4TLU
 
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4S39
 | | IspG in complex with HMBPP | | 分子名称: | (2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate, 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, GLYCEROL, ... | | 著者 | Quitterer, F, Frank, A, Wang, K, Guodong, R, O'Dowd, B, Li, J, Guerra, F, Abdel-Azeim, S, Bacher, A, Eppinger, J, Oldfield, E, Groll, M. | | 登録日 | 2015-01-26 | | 公開日 | 2015-04-29 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Atomic-Resolution Structures of Discrete Stages on the Reaction Coordinate of the [Fe4S4] Enzyme IspG (GcpE).
J.Mol.Biol., 427, 2015
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7WTC
 | | Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the ground state | | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, Pyruvate carboxylase, ... | | 著者 | Chai, P, Lan, P, Wu, J, Lei, M. | | 登録日 | 2022-02-04 | | 公開日 | 2022-11-09 | | 最終更新日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA.
Mol.Cell, 82, 2022
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4TNG
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7WTB
 | | Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA | | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Chai, P, Lan, P, Wu, J, Lei, M. | | 登録日 | 2022-02-04 | | 公開日 | 2022-11-09 | | 最終更新日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA.
Mol.Cell, 82, 2022
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4TQ6
 | | Structure of a UbiA homolog from Archaeoglobus fulgidus bound to Cd2+ | | 分子名称: | CADMIUM ION, prenyltransferase | | 著者 | Huang, H, Levin, E.J, Bai, Y, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS) | | 登録日 | 2014-06-10 | | 公開日 | 2014-07-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.0678 Å) | | 主引用文献 | Structure of a Membrane-Embedded Prenyltransferase Homologous to UBIAD1.
Plos Biol., 12, 2014
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4TT4
 | | Crystal structure of ATAD2A bromodomain complexed with H3(1-21)K14Ac peptide | | 分子名称: | ATPase family AAA domain-containing protein 2, CHLORIDE ION, Histone H3(1-21)K4Ac, ... | | 著者 | Poncet-Montange, G, Zhan, Y, Bardenhagen, J, Petrocchi, A, Leo, E, Shi, X, Lee, G, Leonard, P, Geck Do, M, Cardozo, M, Palmer, W, Andersen, J, Jones, P, Ladbury, J. | | 登録日 | 2014-06-19 | | 公開日 | 2014-12-24 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2.
Biochem.J., 466, 2015
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6LXG
 | | NMR solution structure of regulatory ACT domain of the Mycobacterium tuberculosis Rel protein | | 分子名称: | GTP pyrophosphokinase | | 著者 | Shin, J, Singal, B, Manimekalai, M.S.S, Gruber, G. | | 登録日 | 2020-02-11 | | 公開日 | 2020-11-04 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Atomic structure of, and valine binding to the regulatory ACT domain of the Mycobacterium tuberculosis Rel protein.
Febs J., 288, 2021
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4TQ5
 | | Structure of a UbiA homolog from Archaeoglobus fulgidus | | 分子名称: | octyl beta-D-glucopyranoside, prenyltransferase | | 著者 | Huang, H, Levin, E.J, Bai, Y, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS) | | 登録日 | 2014-06-10 | | 公開日 | 2014-07-16 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.2023 Å) | | 主引用文献 | Structure of a Membrane-Embedded Prenyltransferase Homologous to UBIAD1.
Plos Biol., 12, 2014
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4TTU
 | | N-terminally truncated dextransucrase DSR-E from Leuconostoc mesenteroides NRRL B-1299 in complex with isomaltotriose | | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, Dextransucrase, ... | | 著者 | Brison, Y, Remaud-Simeon, M, Mourey, L, Tranier, S. | | 登録日 | 2014-06-23 | | 公開日 | 2015-07-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Structural Insights into the Carbohydrate Binding Ability of an alpha-(12) Branching Sucrase from Glycoside Hydrolase Family 70.
J.Biol.Chem., 291, 2016
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7CYI
 | | Crystal structure of Alcohol dehydrogenase 1 from Artemisia annua | | 分子名称: | Alcohol dehydrogenase 1, ZINC ION | | 著者 | Feng, X, Fan, S, Lv, G, Li, M, Wu, G, Jin, Y, Yang, Z. | | 登録日 | 2020-09-03 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Crystal structure of Alcohol dehydrogenase 1 from Artemisia annua
To Be Published
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4RNL
 | | The crystal structure of a possible galactose mutarotase from Streptomyces platensis subsp. rosaceus | | 分子名称: | GLYCEROL, PHOSPHATE ION, possible galactose mutarotase | | 著者 | Tan, K, Li, H, Endres, M, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2014-10-24 | | 公開日 | 2014-11-26 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The crystal structure of a possible galactose mutarotase from Streptomyces platensis subsp. rosaceus
To be Published
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4OJG
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7DHS
 | | Crystal Structure Analysis of the BRD4 | | 分子名称: | 6-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(1R)-1-phenylethyl]benzo[cd]indol-2-one, Bromodomain-containing protein 4 | | 著者 | Wu, T, Xiang, Q, Wang, C, Wu, C, Zhang, C, Zhang, M, Liu, Z, Zhang, Y, Xiao, L, Xu, Y. | | 登録日 | 2020-11-17 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Y06014 is a selective BET inhibitor for the treatment of prostate cancer.
Acta Pharmacol.Sin., 42, 2021
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4RSO
 | | The structure of the neurotropic AAVrh.8 viral vector | | 分子名称: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, CHLORIDE ION, Capsid protein VP1, ... | | 著者 | Halder, S, Van Vliet, K, Smith, J.K, McKenna, R, Wilson, J.M, Agbandje-McKenna, M. | | 登録日 | 2014-11-10 | | 公開日 | 2016-04-13 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structure of neurotropic adeno-associated virus AAVrh.8.
J.Struct.Biol., 192, 2015
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4RT4
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4RWZ
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7W75
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7W76
 | | Crystal structure of the K. lactis Bre1 RBD in complex with Rad6, crystal form II | | 分子名称: | E3 ubiquitin-protein ligase BRE1, GLYCEROL, SULFATE ION, ... | | 著者 | Shi, M, Zhao, J, Xiang, S. | | 登録日 | 2021-12-03 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Structural basis for the Rad6 activation by the Bre1 N-terminal domain.
Elife, 12, 2023
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6YBV
 | | Structure of a human 48S translational initiation complex - eIF2-TC | | 分子名称: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit 3, ... | | 著者 | Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V. | | 登録日 | 2020-03-17 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structure of a human 48Stranslational initiation complex.
Science, 369, 2020
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4S3C
 | | IspG in complex with Epoxide Intermediate | | 分子名称: | (3S)-1,3-dihydroxy-4-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}-2-methylbut-2-ylium, carbokation intermediate, 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, ... | | 著者 | Quitterer, F, Frank, A, Wang, K, Rao, G, O'Dowd, B, Li, J, Guerra, F, Abdel-Azeim, S, Bacher, A, Eppinger, J, Oldfield, E, Groll, M. | | 登録日 | 2015-01-26 | | 公開日 | 2015-05-06 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Atomic-Resolution Structures of Discrete Stages on the Reaction Coordinate of the [Fe4S4] Enzyme IspG (GcpE).
J.Mol.Biol., 427, 2015
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4S1A
 | | Crystal structure of a hypothetical protein Cthe_0052 from Ruminiclostridium thermocellum ATCC 27405 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CITRATE ANION, TETRAETHYLENE GLYCOL, ... | | 著者 | Filippova, E.V, Wawrzak, Z, Minasov, G, Kiryukhina, O, Endres, M, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2015-01-09 | | 公開日 | 2015-01-28 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of a hypothetical protein Cthe_0052 from Ruminiclostridium thermocellum ATCC27405
To be Published
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4S1P
 | | Shel_16390 protein, a putative SGNH hydrolase from Slackia heliotrinireducens | | 分子名称: | UNKNOWN LIGAND, Uncharacterized protein | | 著者 | Osipiuk, J, Cuff, M.E, Wu, R, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2015-01-14 | | 公開日 | 2015-01-28 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Shel_16390 protein, a putative SGNH hydrolase from Slackia heliotrinireducens
To be Published
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4TOB
 | | 1.95A resolution structure of BfrB (Q151L) from Pseudomonas aeruginosa | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Bacterioferritin, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Lovell, S, Battaile, K.P, Yao, H, Kumar, R, Eshelman, K, Rivera, M. | | 登録日 | 2014-06-05 | | 公開日 | 2015-02-11 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Concerted motions networking pores and distant ferroxidase centers enable bacterioferritin function and iron traffic.
Biochemistry, 54, 2015
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3D4X
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