2BIJ

Crystal structure of the human protein tyrosine phosphatase PTPN5 (STEP, striatum enriched enriched Phosphatase)

Summary for 2BIJ

Entry DOI	10.2210/pdb2bij/pdb
Descriptor	TYROSINE-PROTEIN PHOSPHATASE, NON-RECEPTOR TYPE 5, SULFATE ION (3 entities in total)
Functional Keywords	ptpn5, step, phosphatase, hydrolase
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	35300.91
Authors	Barr, A.J.,Debreczeni, J.E.,Eswaran, J.,Smee, C.,Burgess, N.,Gileadi, O.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Knapp, S.,von Delft, F. (deposition date: 2005-01-21, release date: 2005-03-17, Last modification date: 2023-12-13)
Primary citation	Eswaran, J.,von Kries, J.P.,Marsden, B.,Longman, E.,Debreczeni, J.E.,Ugochukwu, E.,Turnbull, A.,Lee, W.H.,Knapp, S.,Barr, A.J. Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases. Biochem. J., 395:483-491, 2006 Cited by PubMed: 16441242 DOI: 10.1042/BJ20051931 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation