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PDB: 51689 件

5VYK
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Crystal structure of the BRS domain of BRAF in complex with the CC-SAM domain of KSR1
分子名称: Chimera protein of BRS domain of BRAF and CC-SAM domain of KSR1,Serine/threonine-protein kinase B-raf, GLYCEROL
著者Maisonneuve, P, Kurinov, I, Marullo, S.A, Lavoie, H, Thevakumaran, N, Sahmi, M, Jin, T, Therrien, M, SIcheri, F.
登録日2017-05-25
公開日2018-02-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.749 Å)
主引用文献MEK drives BRAF activation through allosteric control of KSR proteins.
Nature, 554, 2018
1J1F
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Crystal structure of the RNase MC1 mutant N71T in complex with 5'-GMP
分子名称: GUANOSINE-5'-MONOPHOSPHATE, RIBONUCLEASE MC1
著者Numata, T, Suzuki, A, Kakuta, Y, Kimura, K, Yao, M, Tanaka, I, Yoshida, Y, Ueda, T, Kimura, M.
登録日2002-12-03
公開日2003-05-20
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structures of the Ribonuclease MC1 Mutants N71T and N71S in Complex with 5'-GMP: Structural Basis for Alterations in Substrate Specificity
Biochemistry, 42, 2003
1J2M
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Solution structure of CPI-17(22-120)
分子名称: 17-kDa PKC-potentiated inhibitory protein of PP1
著者Ohki, S, Eto, M, Takada, R, Shimizu, M, Brautigan, D.L, Kainosho, M.
登録日2003-01-07
公開日2003-06-17
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Distinctive Solution Conformation of Phosphatase Inhibitor CPI-17 Substituted with Aspartate at the Phosphorylation-site Threonine Residue
J.Mol.Biol., 326, 2003
2PZ9
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BU of 2pz9 by Molmil
Crystal structure of putative transcriptional regulator SCO4942 from Streptomyces coelicolor
分子名称: Putative regulatory protein, SULFATE ION
著者Filippova, E.V, Chruszcz, M, Xu, X, Zheng, H, Cymborowski, M, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2007-05-17
公開日2007-06-19
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献In situ proteolysis for protein crystallization and structure determination.
Nat.Methods, 4, 2007
6KHX
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BU of 6khx by Molmil
Crystal structure of Prx from Akkermansia muciniphila
分子名称: CALCIUM ION, Peroxiredoxin
著者Li, M, Wang, J, Xu, W, Wang, Y, Zhang, M, Wang, M.
登録日2019-07-16
公開日2020-02-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Crystal structure of Akkermansia muciniphila peroxiredoxin reveals a novel regulatory mechanism of typical 2-Cys Prxs by a distinct loop.
Febs Lett., 594, 2020
1MD7
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BU of 1md7 by Molmil
Monomeric structure of the zymogen of complement protease C1r
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C1R COMPLEMENT SERINE PROTEASE
著者Budayova-Spano, M, Grabarse, W, Thielens, N.M, Hillen, H, Lacroix, M, Schmidt, M, Fontecilla-Camps, J, Arlaud, G.J, Gaboriaud, C.
登録日2002-08-07
公開日2003-08-07
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Monomeric structures of the zymogen and active catalytic domain of complement protease c1r: further insights into the c1 activation mechanism
Structure, 10, 2002
5VSV
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BU of 5vsv by Molmil
Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P225
分子名称: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase, {2-chloro-5-[({2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}carbamoyl)amino]phenoxy}acetic acid
著者Maltseva, N, Kim, Y, Mulligan, R, Makowska-Grzyska, M, Gu, M, Gollapalli, D.R, Hedstrom, L, Joachimiak, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2017-05-12
公開日2017-05-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.205 Å)
主引用文献Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P225
To Be Published
3OS6
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BU of 3os6 by Molmil
Crystal structure of putative 2,3-dihydroxybenzoate-specific isochorismate synthase, DhbC from Bacillus anthracis.
分子名称: GLYCEROL, Isochorismate synthase DhbC, POLYETHYLENE GLYCOL (N=34), ...
著者Domagalski, M.J, Chruszcz, M, Skarina, T, Onopriyenko, O, Cymborowski, M, Savchenko, A, Edwards, A, Anderson, W, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2010-09-08
公開日2010-10-20
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of isochorismate synthase DhbC from Bacillus anthracis.
Acta Crystallogr.,Sect.F, 69, 2013
2ORO
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BU of 2oro by Molmil
Murine inducible nitric oxide synthase oxygenase domain (delta 114) (r)-1-(2-imidazol-1-yl-6-methyl-pyrimidin-4-yl)-pyrrolidine-2-carboxylic acid (2-benzo[1,3]dioxol-5-yl-ethyl)-amide complex
分子名称: N-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-1-[2-(1H-IMIDAZOL-1-YL)-6-METHYLPYRIMIDIN-4-YL]-D-PROLINAMIDE, PROTOPORPHYRIN IX CONTAINING FE, SULFITE ION, ...
著者Adler, M, Whitlow, M.
登録日2007-02-04
公開日2007-04-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Design, Synthesis, and Activity of 2-Imidazol-1-ylpyrimidine Derived Inducible Nitric Oxide Synthase Dimerization Inhibitors
J.Med.Chem., 50, 2007
3OND
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BU of 3ond by Molmil
Crystal structure of Lupinus luteus S-adenosyl-L-homocysteine hydrolase in complex with adenosine
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE, Adenosylhomocysteinase, ...
著者Brzezinski, K, Jaskolski, M.
登録日2010-08-28
公開日2011-08-31
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.17 Å)
主引用文献High-resolution structures of complexes of plant S-adenosyl-L-homocysteine hydrolase (Lupinus luteus).
Acta Crystallogr.,Sect.D, 68, 2012
4NEC
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BU of 4nec by Molmil
Conversion of a Disulfide Bond into a Thioacetal Group during Echinomycin Biosynthesis
分子名称: 2-CARBOXYQUINOXALINE, ACETATE ION, Echinomycin, ...
著者Hotta, K, Keegan, R.M, Ranganathan, S, Fang, M, Bibby, J, Winn, M.D, Sato, M, Lian, M, Watanabe, K, Rigden, D.J, Kim, C.-Y.
登録日2013-10-29
公開日2014-01-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Conversion of a disulfide bond into a thioacetal group during echinomycin biosynthesis.
Angew.Chem.Int.Ed.Engl., 53, 2014
5DCQ
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BU of 5dcq by Molmil
Crystal structure of bacterial adhesin, FNE from Streptococcus equi spp. equi.
分子名称: FORMIC ACID, Fibronectin-binding protein, artificial repeat proteins (alphaREP3)
著者Tiouajni, M, Graille, M, van Tilbeurgh, H.
登録日2015-08-24
公開日2016-06-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structural and functional analysis of the fibronectin-binding protein FNE from Streptococcus equi spp. equi.
FEBS J., 281, 2014
1Z81
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BU of 1z81 by Molmil
Crystal Structure of cyclophilin from Plasmodium yoelii.
分子名称: cyclophilin
著者Mulichak, A, Alam, Z, Amani, M, Lew, J, Wasney, G, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Hui, R, Vedadi, M, Structural Genomics Consortium (SGC)
登録日2005-03-29
公開日2005-04-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
4NPX
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BU of 4npx by Molmil
Structure of hypothetical protein Cj0539 from Campylobacter jejuni
分子名称: Putative uncharacterized protein
著者Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Adkins, J.N, Endres, M, Nissen, M, Konkel, M, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG), Program for the Characterization of Secreted Effector Proteins (PCSEP)
登録日2013-11-22
公開日2014-01-01
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structure of hypothetical protein Cj0539 from Campylobacter jejuni
To be Published
3P4J
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BU of 3p4j by Molmil
Ultra-high resolution structure of d(CGCGCG)2 Z-DNA
分子名称: DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), SPERMINE
著者Brzezinski, K, Brzuszkiewicz, A, Dauter, M, Kubicki, M, Jaskolski, M, Dauter, Z.
登録日2010-10-06
公開日2011-08-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (0.55 Å)
主引用文献High regularity of Z-DNA revealed by ultra high-resolution crystal structure at 0.55 A.
Nucleic Acids Res., 39, 2011
2AAS
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BU of 2aas by Molmil
HIGH-RESOLUTION THREE-DIMENSIONAL STRUCTURE OF RIBONUCLEASE A IN SOLUTION BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
分子名称: RIBONUCLEASE A
著者Santoro, J, Gonzalez, C, Bruix, M, Neira, J.L, Nieto, J.L, Herranz, J, Rico, M.
登録日1992-11-20
公開日1994-01-31
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献High-resolution three-dimensional structure of ribonuclease A in solution by nuclear magnetic resonance spectroscopy.
J.Mol.Biol., 229, 1993
1MQ5
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Crystal Structure of 3-chloro-N-[4-chloro-2-[[(4-chlorophenyl)amino]carbonyl]phenyl]-4-[(4-methyl-1-piperazinyl)methyl]-2-thiophenecarboxamide Complexed with Human Factor Xa
分子名称: 3-CHLORO-N-[4-CHLORO-2-[[(4-CHLOROPHENYL)AMINO]CARBONYL]PHENYL]-4-[(4-METHYL-1-PIPERAZINYL)METHYL]-2-THIOPHENECARBOXAMIDE, CALCIUM ION, COAGULATION FACTOR X HEAVY CHAIN, ...
著者Adler, M, Whitlow, M.
登録日2002-09-13
公開日2003-01-28
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures of Two Potent Nonamidine Inhibitors Bound to Factor Xa
Biochemistry, 41, 2002
1Z5M
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Crystal Structure Of N1-[3-[[5-bromo-2-[[3-[(1-pyrrolidinylcarbonyl)amino]phenyl]amino]-4-pyrimidinyl]amino]propyl]-2,2-dimethylpropanediamide Complexed with Human PDK1
分子名称: 3-phosphoinositide dependent protein kinase-1, CHLORIDE ION, GLYCEROL, ...
著者Whitlow, M, Adler, M.
登録日2005-03-18
公開日2005-04-19
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Novel small molecule inhibitors of 3-phosphoinositide-dependent kinase-1.
J.Biol.Chem., 280, 2005
1Z7D
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BU of 1z7d by Molmil
Ornithine aminotransferase PY00104 from Plasmodium Yoelii
分子名称: ornithine aminotransferase
著者Walker, J.R, Alam, Z, Amani, M, Lew, J, Wasney, G, Boulanger, K, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Hui, R, Vedadi, M, Structural Genomics Consortium (SGC)
登録日2005-03-24
公開日2005-07-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
2A22
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BU of 2a22 by Molmil
Structure of Vacuolar Protein Sorting 29 from Cryptosporidium Parvum
分子名称: vacuolar protein sorting 29
著者Brokx, S, Zhao, Y, Alam, Z, Lew, J, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Hui, R, Walker, J.R, Structural Genomics Consortium (SGC)
登録日2005-06-21
公開日2005-08-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.198 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
1TGS
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BU of 1tgs by Molmil
THREE-DIMENSIONAL STRUCTURE OF THE COMPLEX BETWEEN PANCREATIC SECRETORY INHIBITOR (KAZAL TYPE) AND TRYPSINOGEN AT 1.8 ANGSTROMS RESOLUTION. STRUCTURE SOLUTION, CRYSTALLOGRAPHIC REFINEMENT AND PRELIMINARY STRUCTURAL INTERPRETATION
分子名称: CALCIUM ION, PANCREATIC SECRETORY TRYPSIN INHIBITOR (KAZAL TYPE), SULFATE ION, ...
著者Bolognesi, M, Gatti, G, Menegatti, E, Guarneri, M, Marquart, M, Papamokos, E, Huber, R.
登録日1982-09-27
公開日1983-01-18
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Three-dimensional structure of the complex between pancreatic secretory trypsin inhibitor (Kazal type) and trypsinogen at 1.8 A resolution. Structure solution, crystallographic refinement and preliminary structural interpretation.
J.Mol.Biol., 162, 1982
1TU5
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Crystal structure of bovine plasma copper-containing amine oxidase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Lunelli, M, Di Paolo, M.L, Biadene, M, Calderone, V, Scarpa, M, Battistutta, R, Rigo, A, Zanotti, G.
登録日2004-06-24
公開日2005-02-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Crystal structure of amine oxidase from bovine serum.
J.Mol.Biol., 346, 2005
2A4A
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BU of 2a4a by Molmil
Deoxyribose-phosphate aldolase from P. yoelii
分子名称: deoxyribose-phosphate aldolase
著者Walker, J.R, Amani, M, Lew, J, Wiegelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Hui, R, Vedadi, M, Structural Genomics Consortium (SGC)
登録日2005-06-28
公開日2005-09-06
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
1MOH
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BU of 1moh by Molmil
FERRIC MONOMERIC HEMOGLOBIN I (HB I)
分子名称: HYDROSULFURIC ACID, MONOMERIC HEMOGLOBIN I, PROTOPORPHYRIN IX CONTAINING FE
著者Rizzi, M, Wittenberg, J.B, Ascenzi, P, Bolognesi, M.
登録日1996-02-27
公開日1996-08-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural bases for sulfide recognition in Lucina pectinata hemoglobin I.
J.Mol.Biol., 258, 1996
1MD8
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BU of 1md8 by Molmil
Monomeric structure of the active catalytic domain of complement protease C1r
分子名称: C1R COMPLEMENT SERINE PROTEASE
著者Budayova-Spano, M, Grabarse, W, Thielens, N.M, Hillen, H, Lacroix, M, Schmidt, M, Fontecilla-Camps, J, Arlaud, G.J, Gaboriaud, C.
登録日2002-08-07
公開日2003-08-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Monomeric structures of the zymogen and active catalytic domain of complement protease c1r: further insights into the c1 activation mechanism
Structure, 10, 2002

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