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PDB: 51938 件

4RNM
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Crystal structure of human polymerase eta inserting dAMPnPP opposite DNA template containing an abasic site
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA Primar: AGCGTCAT, DNA Template: CAT(3DR)ATGACGCT, ...
著者Patra, A, Egli, M.
登録日2014-10-24
公開日2015-02-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.144 Å)
主引用文献Structural and Kinetic Analysis of Nucleoside Triphosphate Incorporation Opposite an Abasic Site by Human Translesion DNA Polymerase eta.
J.Biol.Chem., 290, 2015
8THL
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Cryo-EM structure of epinephrine-bound alpha-1A-adrenergic receptor in complex with heterotrimeric Gq-protein
分子名称: Endolysin,Alpha-1A adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Su, M, Huang, X.Y.
登録日2023-07-17
公開日2023-08-16
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of agonist specificity of alpha 1A -adrenergic receptor.
Nat Commun, 14, 2023
8HR4
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[D-Cys5,D-Lys16]-STp(5-17)
分子名称: DCY-CYS-GLU-LEU-CYS-CYS-ASN-PRO-ALA-CYS-ALA-DLY-CYS
著者Shimamoto, S, Hidaka, Y, Yoshino, S, Goto, M.
登録日2022-12-14
公開日2023-12-20
実験手法SOLUTION NMR
主引用文献The molecular basis of heat-stable enterotoxin for vaccine development and cancer cell detection
To Be Published
6LLQ
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Solution NMR structure of de novo Rossmann2x2 fold with most of the core mutated to valine, R2x2_VAL88
分子名称: VAL88
著者Kobayashi, N, Sugiki, T, Fujiwara, T, Koga, R, Yamamoto, M, Kosugi, T, Koga, N.
登録日2019-12-23
公開日2020-12-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Robust folding of a de novo designed ideal protein even with most of the core mutated to valine.
Proc.Natl.Acad.Sci.USA, 117, 2020
8THK
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Cryo-EM structure of A61603-bound alpha-1A-adrenergic receptor in complex with heterotrimeric Gq-protein
分子名称: Endolysin,Alpha-1A adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Su, M, Huang, X.Y.
登録日2023-07-17
公開日2023-08-16
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis of agonist specificity of alpha 1A -adrenergic receptor.
Nat Commun, 14, 2023
6LXG
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NMR solution structure of regulatory ACT domain of the Mycobacterium tuberculosis Rel protein
分子名称: GTP pyrophosphokinase
著者Shin, J, Singal, B, Manimekalai, M.S.S, Gruber, G.
登録日2020-02-11
公開日2020-11-04
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Atomic structure of, and valine binding to the regulatory ACT domain of the Mycobacterium tuberculosis Rel protein.
Febs J., 288, 2021
8TTP
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Crystal structure of class C beta-lactamase from Escherichia coli in complex with avibactam
分子名称: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 1,2-ETHANEDIOL, Beta-lactamase, ...
著者Chang, C, Maltseva, N, Endres, M, Joachimiak, A, Center for Structural Biology of Infectious Diseases (CSBID)
登録日2023-08-14
公開日2023-09-06
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Crystal structure of class C beta-lactamase from Escherichia coli in complex with avibactam
to be published
4RRU
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Myc3 N-terminal JAZ-binding domain[5-242] from arabidopsis
分子名称: CALCIUM ION, Transcription factor MYC3
著者Ke, J, Zhang, F, Zhou, X.E, Brunzelle, J.S, Zhou, M, Xu, H.E, Melcher, K, He, S.Y.
登録日2014-11-06
公開日2015-08-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
8HPP
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Crystal structure of human INTS3 with SAGE1
分子名称: Integrator complex subunit 3, Sarcoma antigen 1
著者Deng, W, Wu, J, Lei, M.
登録日2022-12-12
公開日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Cancer-testis antigen SAGE1 is a pan-cancer master regulator of RNA polymerase II
To Be Published
4RS9
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Structure of Myc3 N-terminal JAZ-binding domain [44-238] in complex with Jas motif of JAZ9
分子名称: Protein TIFY 7, Transcription factor MYC3
著者Ke, J, Zhang, F, Zhou, X.E, Brunzelle, J.S, Zhou, M, Xu, H.E, Melcher, K, He, S.Y.
登録日2014-11-07
公開日2015-08-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
4RSL
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Structure of fructosyl peptide oxidase from E. terrenum
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Fructosyl peptide oxidase, PHOSPHATE ION
著者Gan, W, Gao, F, Xing, K, Jia, M, Liu, H, Gong, W.
登録日2014-11-08
公開日2015-05-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of the substrate specificity of the FPOD/FAOD family revealed by fructosyl peptide oxidase from Eupenicillium terrenum
Acta Crystallogr.,Sect.F, 71, 2015
6M19
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Template lasso peptide C24 mutant W14F
分子名称: lasso peptide
著者Liu, X.H, Liu, T, Ma, X.J, Yu, J.H, Yang, D.H, Ma, M.
登録日2020-02-25
公開日2021-03-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Rational generation of lasso peptides based on biosynthetic gene mutations and site-selective chemical modifications.
Chem Sci, 12, 2021
8HNQ
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The structure of a alcohol dehydrogenase AKR13B2 with NADP
分子名称: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Chen, M, Yang, H, Lu, F.
登録日2022-12-08
公開日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structure of AKR13B2
To Be Published
1B8L
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Calcium-bound D51A/E101D/F102W Triple Mutant of Beta Carp Parvalbumin
分子名称: CALCIUM ION, CARBONATE ION, PROTEIN (PARVALBUMIN)
著者Cates, M.S, Berry, M.B, Ho, E, Li, Q, Potter, J.D, Phillips Jr, G.N.
登録日1999-02-01
公開日1999-10-05
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Metal-ion affinity and specificity in EF-hand proteins: coordination geometry and domain plasticity in parvalbumin.
Structure Fold.Des., 7, 1999
1B4T
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H48C YEAST CU(II)/ZN SUPEROXIDE DISMUTASE ROOM TEMPERATURE (298K) STRUCTURE
分子名称: CHLORIDE ION, COPPER (II) ION, PROTEIN (CU/ZN SUPEROXIDE DISMUTASE), ...
著者Hart, P.J, Balbirnie, M.M, Ogihara, N.L, Nersissian, A.M, Weiss, M.S, Valentine, J.S, Eisenberg, D.
登録日1998-12-23
公開日1999-12-23
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A structure-based mechanism for copper-zinc superoxide dismutase.
Biochemistry, 38, 1999
4XPN
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Crystal Structure of Protein Phosphate 1 complexed with PP1 binding domain of GADD34
分子名称: GLYCEROL, MANGANESE (II) ION, PHOSPHATE ION, ...
著者Choy, M.S, Peti, W, Page, R.
登録日2015-01-17
公開日2015-07-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.285 Å)
主引用文献Structural and Functional Analysis of the GADD34:PP1 eIF2 alpha Phosphatase.
Cell Rep, 11, 2015
8U01
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Crystal Structure of the Glycoside Hydrolase Family 2 TIM Barrel-domain Containing Protein from Phocaeicola plebeius
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, ...
著者Kim, Y, Joachimiak, G, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2023-08-28
公開日2023-09-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal Structure of the Glycoside Hydrolase Family 2 TIM Barrel-domain Containing Protein from Phocaeicola plebeius
To Be Published
8U00
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Crystal structure of metallo-beta-lactamase superfamily protein from Caulobacter vibrioides
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ...
著者Kim, Y, Maltseva, N, Endres, M, Joachimiak, A, Center for Structural Biology of Infectious Diseases (CSBID)
登録日2023-08-28
公開日2023-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of metallo-beta-lactamase superfamily protein from Caulobacter vibrioides
To Be Published
6MKS
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Cryo-EM structure of NLRC4-CARD filament
分子名称: Chimera protein of NLR family CARD domain-containing protein 4 and EGFP
著者Zheng, W, Matyszewski, M, Sohn, J, Egelman, E.H.
登録日2018-09-26
公開日2018-11-07
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structure of the NLRC4CARDfilament provides insights into how symmetric and asymmetric supramolecular structures drive inflammasome assembly.
J. Biol. Chem., 293, 2018
4S17
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The crystal structure of glutamine synthetase from Bifidobacterium adolescentis ATCC 15703
分子名称: ACETATE ION, Glutamine synthetase, MAGNESIUM ION
著者Cuff, M, Tan, K, Mack, J, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2015-01-08
公開日2015-01-28
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of glutamine synthetase from Bifidobacterium adolescentis ATCC 15703
To be Published
6MJ3
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CRYSTAL STRUCTURE OF RHESUS MACAQUE (MACACA MULATTA) IGG1 Fc Fragment-Fc-GAMMA RECEPTOR III complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Igg1 Fc, ...
著者Gohain, N, Tolbert, W.D, Pazgier, M.
登録日2018-09-20
公開日2019-08-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Decoding human-macaque interspecies differences in Fc-effector functions: The structural basis for CD16-dependent effector function in Rhesus macaques.
Front Immunol, 13, 2022
6MJO
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CRYSTAL STRUCTURE OF RHESUS MACAQUE (MACACA MULATTA) FC-GAMMA RECEPTOR III
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Low affinity immunoglobulin gamma Fc region receptor III, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Van, V, Tolbert, W.D, Pazgier, M.
登録日2018-09-21
公開日2019-11-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Decoding human-macaque interspecies differences in Fc-effector functions: The structural basis for CD16-dependent effector function in Rhesus macaques.
Front Immunol, 13, 2022
4S3D
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IspG in complex with PPi
分子名称: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, DIPHOSPHATE, FE3-S4 CLUSTER
著者Quitterer, F, Frank, A, Wang, K, Rao, G, O'Dowd, B, Li, J, Guerra, F, Abdel-Azeim, S, Bacher, A, Eppinger, J, Oldfield, E, Groll, M.
登録日2015-01-26
公開日2015-04-29
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Atomic-Resolution Structures of Discrete Stages on the Reaction Coordinate of the [Fe4S4] Enzyme IspG (GcpE).
J.Mol.Biol., 427, 2015
8HOG
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Crystal structure of Bcl-2 in complex with sonrotoclax
分子名称: Apoptosis regulator Bcl-2, ~{N}-[4-[(4-methyl-4-oxidanyl-cyclohexyl)methylamino]-3-nitro-phenyl]sulfonyl-4-[2-[(2~{S})-2-(2-propan-2-ylphenyl)pyrrolidin-1-yl]-7-azaspiro[3.5]nonan-7-yl]-2-(1~{H}-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide
著者Liu, J, Xu, M, Feng, Y, Hong, Y, Liu, Y.
登録日2022-12-10
公開日2024-01-17
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Sonrotoclax overcomes BCL2 G101V mutation-induced venetoclax resistance in preclinical models of hematologic malignancy.
Blood, 143, 2024
4TKC
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Japanese Marasmius oreades lectin complexed with mannose
分子名称: GLYCEROL, Mannose recognizing lectin, alpha-D-mannopyranose, ...
著者Noma, Y, Shimokawa, M, Maeganeku, C, Motoshima, H, Watanabe, K, Minami, Y, Yagi, F.
登録日2014-05-26
公開日2015-06-03
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献Structure of Japanese Marasmius oreades lectin complexed with mannose.
To Be Published

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件を2024-10-02に公開中

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