2QG8
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![BU of 2qg8 by Molmil](/molmil-images/mine/2qg8) | Plasmodium yoelii acyl carrier protein synthase PY06285 with ADP bound | 分子名称: | ADENOSINE-3'-5'-DIPHOSPHATE, Acyl Carrier Protein Synthase PY06285, MAGNESIUM ION | 著者 | Lunin, V.V, Wernimont, A.K, Lew, J, Wasney, G, Kozieradzki, I, Vedadi, M, Bochkarev, A, Arrowsmith, C.H, Sundstrom, M, Weigelt, J, Edwards, A.E, Hui, R, Brokx, S, Altamentova, S, Structural Genomics Consortium (SGC) | 登録日 | 2007-06-28 | 公開日 | 2007-07-24 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Plasmodium yoelii acyl carrier protein synthase PY06285 with ADP bound TO BE PUBLISHED
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6F17
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![BU of 6f17 by Molmil](/molmil-images/mine/6f17) | Structure of Mb NMH H64V, V68A mutant resting state | 分子名称: | Myoglobin, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Tinzl, M, Hayashi, T, Mori, T, Hilvert, D. | 登録日 | 2017-11-21 | 公開日 | 2018-08-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Capture and characterization of a reactive haem-carbenoid complex in an artificial metalloenzyme Nat Catal, 1, 2018
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6F19
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![BU of 6f19 by Molmil](/molmil-images/mine/6f19) | Structure of Mb NMH H64V, V68A mutant complex with EDA incubated at room temperature for 5 min | 分子名称: | ETHYL ACETATE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Tinzl, M, Hayashi, T, Mori, T, Hilvert, D. | 登録日 | 2017-11-21 | 公開日 | 2018-08-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.895 Å) | 主引用文献 | Capture and characterization of a reactive haem-carbenoid complex in an artificial metalloenzyme Nat Catal, 1, 2018
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5EUV
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![BU of 5euv by Molmil](/molmil-images/mine/5euv) | Crystal structure of a cold-adapted dimeric beta-D-galactosidase from Paracoccus sp. 32d strain | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, Beta-D-galactosidase, ... | 著者 | Rutkiewicz-Krotewicz, M, Bujacz, A, Pietrzyk, A.J, Sekula, B, Bujacz, G. | 登録日 | 2015-11-19 | 公開日 | 2016-09-14 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural studies of a cold-adapted dimeric beta-D-galactosidase from Paracoccus sp. 32d. Acta Crystallogr D Struct Biol, 72, 2016
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6SE9
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![BU of 6se9 by Molmil](/molmil-images/mine/6se9) | Cold-adapted beta-D-galactosidase from Arthrobacter sp. 32cB mutant E441Q in complex with lactose bound in shallow mode | 分子名称: | ACETATE ION, Beta-galactosidase, FORMIC ACID, ... | 著者 | Rutkiewicz, M, Bujacz, A, Bujacz, G. | 登録日 | 2019-07-29 | 公開日 | 2019-09-11 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.965 Å) | 主引用文献 | Active Site Architecture and Reaction Mechanism Determination of Cold Adapted beta-d-galactosidase fromArthrobactersp. 32cB. Int J Mol Sci, 20, 2019
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6ETI
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![BU of 6eti by Molmil](/molmil-images/mine/6eti) | Structure of inhibitor-bound ABCG2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, 5D3(Fab) light chain variable domain, ... | 著者 | Jackson, S.M, Manolaridis, I, Kowal, J, Zechner, M, Altmann, K.H, Locher, K.P. | 登録日 | 2017-10-26 | 公開日 | 2018-04-11 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of small-molecule inhibition of human multidrug transporter ABCG2. Nat. Struct. Mol. Biol., 25, 2018
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2A58
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![BU of 2a58 by Molmil](/molmil-images/mine/2a58) | Structure of 6,7-Dimethyl-8-ribityllumazine synthase from Schizosaccharomyces pombe mutant W27Y with bound riboflavin | 分子名称: | 6,7-dimethyl-8-ribityllumazine synthase, PHOSPHATE ION, RIBOFLAVIN | 著者 | Koch, M, Breithaupt, C, Gerhardt, S, Haase, I, Weber, S, Cushman, M, Huber, R, Bacher, A, Fischer, M. | 登録日 | 2005-06-30 | 公開日 | 2005-07-19 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis of charge transfer complex formation by riboflavin bound to 6,7-dimethyl-8-ribityllumazine synthase Eur.J.Biochem., 271, 2004
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6F67
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![BU of 6f67 by Molmil](/molmil-images/mine/6f67) | Crystal structure of glutathione transferase Omega 3S from Trametes versicolor in complex with 3,4-Dihydroxybenzophenone | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, [3,4-bis(oxidanyl)phenyl]-phenyl-methanone, ... | 著者 | Schwartz, M, Favier, F, Didierjean, C. | 登録日 | 2017-12-05 | 公開日 | 2018-06-06 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.398 Å) | 主引用文献 | Molecular recognition of wood polyphenols by phase II detoxification enzymes of the white rot Trametes versicolor. Sci Rep, 8, 2018
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2QNW
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![BU of 2qnw by Molmil](/molmil-images/mine/2qnw) | Toxoplasma gondii apicoplast-targeted acyl carrier protein | 分子名称: | Acyl carrier protein, SODIUM ION, SULFATE ION, ... | 著者 | Lunin, V.V, Wernimont, A, Lew, J, Qiu, W, Lin, L, Hassanali, A, Kozieradzki, I, Zhao, Y, Schapira, M, Bochkarev, A, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A, Hui, R, Brokx, S, Structural Genomics Consortium (SGC) | 登録日 | 2007-07-19 | 公開日 | 2007-07-31 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Toxoplasma gondii apicoplast-targeted acyl carrier protein. To be Published
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3KZZ
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5MQ5
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![BU of 5mq5 by Molmil](/molmil-images/mine/5mq5) | A protease-resistant N24S Escherichia coli Asparaginase mutant with outstanding stability and enhanced anti-leukaemic activity | 分子名称: | ASPARTIC ACID, L-asparaginase 2 | 著者 | Maggi, M, Mittelman, S.D, Parmentier, J.H, Whitmire, J.M, Merrell, D.S, Scotti, C. | 登録日 | 2016-12-20 | 公開日 | 2017-11-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A protease-resistant Escherichia coli asparaginase with outstanding stability and enhanced anti-leukaemic activity in vitro. Sci Rep, 7, 2017
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6Y5V
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![BU of 6y5v by Molmil](/molmil-images/mine/6y5v) | Structure of Human Potassium Chloride Transporter KCC3b (S45D/T940D/T997D) in KCl | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 12 member 6, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Chi, G, Man, H, Ebenhoch, R, Reggiano, G, Pike, A.C.W, Wang, D, McKinley, G, Mukhopadhyay, S.M.M, MacLean, E.M, Chalk, R, Moreau, C, Snee, M, Bohstedt, T, Singh, N.K, Abrusci, P, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Marsden, B.D, Burgess-Brown, N.A, DiMaio, F, Duerr, K.L. | 登録日 | 2020-02-25 | 公開日 | 2020-07-15 | 最終更新日 | 2021-07-28 | 実験手法 | ELECTRON MICROSCOPY (4.08 Å) | 主引用文献 | Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters. Embo J., 40, 2021
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2QQE
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![BU of 2qqe by Molmil](/molmil-images/mine/2qqe) | Thymidine Kinase from Thermotoga Maritima in complex with Thymidine | 分子名称: | THYMIDINE, Thymidine kinase, ZINC ION | 著者 | Segura-Pena, D, Lichter, J, Trani, M, Konrad, M, Lavie, A, Lutz, S. | 登録日 | 2007-07-26 | 公開日 | 2007-10-16 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Quaternary structure change as a mechanism for the regulation of thymidine kinase 1-like enzymes. Structure, 15, 2007
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2A59
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![BU of 2a59 by Molmil](/molmil-images/mine/2a59) | Structure of 6,7-Dimethyl-8-ribityllumazine synthase from Schizosaccharomyces pombe mutant W27Y with bound ligand 5-nitroso-6-ribitylamino-2,4(1H,3H)-pyrimidinedione | 分子名称: | 5-NITROSO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE, 6,7-dimethyl-8-ribityllumazine synthase, PHOSPHATE ION | 著者 | Koch, M, Breithaupt, C, Gerhardt, S, Haase, I, Weber, S, Cushman, M, Huber, R, Bacher, A, Fischer, M. | 登録日 | 2005-06-30 | 公開日 | 2005-07-19 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis of charge transfer complex formation by riboflavin bound to 6,7-dimethyl-8-ribityllumazine synthase Eur.J.Biochem., 271, 2004
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6FE6
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![BU of 6fe6 by Molmil](/molmil-images/mine/6fe6) | Solution structure of a last generation P2-P4 macrocyclic inhibitor | 分子名称: | (3aR,7S,10S,12R,24aR)-7-cyclopentyl-N-{(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethenylcyclopropyl}-5,8-dioxo-1,2,3,3a,5,6,7,8,11,12,20,21,22,23,24,24a-hexadecahydro-10H-9,12-methanocyclopenta[18,19][1,10,3,6]dioxadiazacyclononadecino[12,11-b]quinoline-10-carboxamide, Non-structural 3 protease, ZINC ION | 著者 | Gallo, M, Eliseo, T, Cicero, D.O. | 登録日 | 2017-12-29 | 公開日 | 2019-01-30 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of a last generation macrocyclic inhibitor. Hepatitis C virus NS3 protease complex: when S prime region occupancy is not enough to stabilize the protein conformation in the absence of NS4A. To Be Published
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8FOX
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![BU of 8fox by Molmil](/molmil-images/mine/8fox) | AbeH (Tryptophan-5-halogenase) | 分子名称: | SULFATE ION, Tryptophan 5-halogenase | 著者 | Ashaduzzaman, M, Bellizzi, J.J. | 登録日 | 2023-01-03 | 公開日 | 2023-08-30 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Crystallographic and thermodynamic evidence of negative cooperativity of flavin and tryptophan binding in the flavin-dependent halogenases AbeH and BorH. Biorxiv, 2023
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1GX3
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![BU of 1gx3 by Molmil](/molmil-images/mine/1gx3) | M. smegmatis arylamine N-acetyl transferase | 分子名称: | ARYLAMINE N-ACETYLTRANSFERASE | 著者 | Sandy, J, Mushtaq, A, Kawamura, A, Sinclair, J, Sim, E, Noble, M. | 登録日 | 2002-03-26 | 公開日 | 2002-06-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Structure of Arylamine N-Acetyltransferase from Mycobacterium Smegmatis-an Enzyme which Inactivates the Anti-Tubercular Drug, Isoniazid J.Mol.Biol., 318, 2002
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6SEH
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![BU of 6seh by Molmil](/molmil-images/mine/6seh) | Recognition and processing of branched DNA substrates by Slx1-Slx4 nuclease | 分子名称: | Structure-specific endonuclease subunit SLX1, Structure-specific endonuclease subunit SLX4, ZINC ION | 著者 | Gaur, V, Zajko, W, Nirwal, S, Szlachcic, A, Gapinska, M, Nowotny, M. | 登録日 | 2019-07-30 | 公開日 | 2019-09-25 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Recognition and processing of branched DNA substrates by Slx1-Slx4 nuclease. Nucleic Acids Res., 47, 2019
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2A98
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![BU of 2a98 by Molmil](/molmil-images/mine/2a98) | Crystal structure of the catalytic domain of human inositol 1,4,5-trisphosphate 3-kinase C | 分子名称: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate 3-kinase C | 著者 | Hallberg, B.M, Ogg, D, Ehn, M, Graslund, S, Hammarstrom, M, Kotenyova, T, Nilsson-Ehle, P, Nordlund, P, Persson, C, Sagemark, J, Schuler, H, Stenmark, P, Thorsell, A.-G, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Structural Genomics Consortium (SGC) | 登録日 | 2005-07-11 | 公開日 | 2005-07-19 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The crystal structure of the catalytic domain of human inositol 1,4,5-trisphosphate 3-kinase C To be Published
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2R3A
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![BU of 2r3a by Molmil](/molmil-images/mine/2r3a) | Methyltransferase domain of human suppressor of variegation 3-9 homolog 2 | 分子名称: | Histone-lysine N-methyltransferase SUV39H2, S-ADENOSYLMETHIONINE, SERINE, ... | 著者 | Lunin, V.V, Wu, H, Zeng, H, Ren, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2007-08-29 | 公開日 | 2007-09-11 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural biology of human H3K9 methyltransferases Plos One, 5, 2010
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6F68
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![BU of 6f68 by Molmil](/molmil-images/mine/6f68) | Crystal structure glutathione transferase Omega 3S from Trametes versicolor in complex with 2,4,4'-trihydroxybenzophenone | 分子名称: | (2,4-dihydroxyphenyl)(4-hydroxyphenyl)methanone, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Schwartz, M, Favier, F, Didierjean, C. | 登録日 | 2017-12-05 | 公開日 | 2018-06-06 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.696 Å) | 主引用文献 | Molecular recognition of wood polyphenols by phase II detoxification enzymes of the white rot Trametes versicolor. Sci Rep, 8, 2018
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8FOV
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7AAW
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![BU of 7aaw by Molmil](/molmil-images/mine/7aaw) | Thioredoxin Reductase from Bacillus cereus | 分子名称: | ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Shoor, M, Gudim, I, Hersleth, H.-P, Hammerstad, M. | 登録日 | 2020-09-04 | 公開日 | 2021-09-15 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Thioredoxin reductase from Bacillus cereus exhibits distinct reduction and NADPH-binding properties. Febs Open Bio, 11, 2021
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8FLJ
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![BU of 8flj by Molmil](/molmil-images/mine/8flj) | Cas1-Cas2/3 integrase and IHF bound to CRISPR leader, repeat and foreign DNA | 分子名称: | CRISPR leader and repeat, anti-sense strand of DNA, CRISPR leader, ... | 著者 | Santiago-Frangos, A, Henriques, W.S, Wiegand, T, Gauvin, C, Buyukyoruk, M, Neselu, K, Eng, E.T, Lander, G.C, Wiedenheft, B. | 登録日 | 2022-12-21 | 公開日 | 2023-09-06 | 最終更新日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | 主引用文献 | Structure reveals why genome folding is necessary for site-specific integration of foreign DNA into CRISPR arrays. Nat.Struct.Mol.Biol., 30, 2023
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5F34
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![BU of 5f34 by Molmil](/molmil-images/mine/5f34) | Crystal structure of membrane associated PatA from Mycobacterium smegmatis in complex with S-hexadecyl Coenzyme A - P21 space group | 分子名称: | Phosphatidylinositol mannoside acyltransferase, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3~{S})-4-[[3-(2-hexadecylsulfanylethylamino)-3-oxidanylidene-propyl]amino]-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-butyl] hydrogen phosphate | 著者 | Albesa-Jove, D, Svetlikova, Z, Carreras-Gonzalez, A, Tersa, M, Sancho-Vaello, E, Cifuente, J.O, Mikusova, K, Guerin, M.E. | 登録日 | 2015-12-02 | 公開日 | 2016-03-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.281 Å) | 主引用文献 | Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA. Nat Commun, 7, 2016
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