4TLU
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4S39
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![BU of 4s39 by Molmil](/molmil-images/mine/4s39) | IspG in complex with HMBPP | Descriptor: | (2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate, 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, GLYCEROL, ... | Authors: | Quitterer, F, Frank, A, Wang, K, Guodong, R, O'Dowd, B, Li, J, Guerra, F, Abdel-Azeim, S, Bacher, A, Eppinger, J, Oldfield, E, Groll, M. | Deposit date: | 2015-01-26 | Release date: | 2015-04-29 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Atomic-Resolution Structures of Discrete Stages on the Reaction Coordinate of the [Fe4S4] Enzyme IspG (GcpE). J.Mol.Biol., 427, 2015
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7WTC
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![BU of 7wtc by Molmil](/molmil-images/mine/7wtc) | Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the ground state | Descriptor: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, Pyruvate carboxylase, ... | Authors: | Chai, P, Lan, P, Wu, J, Lei, M. | Deposit date: | 2022-02-04 | Release date: | 2022-11-09 | Last modified: | 2022-11-16 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
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4TNG
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7WTB
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![BU of 7wtb by Molmil](/molmil-images/mine/7wtb) | Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA | Descriptor: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Chai, P, Lan, P, Wu, J, Lei, M. | Deposit date: | 2022-02-04 | Release date: | 2022-11-09 | Last modified: | 2022-11-16 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
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4TQ6
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![BU of 4tq6 by Molmil](/molmil-images/mine/4tq6) | Structure of a UbiA homolog from Archaeoglobus fulgidus bound to Cd2+ | Descriptor: | CADMIUM ION, prenyltransferase | Authors: | Huang, H, Levin, E.J, Bai, Y, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS) | Deposit date: | 2014-06-10 | Release date: | 2014-07-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.0678 Å) | Cite: | Structure of a Membrane-Embedded Prenyltransferase Homologous to UBIAD1. Plos Biol., 12, 2014
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4TT4
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![BU of 4tt4 by Molmil](/molmil-images/mine/4tt4) | Crystal structure of ATAD2A bromodomain complexed with H3(1-21)K14Ac peptide | Descriptor: | ATPase family AAA domain-containing protein 2, CHLORIDE ION, Histone H3(1-21)K4Ac, ... | Authors: | Poncet-Montange, G, Zhan, Y, Bardenhagen, J, Petrocchi, A, Leo, E, Shi, X, Lee, G, Leonard, P, Geck Do, M, Cardozo, M, Palmer, W, Andersen, J, Jones, P, Ladbury, J. | Deposit date: | 2014-06-19 | Release date: | 2014-12-24 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2. Biochem.J., 466, 2015
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4TQ5
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![BU of 4tq5 by Molmil](/molmil-images/mine/4tq5) | Structure of a UbiA homolog from Archaeoglobus fulgidus | Descriptor: | octyl beta-D-glucopyranoside, prenyltransferase | Authors: | Huang, H, Levin, E.J, Bai, Y, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS) | Deposit date: | 2014-06-10 | Release date: | 2014-07-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.2023 Å) | Cite: | Structure of a Membrane-Embedded Prenyltransferase Homologous to UBIAD1. Plos Biol., 12, 2014
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6LXG
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![BU of 6lxg by Molmil](/molmil-images/mine/6lxg) | NMR solution structure of regulatory ACT domain of the Mycobacterium tuberculosis Rel protein | Descriptor: | GTP pyrophosphokinase | Authors: | Shin, J, Singal, B, Manimekalai, M.S.S, Gruber, G. | Deposit date: | 2020-02-11 | Release date: | 2020-11-04 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Atomic structure of, and valine binding to the regulatory ACT domain of the Mycobacterium tuberculosis Rel protein. Febs J., 288, 2021
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4TTU
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![BU of 4ttu by Molmil](/molmil-images/mine/4ttu) | N-terminally truncated dextransucrase DSR-E from Leuconostoc mesenteroides NRRL B-1299 in complex with isomaltotriose | Descriptor: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, Dextransucrase, ... | Authors: | Brison, Y, Remaud-Simeon, M, Mourey, L, Tranier, S. | Deposit date: | 2014-06-23 | Release date: | 2015-07-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Structural Insights into the Carbohydrate Binding Ability of an alpha-(12) Branching Sucrase from Glycoside Hydrolase Family 70. J.Biol.Chem., 291, 2016
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7CYI
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![BU of 7cyi by Molmil](/molmil-images/mine/7cyi) | Crystal structure of Alcohol dehydrogenase 1 from Artemisia annua | Descriptor: | Alcohol dehydrogenase 1, ZINC ION | Authors: | Feng, X, Fan, S, Lv, G, Li, M, Wu, G, Jin, Y, Yang, Z. | Deposit date: | 2020-09-03 | Release date: | 2021-09-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Crystal structure of Alcohol dehydrogenase 1 from Artemisia annua To Be Published
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4RNL
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![BU of 4rnl by Molmil](/molmil-images/mine/4rnl) | The crystal structure of a possible galactose mutarotase from Streptomyces platensis subsp. rosaceus | Descriptor: | GLYCEROL, PHOSPHATE ION, possible galactose mutarotase | Authors: | Tan, K, Li, H, Endres, M, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2014-10-24 | Release date: | 2014-11-26 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The crystal structure of a possible galactose mutarotase from Streptomyces platensis subsp. rosaceus To be Published
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4OJG
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7DHS
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![BU of 7dhs by Molmil](/molmil-images/mine/7dhs) | Crystal Structure Analysis of the BRD4 | Descriptor: | 6-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(1R)-1-phenylethyl]benzo[cd]indol-2-one, Bromodomain-containing protein 4 | Authors: | Wu, T, Xiang, Q, Wang, C, Wu, C, Zhang, C, Zhang, M, Liu, Z, Zhang, Y, Xiao, L, Xu, Y. | Deposit date: | 2020-11-17 | Release date: | 2021-09-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Y06014 is a selective BET inhibitor for the treatment of prostate cancer. Acta Pharmacol.Sin., 42, 2021
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4RSO
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![BU of 4rso by Molmil](/molmil-images/mine/4rso) | The structure of the neurotropic AAVrh.8 viral vector | Descriptor: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, CHLORIDE ION, Capsid protein VP1, ... | Authors: | Halder, S, Van Vliet, K, Smith, J.K, McKenna, R, Wilson, J.M, Agbandje-McKenna, M. | Deposit date: | 2014-11-10 | Release date: | 2016-04-13 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structure of neurotropic adeno-associated virus AAVrh.8. J.Struct.Biol., 192, 2015
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4RT4
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![BU of 4rt4 by Molmil](/molmil-images/mine/4rt4) | Crystal structure of Dpy30 complexed with Bre2 | Descriptor: | Peptide from COMPASS component BRE2, Protein dpy-30 homolog | Authors: | Zhang, H.M, Li, M, Chang, W.R. | Deposit date: | 2014-11-12 | Release date: | 2015-10-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.997 Å) | Cite: | Structural implications of Dpy30 oligomerization for MLL/SET1 COMPASS H3K4 trimethylation Protein Cell, 6, 2015
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4RWZ
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![BU of 4rwz by Molmil](/molmil-images/mine/4rwz) | Crystal structure of the antibiotic-resistance methyltransferase Kmr | Descriptor: | Putative rRNA methyltransferase | Authors: | Savic, M. | Deposit date: | 2014-12-08 | Release date: | 2015-03-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.801 Å) | Cite: | 30S Subunit-Dependent Activation of the Sorangium cellulosum So ce56 Aminoglycoside Resistance-Conferring 16S rRNA Methyltransferase Kmr. Antimicrob.Agents Chemother., 59, 2015
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7W75
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7W76
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![BU of 7w76 by Molmil](/molmil-images/mine/7w76) | Crystal structure of the K. lactis Bre1 RBD in complex with Rad6, crystal form II | Descriptor: | E3 ubiquitin-protein ligase BRE1, GLYCEROL, SULFATE ION, ... | Authors: | Shi, M, Zhao, J, Xiang, S. | Deposit date: | 2021-12-03 | Release date: | 2023-03-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structural basis for the Rad6 activation by the Bre1 N-terminal domain. Elife, 12, 2023
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6YBV
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![BU of 6ybv by Molmil](/molmil-images/mine/6ybv) | Structure of a human 48S translational initiation complex - eIF2-TC | Descriptor: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit 3, ... | Authors: | Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V. | Deposit date: | 2020-03-17 | Release date: | 2020-09-16 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of a human 48Stranslational initiation complex. Science, 369, 2020
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4S3C
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![BU of 4s3c by Molmil](/molmil-images/mine/4s3c) | IspG in complex with Epoxide Intermediate | Descriptor: | (3S)-1,3-dihydroxy-4-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}-2-methylbut-2-ylium, carbokation intermediate, 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, ... | Authors: | Quitterer, F, Frank, A, Wang, K, Rao, G, O'Dowd, B, Li, J, Guerra, F, Abdel-Azeim, S, Bacher, A, Eppinger, J, Oldfield, E, Groll, M. | Deposit date: | 2015-01-26 | Release date: | 2015-05-06 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Atomic-Resolution Structures of Discrete Stages on the Reaction Coordinate of the [Fe4S4] Enzyme IspG (GcpE). J.Mol.Biol., 427, 2015
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4S1A
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![BU of 4s1a by Molmil](/molmil-images/mine/4s1a) | Crystal structure of a hypothetical protein Cthe_0052 from Ruminiclostridium thermocellum ATCC 27405 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CITRATE ANION, TETRAETHYLENE GLYCOL, ... | Authors: | Filippova, E.V, Wawrzak, Z, Minasov, G, Kiryukhina, O, Endres, M, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2015-01-09 | Release date: | 2015-01-28 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure of a hypothetical protein Cthe_0052 from Ruminiclostridium thermocellum ATCC27405 To be Published
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4S1P
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![BU of 4s1p by Molmil](/molmil-images/mine/4s1p) | Shel_16390 protein, a putative SGNH hydrolase from Slackia heliotrinireducens | Descriptor: | UNKNOWN LIGAND, Uncharacterized protein | Authors: | Osipiuk, J, Cuff, M.E, Wu, R, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2015-01-14 | Release date: | 2015-01-28 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Shel_16390 protein, a putative SGNH hydrolase from Slackia heliotrinireducens To be Published
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4TOB
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![BU of 4tob by Molmil](/molmil-images/mine/4tob) | 1.95A resolution structure of BfrB (Q151L) from Pseudomonas aeruginosa | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Bacterioferritin, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Lovell, S, Battaile, K.P, Yao, H, Kumar, R, Eshelman, K, Rivera, M. | Deposit date: | 2014-06-05 | Release date: | 2015-02-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Concerted motions networking pores and distant ferroxidase centers enable bacterioferritin function and iron traffic. Biochemistry, 54, 2015
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3D4X
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