6SEI
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![BU of 6sei by Molmil](/molmil-images/mine/6sei) | Recognition and processing of branched DNA substrates by Slx1-Slx4 nuclease | 分子名称: | CALCIUM ION, DNA (32-MER), Structure-specific endonuclease subunit SLX1, ... | 著者 | Gaur, V, Zajko, W, Nirwal, S, Szlachcic, A, Gapinska, M, Nowotny, M. | 登録日 | 2019-07-30 | 公開日 | 2019-09-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Recognition and processing of branched DNA substrates by Slx1-Slx4 nuclease. Nucleic Acids Res., 47, 2019
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6F2G
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![BU of 6f2g by Molmil](/molmil-images/mine/6f2g) | Bacterial asc transporter crystal structure in open to in conformation | 分子名称: | Nanobody 74, Putative amino acid/polyamine transport protein, ZINC ION | 著者 | Fort, J, Errasti-Murugarren, E, Carpena, X, Palacin, M, Fita, I. | 登録日 | 2017-11-24 | 公開日 | 2019-04-24 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | 主引用文献 | L amino acid transporter structure and molecular bases for the asymmetry of substrate interaction. Nat Commun, 10, 2019
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6SGF
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![BU of 6sgf by Molmil](/molmil-images/mine/6sgf) | Molecular insight into a new low affinity xylan binding module CBM86, from the xylanolytic gut symbiont Roseburia intestinalis. | 分子名称: | Beta-xylanase, CADMIUM ION, CHLORIDE ION, ... | 著者 | Ejby, M, Abou Hachem, M, Leth, M.L, Guskov, A, Slotboom, D. | 登録日 | 2019-08-04 | 公開日 | 2019-11-20 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.756 Å) | 主引用文献 | Molecular insight into a new low-affinity xylan binding module from the xylanolytic gut symbiont Roseburia intestinalis. Febs J., 287, 2020
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6F2W
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![BU of 6f2w by Molmil](/molmil-images/mine/6f2w) | Bacterial asc transporter crystal structure in open to in conformation | 分子名称: | ALPHA-AMINOISOBUTYRIC ACID, Nanobody 74, Putative amino acid/polyamine transport protein, ... | 著者 | Fort, J, Errasti-Murugarren, E, Carpena, X, Palacin, M, Fita, I. | 登録日 | 2017-11-27 | 公開日 | 2019-04-24 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | L amino acid transporter structure and molecular bases for the asymmetry of substrate interaction. Nat Commun, 10, 2019
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5BY9
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3O56
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![BU of 3o56 by Molmil](/molmil-images/mine/3o56) | Catalytic domain of human phosphodiesterase 4b2b in complex with a 5-heterocycle pyrazolopyridine inhibitor | 分子名称: | 1-ethyl-5-[3-(2-oxo-2-pyrrolidin-1-ylethyl)-1,2,4-oxadiazol-5-yl]-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-b]pyridin-4-amine, ARSENIC, GLYCEROL, ... | 著者 | Somers, D.O, Neu, M. | 登録日 | 2010-07-28 | 公開日 | 2011-08-03 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Pyrazolopyridines as potent PDE4B inhibitors: 5-heterocycle SAR. Bioorg.Med.Chem.Lett., 20, 2010
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6PBI
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![BU of 6pbi by Molmil](/molmil-images/mine/6pbi) | Crystal Structure of EcDsbA in a complex with purified morpholine 8 | 分子名称: | 2-methyl-4-{4-[2-(morpholin-4-yl)-2-oxoethyl]phenoxy}benzonitrile, COPPER (II) ION, Thiol:disulfide interchange protein DsbA | 著者 | Ilyichova, O.V, Bentley, M, Doak, B, Scanlon, M.J. | 登録日 | 2019-06-13 | 公開日 | 2020-05-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Rapid Elaboration of Fragments into Leads by X-ray Crystallographic Screening of Parallel Chemical Libraries (REFiL X ). J.Med.Chem., 63, 2020
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1XDF
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![BU of 1xdf by Molmil](/molmil-images/mine/1xdf) | Crystal structure of pathogenesis-related protein LlPR-10.2A from yellow lupine | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, PR10.2A, SODIUM ION | 著者 | Pasternak, O, Biesiadka, J, Dolot, R, Handschuh, L, Bujacz, G, Sikorski, M.M, Jaskolski, M. | 登録日 | 2004-09-06 | 公開日 | 2005-02-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of a yellow lupin pathogenesis-related PR-10 protein belonging to a novel subclass. Acta Crystallogr.,Sect.D, 61, 2005
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1SUX
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![BU of 1sux by Molmil](/molmil-images/mine/1sux) | CRYSTALLOGRAPHIC ANALYSIS OF THE COMPLEX BETWEEN TRIOSEPHOSPHATE ISOMERASE FROM TRYPANOSOMA CRUZI AND 3-(2-benzothiazolylthio)-1-propanesulfonic acid | 分子名称: | 3-(2-BENZOTHIAZOLYLTHIO)-1-PROPANESULFONIC ACID, SULFATE ION, Triosephosphate isomerase, ... | 著者 | Tellez-Valencia, A, Olivares-Illana, V, Hernandez-Santoyo, A, Perez-Montfort, R, Costas, M, Rodriguez-Romero, A, Tuena De Gomez-Puyou, M, Gomez-Puyou, A. | 登録日 | 2004-03-26 | 公開日 | 2004-08-24 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Inactivation of triosephosphate isomerase from Trypanosoma cruzi by an agent that perturbs its dimer interface. J.Mol.Biol., 341, 2004
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1BW0
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![BU of 1bw0 by Molmil](/molmil-images/mine/1bw0) | CRYSTAL STRUCTURE OF TYROSINE AMINOTRANSFERASE FROM TRYPANOSOMA CRUZI | 分子名称: | PROTEIN (TYROSINE AMINOTRANSFERASE) | 著者 | Blankenfeldt, W, Montemartini, M, Hunter, G.R, Kalisz, H.M, Nowicki, C, Hecht, H.J. | 登録日 | 1998-09-28 | 公開日 | 1999-09-27 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of Trypanosoma cruzi tyrosine aminotransferase: substrate specificity is influenced by cofactor binding mode. Protein Sci., 8, 1999
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1X9R
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![BU of 1x9r by Molmil](/molmil-images/mine/1x9r) | Umecyanin from Horse Raddish- Crystal Structure of the oxidised form | 分子名称: | COPPER (II) ION, Umecyanin | 著者 | Koch, M, Velarde, M, Harrison, M.D, Echt, S, Fischer, M, Messerschmidt, A, Dennison, C. | 登録日 | 2004-08-24 | 公開日 | 2005-03-22 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structures of Oxidized and Reduced Stellacyanin from Horseradish Roots J.Am.Chem.Soc., 127, 2005
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1JKA
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![BU of 1jka by Molmil](/molmil-images/mine/1jka) | HUMAN LYSOZYME MUTANT WITH GLU 35 REPLACED BY ASP | 分子名称: | LYSOZYME, NITRATE ION | 著者 | Muraki, M, Harata, K, Goda, S, Nagahora, H. | 登録日 | 1996-11-13 | 公開日 | 1997-05-15 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Importance of van der Waals contact between Glu 35 and Trp 109 to the catalytic action of human lysozyme. Protein Sci., 6, 1997
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6AWT
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![BU of 6awt by Molmil](/molmil-images/mine/6awt) | Structure of PR 10 Allergen in complex with epicatechin | 分子名称: | (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol, BENZOIC ACID, PR 10 protein, ... | 著者 | Offermann, L.R, Perdue, M, McBride, J, Hurlburt, B.K, Maleki, S.J, Pote, S.S, Chruszcz, M. | 登録日 | 2017-09-06 | 公開日 | 2018-09-12 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of PR-10 Allergen Ara h 8.01. To Be Published
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6ETZ
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![BU of 6etz by Molmil](/molmil-images/mine/6etz) | Cold-adapted beta-D-galactosidase from Arthrobacter sp. 32cB | 分子名称: | ACETATE ION, Beta-galactosidase, MALONATE ION, ... | 著者 | Rutkiewicz-Krotewicz, M, Bujacz, A, Bujacz, G. | 登録日 | 2017-10-27 | 公開日 | 2018-01-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | In Situ Random Microseeding and Streak Seeding Used for Growth of Crystals of Cold-Adapted Beta-D-Galactosidases: Crystal Structure of BetaDG from Arthrobacter sp. 32cB Crystals, 8, 2018
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6SED
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![BU of 6sed by Molmil](/molmil-images/mine/6sed) | Cold-adapted beta-D-galactosidase from Arthrobacter sp. 32cB in complex with galactose | 分子名称: | ACETATE ION, Beta-galactosidase, FORMIC ACID, ... | 著者 | Rutkiewicz, M, Bujacz, A, Kaminska, P, Bujacz, G. | 登録日 | 2019-07-29 | 公開日 | 2019-09-11 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.233 Å) | 主引用文献 | Active Site Architecture and Reaction Mechanism Determination of Cold Adapted beta-d-galactosidase fromArthrobactersp. 32cB. Int J Mol Sci, 20, 2019
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3NZJ
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![BU of 3nzj by Molmil](/molmil-images/mine/3nzj) | Crystal structure of yeast 20S proteasome in complex with ligand 2a | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Proteasome component C1, Proteasome component C11, ... | 著者 | Groll, M, Gallastegui, N, Marechal, X, Le Ravalec, V, Basse, N, Richy, N, Genin, E, Huber, R, Moroder, M, Vidal, V, Reboud-Ravaux, M. | 登録日 | 2010-07-16 | 公開日 | 2011-02-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | 20S proteasome inhibition: designing noncovalent linear peptide mimics of the natural product TMC-95A. Chemmedchem, 5, 2010
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5IJD
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![BU of 5ijd by Molmil](/molmil-images/mine/5ijd) | The crystal structure of mouse TLR4/MD-2/lipid A complex | 分子名称: | (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wang, Y, Su, L, Morin, M.D, Jones, B.T, Whitby, L.R, Surakattula, M, Huang, H, Shi, H, Choi, J.H, Wang, K, Moresco, E.M, Berger, M, Zhan, X, Zhang, H, Boger, D.L, Beutler, B. | 登録日 | 2016-03-01 | 公開日 | 2016-04-27 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS. Proc.Natl.Acad.Sci.USA, 113, 2016
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6FLG
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6SJJ
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![BU of 6sjj by Molmil](/molmil-images/mine/6sjj) | A new modulated crystal structure of ANS complex of St John's wort Hyp-1 protein with 36 protein molecules in the asymmetric unit of the supercell | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8-ANILINO-1-NAPHTHALENE SULFONATE, CITRATE ANION, ... | 著者 | Smietanska, J, Sliwiak, J, Gilski, M, Dauter, Z, Strzalka, R, Wolny, J, Jaskolski, M. | 登録日 | 2019-08-13 | 公開日 | 2020-06-24 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A new modulated crystal structure of the ANS complex of the St John's wort Hyp-1 protein with 36 protein molecules in the asymmetric unit of the supercell. Acta Crystallogr D Struct Biol, 76, 2020
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6SBQ
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![BU of 6sbq by Molmil](/molmil-images/mine/6sbq) | The crystal structure of PfA-M1 in complex with 7-amino-4-phenyl-5,7,8,9-tetrahydrobenzocyclohepten-6-one | 分子名称: | DI(HYDROXYETHYL)ETHER, M1-family alanyl aminopeptidase, MALONATE ION, ... | 著者 | Salomon, E, Schmitt, M, Mouray, E, McEwen, A.G, Torchy, M, Poussin-Courmontagne, P, Alavi, S, Tarnus, C, Cavarelli, J, Florent, I, Albrecht, S. | 登録日 | 2019-07-22 | 公開日 | 2020-03-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | 主引用文献 | Aminobenzosuberone derivatives as PfA-M1 inhibitors: Molecular recognition and antiplasmodial evaluation. Bioorg.Chem., 98, 2020
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7OFQ
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2MUE
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![BU of 2mue by Molmil](/molmil-images/mine/2mue) | Structure Immunogenicity and Protectivity Relationship for the 1585 Malarial Peptide and Its Substitution Analogues | 分子名称: | Merozoite surface protein 1 | 著者 | Espejo, F, Cubillos, M, Salazar, L, Guzman, F, Urquiza, M, Ocampo, M, Silva, Y, Rodriguez, R, Lioy, E, Patarroyo, M. | 登録日 | 2014-09-08 | 公開日 | 2014-10-08 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure, Immunogenicity, and Protectivity Relationship for the 1585 Malarial Peptide and Its Substitution Analogues. Angew.Chem.Int.Ed.Engl., 40, 2001
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8C86
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![BU of 8c86 by Molmil](/molmil-images/mine/8c86) | Crystal structure of human transthyretin in complex with 3-O-methyltolcapone analogue 2 | 分子名称: | (2,4-dimethylphenyl)-(3-methoxy-5-nitro-4-oxidanyl-phenyl)methanone, Transthyretin | 著者 | Poonsiri, T, Benini, S, Loconte, V, Cianci, M. | 登録日 | 2023-01-18 | 公開日 | 2024-01-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | 3-O-Methyltolcapone and Its Lipophilic Analogues Are Potent Inhibitors of Transthyretin Amyloidogenesis with High Permeability and Low Toxicity. Int J Mol Sci, 25, 2023
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8C85
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![BU of 8c85 by Molmil](/molmil-images/mine/8c85) | Crystal structure of human transthyretin in complex with 3-O-methyltolcapone analogue 1 | 分子名称: | (3,5-dimethylphenyl)-(3-methoxy-5-nitro-4-oxidanyl-phenyl)methanone, Transthyretin | 著者 | Poonsiri, T, Benini, S, Loconte, V, Cianci, M. | 登録日 | 2023-01-18 | 公開日 | 2024-01-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | 主引用文献 | 3-O-Methyltolcapone and Its Lipophilic Analogues Are Potent Inhibitors of Transthyretin Amyloidogenesis with High Permeability and Low Toxicity. Int J Mol Sci, 25, 2023
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7F1I
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![BU of 7f1i by Molmil](/molmil-images/mine/7f1i) | Designed enzyme RA61 M48K/I72D mutant: form II | 分子名称: | Engineered Retroaldolase | 著者 | Fujioka, T, Oka, M, Numoto, N, Ito, N, Oda, M, Tanaka, F. | 登録日 | 2021-06-09 | 公開日 | 2021-11-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Varying the Directionality of Protein Catalysts for Aldol and Retro-Aldol Reactions. Chembiochem, 23, 2022
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