5H41
 
 | | Crystal Structure of 1,2-beta-oligoglucan phosphorylase from Lachnoclostridium phytofermentans in complex with sophorose, isofagomine, sulfate ion | | 分子名称: | 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, SULFATE ION, Uncharacterized protein, ... | | 著者 | Nakajima, M, Tanaka, N, Furukawa, N, Nihira, T, Kodutsumi, Y, Takahashi, Y, Sugimoto, N, Miyanaga, A, Fushinobu, S, Taguchi, H, Nakai, H. | | 登録日 | 2016-10-28 | | 公開日 | 2017-03-01 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Mechanistic insight into the substrate specificity of 1,2-beta-oligoglucan phosphorylase from Lachnoclostridium phytofermentans
Sci Rep, 7, 2017
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2M4X
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6SOF
 | | human insulin receptor ectodomain bound by 4 insulin | | 分子名称: | Insulin, Insulin receptor | | 著者 | Gutmann, T, Schaefer, I.B, Poojari, C.S, Vattulainen, I, Strauss, M, Coskun, U. | | 登録日 | 2019-08-29 | | 公開日 | 2019-11-13 | | 最終更新日 | 2020-05-27 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Cryo-EM structure of the complete and ligand-saturated insulin receptor ectodomain.
J.Cell Biol., 219, 2020
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3VSM
 | | The crystal structure of novel chondroition lyase ODV-E66, baculovirus envelope protein | | 分子名称: | GLYCEROL, Occlusion-derived virus envelope protein E66 | | 著者 | Kawaguchi, Y, Sugiura, N, Kimata, K, Kimura, M, Kakuta, Y. | | 登録日 | 2012-04-27 | | 公開日 | 2013-05-22 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The crystal structure of novel chondroition lyase ODV-E66, baculovirus envelope protein
To be Published
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7SCX
 | | KRAS full-length G12V in complex with RGL1 Ras association domain | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Isoform 2B of GTPase KRas, MAGNESIUM ION, ... | | 著者 | Eves, B.J, Kuntz, D.A, Ikura, M, Marshall, C.B. | | 登録日 | 2021-09-29 | | 公開日 | 2022-05-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Structures of RGL1 RAS-Association Domain in Complex with KRAS and the Oncogenic G12V Mutant.
J.Mol.Biol., 434, 2022
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3A4D
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8JOR
 | | Structure of an acyltransferase involved in mannosylerythritol lipid formation from Pseudozyma tsukubaensis in type A crystal | | 分子名称: | Acyltransferase, PENTAETHYLENE GLYCOL | | 著者 | Nakamichi, Y, Saika, A, Watanabe, M, Fujii, T, Morita, T. | | 登録日 | 2023-06-08 | | 公開日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structural identification of catalytic His158 of PtMAC2p from Pseudozyma tsukubaensis , an acyltransferase involved in mannosylerythritol lipids formation.
Front Bioeng Biotechnol, 11, 2023
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8JOS
 | | Structure of an acyltransferase involved in mannosylerythritol lipid formation from Pseudozyma tsukubaensis in type B crystal | | 分子名称: | Acyltransferase, CHLORIDE ION, TRIETHYLENE GLYCOL | | 著者 | Nakamichi, Y, Saika, A, Watanabe, M, Fujii, T, Morita, T. | | 登録日 | 2023-06-08 | | 公開日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Structural identification of catalytic His158 of PtMAC2p from Pseudozyma tsukubaensis , an acyltransferase involved in mannosylerythritol lipids formation.
Front Bioeng Biotechnol, 11, 2023
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6YFC
 | | Virus-like particle of bacteriophage AVE019 | | 分子名称: | CALCIUM ION, coat protein | | 著者 | Rumnieks, J, Kalnins, G, Sisovs, M, Lieknina, I, Tars, K. | | 登録日 | 2020-03-26 | | 公開日 | 2020-09-02 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.246 Å) | | 主引用文献 | Three-dimensional structure of 22 uncultured ssRNA bacteriophages: Flexibility of the coat protein fold and variations in particle shapes.
Sci Adv, 6, 2020
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5H0Z
 | | Crystal structure of P113A mutated human transthyretin | | 分子名称: | CHLORIDE ION, SULFATE ION, Transthyretin | | 著者 | Yokoyama, T, Hanawa, Y, Obita, T, Mizuguchi, M. | | 登録日 | 2016-10-07 | | 公開日 | 2017-06-14 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.735 Å) | | 主引用文献 | Stability and crystal structures of His88 mutant human transthyretins
FEBS Lett., 591, 2017
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3A4U
 | | Crystal structure of MCFD2 in complex with carbohydrate recognition domain of ERGIC-53 | | 分子名称: | CALCIUM ION, GLYCEROL, Multiple coagulation factor deficiency protein 2, ... | | 著者 | Nishio, M, Kamiya, Y, Mizushima, T, Wakatsuki, S, Sasakawa, H, Yamamoto, K, Uchiyama, S, Noda, M, McKay, A.R, Fukui, K, Hauri, H.P, Kato, K. | | 登録日 | 2009-07-17 | | 公開日 | 2010-01-05 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Structural basis for the cooperative interplay between the two causative gene products of combined factor V and factor VIII deficiency.
Proc.Natl.Acad.Sci.USA, 107, 2010
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5GOB
 | | Lys6-linked di-ubiquitin | | 分子名称: | D-ubiquitin, Ubiquitin | | 著者 | Gao, S, Pan, M, Zheng, Y, Liu, L. | | 登録日 | 2016-07-26 | | 公開日 | 2016-11-02 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.153 Å) | | 主引用文献 | Monomer/Oligomer Quasi-Racemic Protein Crystallography
J.Am.Chem.Soc., 138, 2016
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4J1E
 | | CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH 5-Cyano-pyridine-2-carboxylic acid [3-((4S,6S)-2-amino-4-fluoromethyl-6-trifluoromethyl-5,6-dihydro-4H-[1,3]oxazin-4-yl)-4-fluoro-phenyl]-amide | | 分子名称: | Beta-secretase 1, DIMETHYL SULFOXIDE, N-{3-[(4S,6S)-2-amino-4-(fluoromethyl)-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide, ... | | 著者 | Kuglstatter, A, Stihle, M. | | 登録日 | 2013-02-01 | | 公開日 | 2013-05-01 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | beta-Secretase (BACE1) Inhibitors with High In Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer s Disease
J.Med.Chem., 56, 2013
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6YA0
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4J23
 | | Low resolution crystal structure of the FGFR2D2D3/FGF1/SR128545 complex | | 分子名称: | Fibroblast growth factor 1, Fibroblast growth factor receptor 2 | | 著者 | Kudlinzki, D, Saxena, K, Sreeramulu, S, Schieborr, U, Dreyer, M, Schreuder, H, Schwalbe, H. | | 登録日 | 2013-02-04 | | 公開日 | 2014-02-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.882 Å) | | 主引用文献 | Molecular mechanism of SSR128129E, an extracellularly acting, small-molecule, allosteric inhibitor of FGF receptor signaling.
Cancer Cell, 23, 2013
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5JWT
 | | T4 Lysozyme L99A/M102Q with Benzene Bound | | 分子名称: | BENZENE, Endolysin | | 著者 | Lee, H, Fischer, M, Shoichet, B.K, Liu, S.-Y. | | 登録日 | 2016-05-12 | | 公開日 | 2016-09-21 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | | 主引用文献 | Hydrogen Bonding of 1,2-Azaborines in the Binding Cavity of T4 Lysozyme Mutants: Structures and Thermodynamics.
J.Am.Chem.Soc., 138, 2016
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6YHV
 | | Structural insights into Pseudomonas aeruginosa Type six secretion system exported effector 8: unliganded Tse8 | | 分子名称: | COPPER (II) ION, Tse8 | | 著者 | Sainz-Polo, M.A, Capuni, R, Pretre, G, Gonzalez-Magana, A, Lucas, M, Altuna, J, Montanchez, I, Fucini, P, Albesa-Jove, D. | | 登録日 | 2020-03-31 | | 公開日 | 2020-11-04 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.893 Å) | | 主引用文献 | Structural insights into Pseudomonas aeruginosaType six secretion system exported effector 8.
J.Struct.Biol., 212, 2020
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7SD4
 | | SARS-CoV-2 Nucleocapsid N-terminal domain (N-NTD) protein | | 分子名称: | Nucleoprotein | | 著者 | Sarkar, S, Runge, B, Russell, R.W, Calero, D, Zeinalilathori, S, Quinn, C.M, Lu, M, Calero, G, Gronenborn, A.M, Polenova, T. | | 登録日 | 2021-09-29 | | 公開日 | 2022-06-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | Atomic-Resolution Structure of SARS-CoV-2 Nucleocapsid Protein N-Terminal Domain.
J.Am.Chem.Soc., 144, 2022
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6YIF
 | | Structure of Chromosomal Passenger Complex (CPC) bound to phosphorylated Histone 3 peptide at 1.8 A. | | 分子名称: | Baculoviral IAP repeat-containing protein 5, Borealin, Inner centromere protein, ... | | 著者 | Serena, M, Elliott, P.R, Barr, F.A. | | 登録日 | 2020-04-01 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Molecular basis of MKLP2-dependent Aurora B transport from chromatin to the anaphase central spindle.
J.Cell Biol., 219, 2020
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7RZY
 | | CryoEM structure of Vibrio cholerae transposon Tn6677 AAA+ ATPase TnsC | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Tn6677 Vibrio cholerae transposon TnsC (VchTnsC) | | 著者 | Hoffmann, F.T, Kim, M, Beh, L.Y, Wang, J, Vo, P.L.H, Gelsinger, D.R, Acree, C, Mohabir, J.T, Fernandez, I.S, Sternberg, S.H. | | 登録日 | 2021-08-28 | | 公開日 | 2022-06-08 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Selective TnsC recruitment enhances the fidelity of RNA-guided transposition.
Nature, 609, 2022
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6YIN
 | | Crystal structure of the first bromodomain of BRD4 in complex with a benzo-diazepine ligand | | 分子名称: | (4~{R})-~{N}-[3-(7-methoxy-3,4-dihydro-2~{H}-quinolin-1-yl)propyl]-4-methyl-2-oxidanylidene-1,3,4,5-tetrahydro-1,5-benzodiazepine-6-carboxamide, Bromodomain-containing protein 4 | | 著者 | Picaud, S, Brand, M, Tobias, K, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Conway, S, Filippakopoulos, P. | | 登録日 | 2020-04-01 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Crystal structure of the first bromodomain of BRD4 in complex with a benzo-diazepine ligand
To Be Published
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3A8G
 | | Crystal structure of Nitrile Hydratase mutant S113A complexed with Trimethylacetonitrile | | 分子名称: | 2,2-dimethylpropanenitrile, FE (III) ION, MAGNESIUM ION, ... | | 著者 | Yamanaka, Y, Hashimoto, K, Ohtaki, A, Noguchi, K, Yohda, M, Odaka, M. | | 登録日 | 2009-10-06 | | 公開日 | 2010-04-14 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (1.11 Å) | | 主引用文献 | Kinetic and structural studies on roles of the serine ligand and a strictly conserved tyrosine residue in nitrile hydratase
J.Biol.Inorg.Chem., 15, 2010
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3AAA
 | | Crystal Structure of Actin capping protein in complex with V-1 | | 分子名称: | F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1 and 2, ISOPROPYL ALCOHOL, ... | | 著者 | Takeda, S, Minakata, S, Narita, A, Kitazawa, M, Yamakuni, T, Maeda, Y, Nitanai, Y. | | 登録日 | 2009-11-12 | | 公開日 | 2010-08-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Two distinct mechanisms for actin capping protein regulation--steric and allosteric inhibition
Plos Biol., 8, 2010
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3A14
 | | Crystal structure of DXR from Thermotoga maritima, in complex with NADPH | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1-deoxy-D-xylulose 5-phosphate reductoisomerase, MAGNESIUM ION, ... | | 著者 | Takenoya, M, Ohtaki, A, Noguchi, K, Sasaki, Y, Ohsawa, K, Yohda, M, Yajima, S. | | 登録日 | 2009-03-25 | | 公開日 | 2010-04-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of 1-deoxy-d-xylulose 5-phosphate reductoisomerase from the hyperthermophile Thermotoga maritima for insights into the coordination of conformational changes and an inhibitor binding.
J.Struct.Biol., 2010
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8JOK
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