: (2R)-3-{[(2S)-3-HYDROXY-2-(PALMITOYLAMINO)PROPYL]THIO}PROPANE-1,2-DIYL DIHEXADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 2, ...
Authors:Lee, J.O, Jin, M.S, Kim, S.E, Heo, J.Y.
Deposit date:2007-08-30
Release date:2007-10-02
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide
Cell(Cambridge,Mass.), 130, 2007
1X76
DownloadVisualize
BU of 1x76 by Molmil
CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR BETA COMPLEXED WITH WAY-697
Descriptor: 5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-CARBONITRILE, Estrogen receptor beta, STEROID RECEPTOR COACTIVATOR-1
Authors:Manas, E.S, Unwalla, R.J, Xu, Z.B, Malamas, M.S, Miller, C.P, Harris, H.A, Hsiao, C, Akopian, T, Hum, W.T, Malakian, K, Wolfrom, S, Bapat, A, Bhat, R.A, Stahl, M.L, Somers, W.S, Alvarez, J.C.
Deposit date:2004-08-13
Release date:2005-03-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-Based Design of Estrogen Receptor-Beta Selective Ligands
J.Am.Chem.Soc., 126, 2004
1X7E
DownloadVisualize
BU of 1x7e by Molmil
CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR ALPHA COMPLEXED WITH WAY-244
Descriptor: Estrogen receptor 1 (alpha), [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE, steroid receptor coactivator-3
Authors:Manas, E.S, Unwalla, R.J, Xu, Z.B, Malamas, M.S, Miller, C.P, Harris, H.A, Hsiao, C, Akopian, T, Hum, W.T, Malakian, K, Wolfrom, S, Bapat, A, Bhat, R.A, Stahl, M.L, Somers, W.S, Alvarez, J.C.
Deposit date:2004-08-13
Release date:2005-03-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-Based Design of Estrogen Receptor-Beta Selective Ligands
J.Am.Chem.Soc., 126, 2004
3M57
DownloadVisualize
BU of 3m57 by Molmil
SET7/9 Y245A in complex with TAF10 peptide and AdoHcy
Descriptor: GLYCEROL, Histone-lysine N-methyltransferase SETD7, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Del Rizzo, P.A, Couture, J.-F, Roiko, M.S, Strunk, B.S, Brunzelle, J.S, Dirk, L.M, Houtz, R.L, Trievel, R.C.
Deposit date:2010-03-12
Release date:2010-07-28
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:SET7/9 catalytic mutants reveal the role of active site water molecules in lysine multiple methylation.
J.Biol.Chem., 285, 2010
1XCB
DownloadVisualize
BU of 1xcb by Molmil
X-ray Structure of a Rex-Family Repressor/NADH Complex from Thermus Aquaticus
Descriptor: CALCIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Redox-sensing transcriptional repressor rex
Authors:Sickmier, E.A, Brekasis, D, Paranawithana, S, Bonanno, J.B, Burley, S.K, Paget, M.S, Kielkopf, C.L, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2004-09-01
Release date:2004-09-28
Last modified:2021-02-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:X-Ray Structure of a Rex-Family Repressor/NADH Complex: Insights into the Mechanism of Redox Sensing
Structure, 13, 2005
1XOY
DownloadVisualize
BU of 1xoy by Molmil
Solution structure of At3g04780.1, an Arabidopsis ortholog of the C-terminal domain of human thioredoxin-like protein
Descriptor: hypothetical protein At3g04780.1
Authors:Song, J, Robert, C.T, Lee, M.S, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2004-10-07
Release date:2004-10-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of At3g04780.1-des15, an Arabidopsis thaliana ortholog of the C-terminal domain of human thioredoxin-like protein.
Protein Sci., 14, 2005
2Z7X
DownloadVisualize
BU of 2z7x by Molmil
Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide
Descriptor: (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, ...
Authors:Lee, J.O, Jin, M.S, Kim, S.E, Heo, J.Y.
Deposit date:2007-08-29
Release date:2007-10-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide
Cell(Cambridge,Mass.), 130, 2007
1XA7
DownloadVisualize
BU of 1xa7 by Molmil
Crystal structure of the benzylpenicillin-acylated BlaR1 sensor domain from Staphylococcus aureus
Descriptor: OPEN FORM - PENICILLIN G, Regulatory protein BlaR1
Authors:Wilke, M.S, Hills, T.L, Zhang, H.Z, Chambers, H.F, Strynadka, N.C.
Deposit date:2004-08-25
Release date:2004-09-21
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of the Apo and penicillin-acylated forms of the BlaR1 beta-lactam sensor of Staphylococcus aureus.
J.Biol.Chem., 279, 2004
3MNN
DownloadVisualize
BU of 3mnn by Molmil
A Ruthenium Antitumour Agent Forms Specific Histone Protein Adducts in the Nucleosome Core
Descriptor: 1,3,5-triaza-7-phosphatricyclo[3.3.1.1~3,7~]decane, 1-methyl-4-(1-methylethyl)benzene, DNA (145-MER), ...
Authors:Ong, M.S, Davey, C.A.
Deposit date:2010-04-22
Release date:2011-04-06
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A ruthenium antimetastasis agent forms specific histone protein adducts in the nucleosome core
Chemistry, 17, 2011
2XU8
DownloadVisualize
BU of 2xu8 by Molmil
Structure of Pa1645
Descriptor: PA1645, SULFATE ION
Authors:Abdelli, W.B, Moynie, L, McMahon, S.A, Liu, H, Alphey, M.S, Naismith, J.H.
Deposit date:2010-10-15
Release date:2010-12-29
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:The Aeropath Project Targeting Pseudomonas Aeruginosa: Crystallographic Studies for Assessment of Potential Targets in Early-Stage Drug Discovery
Acta Crystallogr.,Sect.F, 69, 2013

227111

數據於2024-11-06公開中

PDB statisticsPDBj update infoContact PDBjnumon