5OWL
| Low salt structure of human protein kinase CK2alpha in complex with 3-aminopropyl-4,5,6,7-tetrabromobenzimidazol | 分子名称: | 3-[4,5,6,7-tetrakis(bromanyl)benzimidazol-1-yl]propan-1-amine, Casein kinase II subunit alpha, GLYCEROL, ... | 著者 | Niefind, K, Bretner, M, Chojnacki, C. | 登録日 | 2017-09-01 | 公開日 | 2018-07-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Biological properties and structural study of new aminoalkyl derivatives of benzimidazole and benzotriazole, dual inhibitors of CK2 and PIM1 kinases. Bioorg. Chem., 80, 2018
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5FXS
| IGFR-1R complex with a pyrimidine inhibitor. | 分子名称: | 2-[4-[4-[[(6Z)-5-chloranyl-6-pyrazolo[1,5-a]pyridin-3-ylidene-1H-pyrimidin-2-yl]amino]-3,5-dimethyl-pyrazol-1-yl]piperidin-1-yl]-N,N-dimethyl-ethanamide, ACETATE ION, INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR | 著者 | Degorce, S, Boyd, S, Curwen, J, Ducray, R, Halsall, C, Jones, C, Lach, F, Lenz, E, Pass, M, Pass, S, Trigwell, C, Norman, R, Phillips, C. | 登録日 | 2016-03-02 | 公開日 | 2016-10-19 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery of a Potent, Selective, Orally Bioavailable, and Efficacious Novel 2-(Pyrazol-4-ylamino)-pyrimidine Inhibitor of the Insulin-like Growth Factor-1 Receptor (IGF-1R). J. Med. Chem., 59, 2016
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3UT5
| Tubulin-Colchicine-Ustiloxin: Stathmin-like domain complex | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Ranaivoson, F.M, Gigant, B, Knossow, M. | 登録日 | 2011-11-25 | 公開日 | 2012-08-01 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | Structural plasticity of tubulin assembly probed by vinca-domain ligands. Acta Crystallogr.,Sect.D, 68, 2012
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5KOA
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2O98
| Structure of the 14-3-3 / H+-ATPase plant complex | 分子名称: | 14-3-3-like protein C, FUSICOCCIN, Plasma membrane H+ ATPase, ... | 著者 | Ottmann, C, Weyand, M, Wittinghofer, A, Oecking, C. | 登録日 | 2006-12-13 | 公開日 | 2007-04-03 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of a 14-3-3 coordinated hexamer of the plant plasma membrane H+ -ATPase by combining X-ray crystallography and electron cryomicroscopy Mol.Cell, 25, 2007
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2XKI
| Aquo-met structure of C.lacteus mini-Hb | 分子名称: | GLYCEROL, NEURAL HEMOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Pesce, A, Nardini, M, Dewilde, S, Capece, L, Marti, M.A, Congia, S, Salter, M.D, Blouin, G.C, Estrin, D.A, Ascenzi, P, Moens, L, Bolognesi, M, Olson, J.S. | 登録日 | 2010-07-08 | 公開日 | 2010-12-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Ligand Migration in the Apolar Tunnel of Cerebratulus Lacteus Mini-Hemoglobin. J.Biol.Chem., 286, 2011
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2XNE
| Structure of Aurora-A bound to an imidazopyrazine inhibitor | 分子名称: | 3-chloro-N-(4-morpholin-4-ylphenyl)-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine, SERINE/THREONINE-PROTEIN KINASE 6 | 著者 | Kosmopoulou, M, Bayliss, R. | 登録日 | 2010-08-02 | 公開日 | 2010-09-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-based design of imidazo[1,2-a]pyrazine derivatives as selective inhibitors of Aurora-A kinase in cells. Bioorg. Med. Chem. Lett., 20, 2010
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6XLY
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2XO7
| Crystal structure of a dA:O-allylhydroxylamine-dC basepair in complex with fragment DNA polymerase I from Bacillus stearothermophilus | 分子名称: | 5'-D(*AP*GP*GP*AP*AP*TP*GP*GP*TP*CP*A)-3', 5'-D(*GP*AP*CP*CP*AP*TP*47C*CP*CP*T)-3', DNA POLYMERASE I, ... | 著者 | Muenzel, M, Lercher, L, Mueller, M, Carell, T. | 登録日 | 2010-08-10 | 公開日 | 2010-09-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Chemical Discrimination between Dc and 5Medc Via Their Hydroxylamine Adducts Nucleic Acids Res., 38, 2010
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5KQU
| Directed Evolution of Transaminases By Ancestral Reconstruction. Using Old Proteins for New Chemistries | 分子名称: | 4-aminobutyrate transaminase, PYRIDOXAL-5'-PHOSPHATE | 著者 | Wilding, M, Newman, J, Peat, T.S, Scott, C. | 登録日 | 2016-07-06 | 公開日 | 2017-07-12 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction Green Chemistry, 19, 2017
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6XE0
| Cryo-EM structure of NusG-CTD bound to 70S ribosome (30S: NusG-CTD fragment) | 分子名称: | 16s rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Washburn, R, Zuber, P, Sun, M, Hashem, Y, Shen, B, Li, W, Harvey, S, Acosta-Reyes, F.J, Knauer, S.H, Frank, J, Gottesman, M.E. | 登録日 | 2020-06-11 | 公開日 | 2020-07-29 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | 主引用文献 | Escherichia coli NusG Links the Lead Ribosome with the Transcription Elongation Complex. Iscience, 23, 2020
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7RSL
| Seipin forms a flexible cage at lipid droplet formation sites | 分子名称: | Seipin | 著者 | Arlt, H, Sui, X, Folger, B, Adams, C, Chen, X, Remme, R, Hamprecht, F.A, DiMaio, F, Liao, M, Goodman, J.M, Farese Jr, R.V, Walther, T.C. | 登録日 | 2021-08-11 | 公開日 | 2022-02-09 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | 主引用文献 | Seipin forms a flexible cage at lipid droplet formation sites. Nat.Struct.Mol.Biol., 29, 2022
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6X60
| ClpP2 from Chlamydia trachomatis with resolved handle loop | 分子名称: | ATP-dependent Clp protease proteolytic subunit 2 | 著者 | Azadmanesh, J, Struble, L.R, Seleem, M.A, Ouellette, S, Conda-Sheridan, M, Borgstahl, G.E.O. | 登録日 | 2020-05-27 | 公開日 | 2020-06-03 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | ClpP2 from Chlamydia trachomatis with resolved handle loop To Be Published
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3UXL
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8OST
| Structure of human terminal uridylyltransferase 4 (TUT4, ZCCHC11) in complex with pre-let7g miRNA and Lin28A | 分子名称: | Protein lin-28 homolog A, Terminal uridylyltransferase 4, ZINC ION, ... | 著者 | Gilbert, R.J, Yi, G, Ye, M. | 登録日 | 2023-04-20 | 公開日 | 2024-07-17 | 最終更新日 | 2024-09-25 | 実験手法 | ELECTRON MICROSCOPY (3.69 Å) | 主引用文献 | Structural basis for activity switching in polymerases determining the fate of let-7 pre-miRNAs. Nat.Struct.Mol.Biol., 31, 2024
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2XYV
| Crystal structure of the nsp16 nsp10 SARS coronavirus complex | 分子名称: | CHLORIDE ION, MAGNESIUM ION, NON-STRUCTURAL PROTEIN 10, ... | 著者 | Decroly, E, Debarnot, C, Ferron, F, Bouvet, M, Coutard, B, Imbert, I, Gluais, L, Papageorgiou, N, Ortiz-Lombardia, M, Lescar, J, Canard, B. | 登録日 | 2010-11-19 | 公開日 | 2011-10-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Crystal Structure and Functional Analysis of the Sars-Coronavirus RNA CAP 2'-O-Methyltransferase Nsp10/Nsp16 Complex. Plos Pathog., 7, 2011
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6XG1
| Class C beta-lactamase from Escherichia coli | 分子名称: | 1,2-ETHANEDIOL, Beta-lactamase | 著者 | Chang, C, Maltseva, N, Endres, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-06-16 | 公開日 | 2020-06-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | 主引用文献 | Class C beta-lactamase from Escherichia coli To Be Published
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8OPP
| Structure of human terminal uridylyltransferase 7 (hTUT7/ZCCHC6) bound with pre-let7g miRNA and UTPalphaS | 分子名称: | RNA (25-MER), Terminal uridylyltransferase 7, [[(2~{R},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-sulfanyl-phosphoryl] phosphono hydrogen phosphate | 著者 | Yi, G, Ye, M, Gilbert, R.J. | 登録日 | 2023-04-07 | 公開日 | 2024-07-24 | 最終更新日 | 2024-09-25 | 実験手法 | ELECTRON MICROSCOPY (3.76 Å) | 主引用文献 | Structural basis for activity switching in polymerases determining the fate of let-7 pre-miRNAs. Nat.Struct.Mol.Biol., 31, 2024
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8OPS
| Human terminal uridylyltransferase 7 (TUT7/ZCCHC6) bound with pre-let7g miRNA and Lin28A - complex 1 | 分子名称: | Protein lin-28 homolog A, RNA (71-MER) Let7g, Terminal uridylyltransferase 7, ... | 著者 | Yi, G, Ye, M, Gilbert, R.J. | 登録日 | 2023-04-08 | 公開日 | 2024-07-24 | 最終更新日 | 2024-09-25 | 実験手法 | ELECTRON MICROSCOPY (3.82 Å) | 主引用文献 | Structural basis for activity switching in polymerases determining the fate of let-7 pre-miRNAs. Nat.Struct.Mol.Biol., 31, 2024
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5HNK
| Crystal structure of T5Fen in complex intact substrate and metal ions. | 分子名称: | DNA (5'-D(*AP*AP*AP*AP*GP*CP*GP*TP*AP*CP*GP*C)-3'), Exodeoxyribonuclease, GLYCEROL, ... | 著者 | Almalki, F.A, Feng, M, Zhang, J, Sedelnikova, S.E, Rafferty, J.B, Sayers, J.R, Artymiuk, P.J. | 登録日 | 2016-01-18 | 公開日 | 2016-06-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Direct observation of DNA threading in flap endonuclease complexes. Nat.Struct.Mol.Biol., 23, 2016
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5I87
| Crystal structure of BT-CD domains of human acetyl-CoA carboxylase | 分子名称: | BT-CD domains of human acetyl-CoA carboxylase, CADMIUM ION | 著者 | Stuttfeld, E, Hunkeler, M, Hagmann, A, Imseng, S, Maier, T. | 登録日 | 2016-02-18 | 公開日 | 2016-04-20 | 最終更新日 | 2016-04-27 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | The dynamic organization of fungal acetyl-CoA carboxylase. Nat Commun, 7, 2016
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2W93
| Crystal structure of the Saccharomyces cerevisiae pyruvate decarboxylase variant E477Q in complex with the surrogate pyruvamide | 分子名称: | (1S,2S)-1-amino-1,2-dihydroxypropan-1-olate, MAGNESIUM ION, PYRUVATE DECARBOXYLASE ISOZYME 1, ... | 著者 | Kutter, S, Weiss, M.S, Konig, S. | 登録日 | 2009-01-21 | 公開日 | 2009-02-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Allosteric Activation of Pyruvate Decarboxylases. A Never-Ending Story. J.Mol.Catal., B Enzym., 61, 2014
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8OPT
| Human terminal uridylyltransferase 7 (TUT7/ZCCHC6) bound with pre-let7g miRNA and Lin28A - complex 2 | 分子名称: | Protein lin-28 homolog A, RNA (53-MER), Terminal uridylyltransferase 7, ... | 著者 | Yi, G, Ye, M, Gilbert, R.J. | 登録日 | 2023-04-08 | 公開日 | 2024-07-24 | 最終更新日 | 2024-09-25 | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | 主引用文献 | Structural basis for activity switching in polymerases determining the fate of let-7 pre-miRNAs. Nat.Struct.Mol.Biol., 31, 2024
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5OON
| Structure of Undecaprenyl-Pyrophosphate Phosphatase, BacA | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MERCURY (II) ION, ... | 著者 | Huang, C.-Y, Olieric, V, Warshamanage, R, Wang, M, Howe, N, Ghachi, M.E.I, Weichert, D, Kerff, F, Stansfeld, P, Touze, T, Caffrey, M. | 登録日 | 2017-08-08 | 公開日 | 2018-03-21 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of undecaprenyl-pyrophosphate phosphatase and its role in peptidoglycan biosynthesis. Nat Commun, 9, 2018
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5I1U
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