6U0H
| Tubulin lattice of the ciliary doublet microtubule from Tetrahymena thermophila | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Ichikawa, M, Khalifa, A.A.Z, Vargas, J, Basu, K, Bui, K.H. | 登録日 | 2019-08-14 | 公開日 | 2019-09-25 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Tubulin lattice in cilia is in a stressed form regulated by microtubule inner proteins. Proc.Natl.Acad.Sci.USA, 116, 2019
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6U0U
| Protofilament Ribbon Flagellar Proteins Rib43a-L | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Ichikawa, M, Khalifa, A.A.Z, Vargas, J, Basu, K, Bui, K.H. | 登録日 | 2019-08-14 | 公開日 | 2019-09-25 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.16 Å) | 主引用文献 | Tubulin lattice in cilia is in a stressed form regulated by microtubule inner proteins. Proc.Natl.Acad.Sci.USA, 116, 2019
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6LQM
| Cryo-EM structure of a pre-60S ribosomal subunit - state C | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N. | 登録日 | 2020-01-14 | 公開日 | 2020-08-26 | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | 主引用文献 | Structural snapshots of human pre-60S ribosomal particles before and after nuclear export. Nat Commun, 11, 2020
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5HTD
| Recombinant bovine beta-lactoglobulin variant L1A/I2S with endogenous ligand (sBlgB#1) | 分子名称: | Beta-lactoglobulin, MYRISTIC ACID | 著者 | Loch, J.I, Bonarek, P, Tworzydlo, M, Polit, A, Hawro, B, Lach, A, Ludwin, E, Lewinski, K. | 登録日 | 2016-01-26 | 公開日 | 2016-07-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Engineered beta-Lactoglobulin Produced in E. coli: Purification, Biophysical and Structural Characterisation. Mol Biotechnol., 58, 2016
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5HTE
| Recombinant bovine beta-lactoglobulin variant L1A/I2S (sBlgB#2) | 分子名称: | Beta-lactoglobulin | 著者 | Loch, J.I, Bonarek, P, Tworzydlo, M, Polit, A, Hawro, B, Lach, A, Ludwin, E, Lewinski, K. | 登録日 | 2016-01-26 | 公開日 | 2016-07-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Engineered beta-Lactoglobulin Produced in E. coli: Purification, Biophysical and Structural Characterisation. Mol Biotechnol., 58, 2016
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7ZEV
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7ZEW
| Complex Cyp33-RRM : AAUAAA RNA | 分子名称: | Peptidyl-prolyl cis-trans isomerase E, RNA (5'-R(*AP*AP*UP*AP*AP*A)-3') | 著者 | Blatter, M, Allain, F, Meylan, C. | 登録日 | 2022-03-31 | 公開日 | 2022-04-13 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Sci Adv, 9, 2023
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7ZEZ
| Trimolecular complex Cyp33-RRMdelta alpha : MLL1-PHD3 : H3K4me3 | 分子名称: | Histone H3, Isoform 3 of Peptidyl-prolyl cis-trans isomerase E, MLL cleavage product N320, ... | 著者 | Blatter, M, Allain, F, Meylan, C. | 登録日 | 2022-03-31 | 公開日 | 2022-04-13 | 最終更新日 | 2023-05-03 | 実験手法 | SOLUTION NMR | 主引用文献 | RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Sci Adv, 9, 2023
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7NEL
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10MH
| TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH ADOHCY AND HEMIMETHYLATED DNA CONTAINING 5,6-DIHYDRO-5-AZACYTOSINE AT THE TARGET | 分子名称: | DNA (5'-D(P*CP*CP*AP*TP*GP*(5CM)P*GP*CP*TP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*AP*GP*5NCP*GP*CP*AP*TP*GP*G)-3'), PROTEIN (CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI), ... | 著者 | Sheikhnejad, G, Brank, A, Christman, J.K, Goddard, A, Alvarez, E, Ford Junior, H, Marquez, V.E, Marasco, C.J, Sufrin, J.R, O'Gara, M, Cheng, X. | 登録日 | 1998-08-10 | 公開日 | 1999-02-09 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Mechanism of inhibition of DNA (cytosine C5)-methyltransferases by oligodeoxyribonucleotides containing 5,6-dihydro-5-azacytosine. J.Mol.Biol., 285, 1999
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7NDO
| ER-PRS*(-) (L536S, L372R) in complex with raloxifene | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Estrogen receptor, ... | 著者 | Kriegel, M, Muller, Y.A. | 登録日 | 2021-02-02 | 公開日 | 2021-08-25 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A PROSS-designed extensively mutated estrogen receptor alpha variant displays enhanced thermal stability while retaining native allosteric regulation and structure. Sci Rep, 11, 2021
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7NFB
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6IBJ
| Copper binding protein from Laetisaria arvalis (LaX325) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Auxiliary activity CAZyme, COPPER (II) ION | 著者 | Frandsen, K.E.H, Tandrup, T, Labourel, A, Haon, M, Berrin, J.-G, Lo Leggio, L. | 登録日 | 2018-11-30 | 公開日 | 2019-11-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A fungal family of lytic polysaccharide monooxygenase-like copper proteins. Nat.Chem.Biol., 16, 2020
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6U3Y
| Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus | 分子名称: | ACETATE ION, Gamma-hemolysin subunit A, Panton-Valentine Leucocidin F, ... | 著者 | Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M. | 登録日 | 2019-08-22 | 公開日 | 2020-03-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence. J.Biol.Chem., 295, 2020
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1T49
| Allosteric Inhibition of Protein Tyrosine Phosphatase 1B | 分子名称: | 3-(3,5-DIBROMO-4-HYDROXY-BENZOYL)-2-ETHYL-BENZOFURAN-6-SULFONIC ACID (4-SULFAMOYL-PHENYL)-AMIDE, MAGNESIUM ION, Protein-tyrosine phosphatase, ... | 著者 | Wiesmann, C, Barr, K.J, Kung, J, Zhu, J, Shen, W, Fahr, B.J, Zhong, M, Taylor, L, Randal, M, McDowell, R.S, Hansen, S.K. | 登録日 | 2004-04-28 | 公開日 | 2004-07-20 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Allosteric inhibition of protein tyrosine phosphatase 1B. Nat.Struct.Mol.Biol., 11, 2004
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3LB9
| Crystal structure of the B. circulans cpA123 circular permutant | 分子名称: | Endo-1,4-beta-xylanase | 著者 | D'Angelo, I, Reitinger, S, Ludwiczek, M, Strynadka, N, Withers, S.G, Mcintosh, L.P. | 登録日 | 2010-01-08 | 公開日 | 2010-03-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Circular permutation of Bacillus circulans xylanase: a kinetic and structural study. Biochemistry, 49, 2010
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7ZEX
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6LY9
| The membrane-embedded Vo domain of V/A-ATPase from Thermus thermophilus | 分子名称: | V-type ATP synthase subunit C, V-type ATP synthase subunit E, V-type ATP synthase subunit I, ... | 著者 | Kishikawa, J, Nakanishi, A, Furuta, A, Kato, T, Namba, K, Tamakoshi, M, Mitsuoka, K, Yokoyama, K. | 登録日 | 2020-02-13 | 公開日 | 2020-09-09 | 最終更新日 | 2020-09-30 | 実験手法 | ELECTRON MICROSCOPY (3.93 Å) | 主引用文献 | Mechanical inhibition of isolated V o from V/A-ATPase for proton conductance. Elife, 9, 2020
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7SJN
| HtrA1:Fab15H6.v4 complex | 分子名称: | Fab15H6.v4 Heavy Chain, Fab15H6.v4 Light Chain, Serine protease HTRA1 | 著者 | Gerhardy, S, Green, E, Estevez, A, Arthur, C.P, Ultsch, M, Rohou, A, Kirchhofer, D. | 登録日 | 2021-10-18 | 公開日 | 2022-09-07 | 最終更新日 | 2022-09-21 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Allosteric inhibition of HTRA1 activity by a conformational lock mechanism to treat age-related macular degeneration. Nat Commun, 13, 2022
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116D
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117D
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6LLW
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7NI4
| Human ATM kinase domain with bound M4076 inhibitor | 分子名称: | 8-(1,3-dimethylpyrazol-4-yl)-1-(3-fluoranyl-5-methoxy-pyridin-4-yl)-7-methoxy-3-methyl-imidazo[4,5-c]quinolin-2-one, Serine-protein kinase ATM, ZINC ION | 著者 | Stakyte, K, Rotheneder, M. | 登録日 | 2021-02-11 | 公開日 | 2021-09-01 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Molecular basis of human ATM kinase inhibition. Nat.Struct.Mol.Biol., 28, 2021
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1WZ1
| Crystal structure of the Fv fragment complexed with dansyl-lysine | 分子名称: | Ig heavy chain, Ig light chain, N~6~-{[5-(DIMETHYLAMINO)-1-NAPHTHYL]SULFONYL}-L-LYSINE | 著者 | Nakasako, M, Oka, T, Mashumo, M, Takahashi, H, Shimada, I, Yamaguchi, Y, Kato, K, Arata, Y. | 登録日 | 2005-02-21 | 公開日 | 2006-01-31 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Conformational dynamics of complementarity-determining region H3 of an anti-dansyl Fv fragment in the presence of its hapten J.Mol.Biol., 351, 2005
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4KE8
| Crystal structure of Monoglyceride lipase from Bacillus sp. H257 in complex with monopalmitoyl glycerol analogue | 分子名称: | Thermostable monoacylglycerol lipase, tetradecyl hydrogen (R)-(3-azidopropyl)phosphonate | 著者 | Rengachari, S, Aschauer, P, Gruber, K, Dreveny, I, Oberer, M. | 登録日 | 2013-04-25 | 公開日 | 2013-09-18 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase. J.Biol.Chem., 288, 2013
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