6RL3
| Fragment AZ-003 binding at the p53pT387/14-3-3 sigma interface | 分子名称: | 14-3-3 protein sigma, 5-azanyl-4-phenyl-thiophene-2-carboximidamide, CHLORIDE ION, ... | 著者 | Genet, S, Wolter, M, Guillory, X, Somsen, B, Leysen, S, Patel, J, Castaldi, P, Ottmann, C. | 登録日 | 2019-05-01 | 公開日 | 2020-06-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Fragment-based Differential Targeting of PPI Stabilizer Interfaces. J.Med.Chem., 63, 2020
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2BIJ
| Crystal structure of the human protein tyrosine phosphatase PTPN5 (STEP, striatum enriched enriched Phosphatase) | 分子名称: | SULFATE ION, TYROSINE-PROTEIN PHOSPHATASE, NON-RECEPTOR TYPE 5 | 著者 | Barr, A.J, Debreczeni, J.E, Eswaran, J, Smee, C, Burgess, N, Gileadi, O, Sundstrom, M, Arrowsmith, C, Edwards, A, Knapp, S, von Delft, F. | 登録日 | 2005-01-21 | 公開日 | 2005-03-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases. Biochem. J., 395, 2006
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6RL6
| Fragment AZ-024 binding at the p53pT387/14-3-3 sigma interface | 分子名称: | 14-3-3 protein sigma, CHLORIDE ION, Cellular tumor antigen p53, ... | 著者 | Genet, S, Wolter, M, Guillory, X, Somsen, B, Leysen, S, Patel, J, Castaldi, P, Ottmann, C. | 登録日 | 2019-05-01 | 公開日 | 2020-06-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Fragment-based Differential Targeting of PPI Stabilizer Interfaces. J.Med.Chem., 63, 2020
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3P2W
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4MP4
| Crystal structure of a glutathione transferase family member from Acinetobacter baumannii, Target EFI-501785, apo structure | 分子名称: | Glutathione S-transferase, SULFATE ION | 著者 | Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Armstrong, R.N, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2013-09-12 | 公開日 | 2013-10-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.498 Å) | 主引用文献 | Crystal structure of a glutathione transferase family member from Acinetobacter baumannii, Target EFI-501785, apo structure To be Published
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1HZK
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3P34
| Polo-like kinase I Polo-box domain in complex with MQSpTPL phosphopeptide | 分子名称: | GLYCEROL, SULFATE ION, Serine/threonine-protein kinase PLK1, ... | 著者 | Sledz, P, Hyvonen, M, Abell, C. | 登録日 | 2010-10-04 | 公開日 | 2011-04-27 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | From crystal packing to molecular recognition: prediction and discovery of a binding site on the surface of polo-like kinase 1 Angew.Chem.Int.Ed.Engl., 50, 2011
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6E5F
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6I69
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3P45
| Crystal structure of apo-caspase-6 at physiological pH | 分子名称: | caspase-6 | 著者 | Mueller, I, Lamers, M.B.A.C, Ritchie, A.J, Dominguez, C, Munoz, I, Maillard, M, Kiselyov, A. | 登録日 | 2010-10-06 | 公開日 | 2011-06-15 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Crystal structures of active and inhibitor-bound human Casp6 To be Published
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6RR2
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4HT5
| CO2 concentrating mechanism protein P, CcmP form 1 | 分子名称: | CO2 concentrating mechanism protein P | 著者 | Cai, F, Sutter, M, Kerfeld, C.A. | 登録日 | 2012-10-31 | 公開日 | 2013-04-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | The structure of CcmP, a tandem bacterial microcompartment domain protein from the beta-carboxysome, forms a subcompartment within a microcompartment. J.Biol.Chem., 288, 2013
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3P5A
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1IAS
| CYTOPLASMIC DOMAIN OF UNPHOSPHORYLATED TYPE I TGF-BETA RECEPTOR CRYSTALLIZED WITHOUT FKBP12 | 分子名称: | SULFATE ION, TGF-BETA RECEPTOR TYPE I | 著者 | Huse, M, Muir, T.W, Chen, Y.-G, Kuriyan, J, Massague, J. | 登録日 | 2001-03-23 | 公開日 | 2001-10-03 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The TGF beta receptor activation process: an inhibitor- to substrate-binding switch. Mol.Cell, 8, 2001
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4HUQ
| Crystal Structure of a transporter | 分子名称: | Energy-coupling factor transporter ATP-binding protein EcfA 1, Energy-coupling factor transporter ATP-binding protein EcfA 2, Energy-coupling factor transporter transmembrane protein EcfT, ... | 著者 | Zhang, P, Xu, K, Zhang, M, Zhao, Q, Yu, F. | 登録日 | 2012-11-03 | 公開日 | 2013-04-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.998 Å) | 主引用文献 | Crystal structure of a folate energy-coupling factor transporter from Lactobacillus brevis. Nature, 497, 2013
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3P6Y
| CF Im25-CF Im68-UGUAA complex | 分子名称: | 5'-R(*UP*GP*UP*AP*A)-3', Cleavage and polyadenylation specificity factor subunit 5, Cleavage and polyadenylation specificity factor subunit 6 | 著者 | Li, H, Tong, S, Li, X, Shi, H, Gao, Y, Ge, H, Niu, L, Teng, M. | 登録日 | 2010-10-11 | 公開日 | 2010-11-03 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis of pre-mRNA recognition by the human cleavage factor Im complex To be Published
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3EEF
| Crystal structure of N-carbamoylsarcosine amidase from thermoplasma acidophilum | 分子名称: | N-carbamoylsarcosine amidase related protein, ZINC ION | 著者 | Luo, H.-B, Zheng, H, Chruszcz, M, Zimmerman, M.D, Skarina, T, Egorova, O, Savchenko, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2008-09-04 | 公開日 | 2008-09-16 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Crystal structure and molecular modeling study of N-carbamoylsarcosine amidase Ta0454 from Thermoplasma acidophilum. J.Struct.Biol., 169, 2010
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4HVM
| Crystal structure of tallysomycin biosynthesis protein TlmII | 分子名称: | SULFATE ION, TlmII | 著者 | Chang, C, Bigelow, L, Bearden, J, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2012-11-06 | 公開日 | 2012-11-21 | 最終更新日 | 2014-04-16 | 実験手法 | X-RAY DIFFRACTION (2.704 Å) | 主引用文献 | Crystal structure of tallysomycin biosynthesis protein TlmII To be Published
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3ORY
| Crystal structure of Flap endonuclease 1 from hyperthermophilic archaeon Desulfurococcus amylolyticus | 分子名称: | PHOSPHATE ION, flap endonuclease 1 | 著者 | Mase, T, Kubota, K, Miyazono, K, Kawarabayashii, Y, Tanokura, M. | 登録日 | 2010-09-08 | 公開日 | 2011-02-09 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of flap endonuclease 1 from the hyperthermophilic archaeon Desulfurococcus amylolyticus Acta Crystallogr.,Sect.F, 67, 2011
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4MK3
| Crystal structure of a glutathione transferase family member from Cupriavidus metallidurans CH34, target EFI-507362, with bound glutathione sulfinic acid (gso2h) | 分子名称: | Glutathione S-transferase, L-GAMMA-GLUTAMYL-3-SULFINO-L-ALANYLGLYCINE, MAGNESIUM ION, ... | 著者 | Toro, R, Bhosle, R, Vetting, M.W, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Armstrong, R.N, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2013-09-04 | 公開日 | 2013-09-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | 主引用文献 | Crystal structure of a glutathione transferase family member from Cupriavidus metallidurans CH34, target EFI-507362, with bound glutathione sulfinic acid (gso2h) To be published
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4MRM
| Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist phaclofen | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, ... | 著者 | Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R. | 登録日 | 2013-09-17 | 公開日 | 2013-12-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | 主引用文献 | Structural mechanism of ligand activation in human GABA(B) receptor. Nature, 504, 2013
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3OS8
| Estrogen Receptor | 分子名称: | 4-[1-benzyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol, Estrogen receptor | 著者 | Bruning, J, Parent, A.A, Gil, G, Zhao, M, Nowak, J, Pace, M.C, Smith, C.L, Afonine, P.V, Adams, P.D, Katzenellenbogen, J.A, Nettles, K.W. | 登録日 | 2010-09-08 | 公開日 | 2010-11-10 | 最終更新日 | 2021-10-06 | 実験手法 | X-RAY DIFFRACTION (2.031 Å) | 主引用文献 | Coupling of receptor conformation and ligand orientation determine graded activity. Nat.Chem.Biol., 6, 2010
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3EEY
| CRYSTAL STRUCTURE OF PUTATIVE RRNA-METHYLASE FROM Clostridium thermocellum | 分子名称: | GLYCEROL, Putative rRNA methylase, S-ADENOSYLMETHIONINE, ... | 著者 | Patskovsky, Y, Ramagopal, U.A, Toro, R, Rutter, M, Hu, S, Bain, K, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2008-09-06 | 公開日 | 2008-09-16 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structure of Rrna-Methylase from Clostridium Thermocellum To be Published
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4HX6
| Streptomyces globisporus C-1027 NADH:FAD oxidoreductase SgcE6 | 分子名称: | ACETATE ION, Oxidoreductase, SULFATE ION | 著者 | Tan, K, Bigelow, L, Clancy, S, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2012-11-09 | 公開日 | 2012-11-28 | 最終更新日 | 2016-12-07 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus. Biochemistry, 55, 2016
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6E6S
| 1.45 A resolution structure of the C-terminally truncated [2Fe-2S] ferredoxin (Bfd) R26E/K46Y mutant from Pseudomonas aeruginosa | 分子名称: | Bacterioferritin-associated ferredoxin, FE2/S2 (INORGANIC) CLUSTER | 著者 | Lovell, S, Wijerathne, H, Battaile, K.P, Yao, H, Wang, Y, Rivera, M. | 登録日 | 2018-07-25 | 公開日 | 2018-09-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Bfd, a New Class of [2Fe-2S] Protein That Functions in Bacterial Iron Homeostasis, Requires a Structural Anion Binding Site. Biochemistry, 57, 2018
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