7NTP
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![BU of 7ntp by Molmil](/molmil-images/mine/7ntp) | Human myelin P2 mutant V115A | 分子名称: | Myelin P2 protein, PALMITIC ACID | 著者 | Uusitalo, M, Ruskamo, S, Kursula, P. | 登録日 | 2021-03-10 | 公開日 | 2021-09-01 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Human myelin protein P2: from crystallography to time-lapse membrane imaging and neuropathy-associated variants. Febs J., 288, 2021
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6NCG
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![BU of 6ncg by Molmil](/molmil-images/mine/6ncg) | Crystal Structure of Human Vaccinia-related kinase 2 (VRK-2) bound to pyridin-benzenesulfonamide inhibitor | 分子名称: | 4-[6-amino-5-(3,5-difluoro-4-hydroxyphenyl)pyridin-3-yl]benzene-1-sulfonamide, SULFATE ION, Serine/threonine-protein kinase VRK2 | 著者 | dos Reis, C.V, Chiodi, C.G, de Souza, G.P, Guimaraes, C, Mascarello, A, Gama, F, Ferreira, M, Counago, R.M, Massirer, K.B, Elkins, J.M, Arruda, P, Edwards, A.M, Structural Genomics Consortium (SGC) | 登録日 | 2018-12-11 | 公開日 | 2019-01-16 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Crystal Structure of Human Vaccinia-related kinase 2 (VRK-2) bound to pyridin-benzenesulfonamide inhibitor To Be Published
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6QBU
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![BU of 6qbu by Molmil](/molmil-images/mine/6qbu) | Crystal structure of Porcine Pancreatic Elastase (PPE) in complex with the 3-Oxo-beta-Sultam inhibitor LMC188 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Chymotrypsin-like elastase family member 1, PHOSPHATE ION, ... | 著者 | Brito, J.A, Almeida, V.T, Carvalho, L.M, Moreira, R, Archer, M. | 登録日 | 2018-12-21 | 公開日 | 2020-04-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | 3-Oxo-beta-sultam as a Sulfonylating Chemotype for Inhibition of Serine Hydrolases and Activity-Based Protein Profiling. Acs Chem.Biol., 15, 2020
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7ODX
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6NCQ
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6VYY
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![BU of 6vyy by Molmil](/molmil-images/mine/6vyy) | Escherichia coli transcription-translation complex C5 (TTC-C5) containing mRNA with a 21 nt long spacer, NusG, and fMet-tRNAs at E-site and P-site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | 登録日 | 2020-02-27 | 公開日 | 2020-09-02 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (9.9 Å) | 主引用文献 | Structural basis of transcription-translation coupling. Science, 369, 2020
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1XS6
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![BU of 1xs6 by Molmil](/molmil-images/mine/1xs6) | dCTP deaminase from Escherichia coli. E138A mutant enzyme in complex with dUTP | 分子名称: | DEOXYURIDINE-5'-TRIPHOSPHATE, Deoxycytidine triphosphate deaminase, MAGNESIUM ION | 著者 | Johansson, E, Fano, M, Bynck, J.H, Neuhard, J, Larsen, S, Sigurskjold, B.W, Christensen, U, Willemoes, M. | 登録日 | 2004-10-18 | 公開日 | 2004-12-21 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes J.Biol.Chem., 280, 2005
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1RNF
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![BU of 1rnf by Molmil](/molmil-images/mine/1rnf) | X-RAY CRYSTAL STRUCTURE OF UNLIGANDED HUMAN RIBONUCLEASE 4 | 分子名称: | PROTEIN (RIBONUCLEASE 4) | 著者 | Terzyan, S.S, Peracaula, R, De Llorens, R, Tsushima, Y, Yamada, H, Seno, M, Gomis-Rueth, F.X, Coll, M. | 登録日 | 1998-10-29 | 公開日 | 1999-10-29 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The three-dimensional structure of human RNase 4, unliganded and complexed with d(Up), reveals the basis for its uridine selectivity. J.Mol.Biol., 285, 1999
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1XSN
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![BU of 1xsn by Molmil](/molmil-images/mine/1xsn) | Crystal Structure of human DNA polymerase lambda in complex with a one nucleotide DNA gap and ddTTP | 分子名称: | 1,2-ETHANEDIOL, 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*AP*GP*TP*AP*(2DT))-3', ... | 著者 | Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Kunkel, T.A, Pedersen, L.C. | 登録日 | 2004-10-19 | 公開日 | 2005-01-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | A closed conformation for the Pol lambda catalytic cycle. Nat.Struct.Mol.Biol., 12, 2005
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6VYW
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![BU of 6vyw by Molmil](/molmil-images/mine/6vyw) | Escherichia coli transcription-translation complex C3 (TTC-C3) containing mRNA with a 27 nt long spacer, NusG, and fMet-tRNAs at E-site and P-site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | 登録日 | 2020-02-27 | 公開日 | 2020-09-02 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (7 Å) | 主引用文献 | Structural basis of transcription-translation coupling. Science, 369, 2020
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6Q6T
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6VZU
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![BU of 6vzu by Molmil](/molmil-images/mine/6vzu) | TTLL6 bound to alpha-elongation analog | 分子名称: | (2~{S})-2-[[[(1~{R})-1-acetamido-4-oxidanyl-4-oxidanylidene-butyl]-oxidanyl-phosphoryl]methyl]pentanedioic acid, (2~{S})-2-[[[(1~{R})-1-acetamido-4-oxidanyl-4-oxidanylidene-butyl]-phosphonooxy-phosphoryl]methyl]pentanedioic acid, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Mahalingan, K.K, Keenen, E.K, Strickland, M, Li, Y, Liu, Y, Ball, H.B, Tanner, M.E, Tjandra, N, Roll-Mecak, A. | 登録日 | 2020-02-28 | 公開日 | 2020-08-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes. Nat.Struct.Mol.Biol., 27, 2020
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1XT4
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![BU of 1xt4 by Molmil](/molmil-images/mine/1xt4) | Urate Oxidase From Aspergillus Flavus Complexed With Guanine | 分子名称: | GUANINE, Uricase | 著者 | Retailleau, P, Colloc'h, N, Vivares, D, Bonnete, F, Castro, B, El Hajji, M, Prange, T. | 登録日 | 2004-10-21 | 公開日 | 2005-03-22 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Urate oxidase from Aspergillus flavus: new crystal-packing contacts in relation to the content of the active site. Acta Crystallogr.,Sect.D, 61, 2005
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6NIO
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![BU of 6nio by Molmil](/molmil-images/mine/6nio) | Crystal Structure of the Molybdate Transporter Periplasmic Protein ModA from Yersinia pestis | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ACETIC ACID, FORMIC ACID, ... | 著者 | Kim, Y, Joachimiak, G, Maltseva, N, Endres, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2018-12-31 | 公開日 | 2019-01-16 | 最終更新日 | 2019-12-18 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Crystal Structure of the Molybdate Transporter Periplasmic Protein ModA from Yersinia pestis To Be Published
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6QCZ
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![BU of 6qcz by Molmil](/molmil-images/mine/6qcz) | MloK1 model from single particle analysis of 2D crystals, class 3 (intermediate extended conformation) | 分子名称: | Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION | 著者 | Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H. | 登録日 | 2018-12-31 | 公開日 | 2019-04-24 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM. Nat Commun, 10, 2019
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6W1D
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![BU of 6w1d by Molmil](/molmil-images/mine/6w1d) | Structure of human mitochondrial complex Nfs1-ISCU2 (WT)-ISD11 with E.coli ACP1 at 1.8 A resolution (NIAU)2 | 分子名称: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ... | 著者 | Boniecki, M.T, Cygler, M. | 登録日 | 2020-03-04 | 公開日 | 2020-03-18 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.795 Å) | 主引用文献 | The essential function of ISCU2 and its conserved N-terminus in Fe/S cluster biogenesis To Be Published
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6QD3
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![BU of 6qd3 by Molmil](/molmil-images/mine/6qd3) | MloK1 model from single particle analysis of 2D crystals, class 7 (intermediate conformation) | 分子名称: | Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION | 著者 | Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H. | 登録日 | 2018-12-31 | 公開日 | 2019-04-24 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (5 Å) | 主引用文献 | Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM. Nat Commun, 10, 2019
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6NER
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![BU of 6ner by Molmil](/molmil-images/mine/6ner) | Synthetic Haliangium ochraceum BMC shell | 分子名称: | BMC-H tandem fusion protein, SULFATE ION | 著者 | Sutter, M, McGuire, S, Aussignargues, C, Kerfeld, C.A. | 登録日 | 2018-12-18 | 公開日 | 2019-04-03 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.59 Å) | 主引用文献 | Structural Characterization of a Synthetic Tandem-Domain Bacterial Microcompartment Shell Protein Capable of Forming Icosahedral Shell Assemblies. ACS Synth Biol, 8, 2019
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1KP4
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6NWP
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![BU of 6nwp by Molmil](/molmil-images/mine/6nwp) | Chronic traumatic encephalopathy Type I Tau filament | 分子名称: | Microtubule-associated protein tau | 著者 | Falcon, B, Zivanov, J, Zhang, W, Murzin, A.G, Garringer, H.J, Vidal, R, Crowther, R.A, Newell, K.L, Ghetti, B, Goedert, M, Scheres, H.W. | 登録日 | 2019-02-07 | 公開日 | 2019-03-27 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules. Nature, 568, 2019
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1XKQ
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![BU of 1xkq by Molmil](/molmil-images/mine/1xkq) | Crystal Structure of Short-Chain Dehydrogenase/Reductase of unknown Function from Caenorhabditis Elegans with Cofactor | 分子名称: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, short-chain reductase family member (5D234) | 著者 | Schormann, N, Zhou, J, Karpova, E, Zhang, Y, Symersky, J, Bunzel, B, Huang, W.-Y, Arabshahi, A, Qiu, S, Luan, C.-H, Gray, R, Carson, M, Tsao, J, Luo, M, Johnson, D, Lu, S, Lin, G, Luo, D, Cao, Z, Li, S, McKinstry, A, Shang, Q, Chen, Y.-J, Bray, T, Nagy, L, DeLucas, L, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2004-09-29 | 公開日 | 2004-10-12 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of Short-Chain Dehydrogenase/Reductase of unknown Function from Caenorhabditis Elegans with Cofactor To be Published
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6JZY
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![BU of 6jzy by Molmil](/molmil-images/mine/6jzy) | Crystal structure of AAR with NADPH and stearyl in complex with ADO binding a long chain carbohydrate | 分子名称: | Aldehyde decarbonylase, FE (II) ION, HEXADECAN-1-OL, ... | 著者 | Zhang, H.M, Li, M, Gao, Y. | 登録日 | 2019-05-04 | 公開日 | 2020-04-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural insights into catalytic mechanism and product delivery of cyanobacterial acyl-acyl carrier protein reductase. Nat Commun, 11, 2020
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6W66
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![BU of 6w66 by Molmil](/molmil-images/mine/6w66) | The structure of the F64A, S172A mutant Keap1-BTB domain in complex with SKP1-FBXL17 | 分子名称: | F-box/LRR-repeat protein 17, Kelch-like ECH-associated protein 1, S-phase kinase-associated protein 1 | 著者 | Mena, E.L, Gee, C.L, Kuriyan, J, Rape, M. | 登録日 | 2020-03-16 | 公開日 | 2020-08-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | 主引用文献 | Structural basis for dimerization quality control. Nature, 586, 2020
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6JZI
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![BU of 6jzi by Molmil](/molmil-images/mine/6jzi) | Structure of hen egg-white lysozyme obtained from SFX experiments under atmospheric pressure | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | 著者 | Nango, E, Sugahara, M, Nakane, T, Tanaka, T, Iwata, S. | 登録日 | 2019-05-02 | 公開日 | 2019-10-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | High-viscosity sample-injection device for serial femtosecond crystallography at atmospheric pressure. J.Appl.Crystallogr., 52, 2019
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7V35
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![BU of 7v35 by Molmil](/molmil-images/mine/7v35) | Cryo-EM structure of the GIPR/GLP-1R/GCGR triagonist peptide 20-bound human GCGR-Gs complex | 分子名称: | Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhao, F.h, Zhou, Q.T, Cong, Z.T, Hang, K.N, Zou, X.Y, Zhang, C, Chen, Y, Dai, A.T, Liang, A.Y, Ming, Q.Q, Wang, M, Chen, L.N, Xu, P.Y, Chang, R.L, Feng, W.B, Xia, T, Zhang, Y, Wu, B.L, Yang, D.H, Zhao, L.H, Xu, H.E, Wang, M.W. | 登録日 | 2021-08-10 | 公開日 | 2022-03-02 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors. Nat Commun, 13, 2022
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