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PDB: 37 件

4HRF
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Atomic structure of DUSP26
分子名称: Dual specificity protein phosphatase 26
著者Lokareddy, R.K, Bhardwaj, A, Cingolani, G.
登録日2012-10-27
公開日2013-01-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Atomic structure of dual-specificity phosphatase 26, a novel p53 phosphatase.
Biochemistry, 52, 2013
7UXE
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Pseudomonas phage E217 small terminase (TerS)
分子名称: Small terminase
著者Lokareddy, R.K, Hou, C.-F.D, Doll, S.G, Li, F, Gillilan, R, Forti, F, Briani, F, Cingolani, G.
登録日2022-05-05
公開日2022-09-28
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Terminase Subunits from the Pseudomonas-Phage E217.
J.Mol.Biol., 434, 2022
4XZR
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Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of INM protein Heh1
分子名称: Importin subunit alpha, Inner nuclear membrane protein SRC1
著者Lokareddy, R.K, Cingolani, G.
登録日2015-02-04
公開日2015-06-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2.
Structure, 23, 2015
4PVZ
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Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of INM protein Heh2
分子名称: Importin subunit alpha, Inner nuclear membrane protein HEH2
著者Lokareddy, R.K, Hapsari, A.R, van Rheenen, M, Bhardwaj, A, Veenhoff, L.M, Cingolani, C.
登録日2014-03-18
公開日2015-08-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2.
Structure, 23, 2015
5JJ3
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Refined Structure of the Mature Virion Conformation of P22 Portal Protein
分子名称: Portal protein
著者Lokareddy, R.K, Sankhala, R.S, Cingolani, G.
登録日2016-04-22
公開日2017-02-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (7 Å)
主引用文献Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation.
Nat Commun, 8, 2017
5JJ1
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Structure of the Immature Procapsid Conformation of P22 Portal Protein
分子名称: Portal protein
著者Lokareddy, R.K, Cingolani, G.
登録日2016-04-22
公開日2017-02-08
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation.
Nat Commun, 8, 2017
4YI0
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Structure of mouse importin a1 bound to Pom121NLS
分子名称: Importin subunit alpha-1, Nuclear envelope pore membrane protein POM 121
著者Lokareddy, R.K, Cingolani, G.
登録日2015-02-27
公開日2016-01-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.806 Å)
主引用文献Mammalian Pom121 and yeast Heh2 share IBB-like NLSs that support targeting to the inner nuclear membrane
To Be Published
3GZ2
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Crystal structure of IpgC in complex with an IpaB peptide
分子名称: Chaperone protein ipgC, GLYCEROL, IMIDAZOLE, ...
著者Lokareddy, R.K, Lunelli, M, Kolbe, M.
登録日2009-04-06
公開日2010-04-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Combination of two separate binding domains defines stoichiometry between type III secretion system chaperone IpgC and translocator protein IpaB
J.Biol.Chem., 285, 2010
8DKR
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Pseudomonas-phage E217 TerL nuclease domain
分子名称: Large terminase protein, MAGNESIUM ION
著者Cingolani, G, Lokareddy, R, Hou, D.
登録日2022-07-06
公開日2022-09-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Terminase Subunits from the Pseudomonas-Phage E217.
J.Mol.Biol., 434, 2022
7N9H
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Structure of the mammalian importin a1 bound to the TDP-43 NLS
分子名称: Importin subunit alpha-1, TAR DNA-binding protein 43
著者Doll, S.G, Lokareddy, R.K, Cingolani, G.
登録日2021-06-17
公開日2022-06-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Recognition of the TDP-43 nuclear localization signal by importin alpha 1/ beta.
Cell Rep, 39, 2022
6XMI
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Structure of Fab4 bound to P22 TerL(1-33)
分子名称: Fab Heavy chain, Fab Light chain, Terminase, ...
著者Cingolani, G, Lokareddy, R, Ko, Y.
登録日2020-06-30
公開日2020-08-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Recognition of an alpha-helical hairpin in P22 large terminase by a synthetic antibody fragment.
Acta Crystallogr D Struct Biol, 76, 2020
6RGV
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Truncated FljB phase 2 flagellin
分子名称: Flagellin
著者Lunelli, M, Lokareddy, R.K, Kolbe, M.
登録日2019-04-17
公開日2020-03-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion.
Nat Commun, 11, 2020
6E3B
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BU of 6e3b by Molmil
STRUCTURE OF Siw14 CATALYTIC CORE
分子名称: SULFATE ION, Tyrosine-protein phosphatase SIW14
著者Florio, T, Lokareddy, R, Cingolani, G.
登録日2018-07-13
公開日2019-02-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular Architecture of the Inositol Phosphatase Siw14.
Biochemistry, 58, 2019
6VI1
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Structure of Fab4 bound to P22 TerL(1-33)
分子名称: Synthetic Fab4 heavy chain, Synthetic Fab4 light chain, Terminase, ...
著者Cingolani, G, Lokareddy, R, Ko, Y.
登録日2020-01-11
公開日2020-09-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Recognition of an alpha-helical hairpin in P22 large terminase by a synthetic antibody fragment.
Acta Crystallogr D Struct Biol, 76, 2020
6W7T
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BU of 6w7t by Molmil
Structure of PaP3 small terminase
分子名称: small terminase subunit
著者Cingolani, G, Lokareddy, R.
登録日2020-03-19
公開日2020-11-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Biophysical analysis of Pseudomonas-phage PaP3 small terminase suggests a mechanism for sequence-specific DNA-binding by lateral interdigitation.
Nucleic Acids Res., 48, 2020
4NYH
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BU of 4nyh by Molmil
Orthorhombic crystal form of pir1 dual specificity phosphatase core
分子名称: CHLORIDE ION, PHOSPHATE ION, RNA/RNP complex-1-interacting phosphatase
著者Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
登録日2013-12-10
公開日2014-01-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase.
Biochemistry, 53, 2014
5HUY
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BU of 5huy by Molmil
Structure of HCMV Small Terminase NLS bound to importin alpha
分子名称: HCMV small terminase, Importin subunit alpha-1
著者Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
登録日2016-01-28
公開日2016-03-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.979 Å)
主引用文献Divergent Evolution of Nuclear Localization Signal Sequences in Herpesvirus Terminase Subunits.
J.Biol.Chem., 291, 2016
5HUW
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Structure of HSV-1 Large Terminase NLS bound to importin alpha
分子名称: HSV1 large terminase NLS, Importin subunit alpha-1
著者Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
登録日2016-01-27
公開日2016-03-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Divergent Evolution of Nuclear Localization Signal Sequences in Herpesvirus Terminase Subunits.
J.Biol.Chem., 291, 2016
6VI2
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BU of 6vi2 by Molmil
Structure of the unaligned Fab4
分子名称: FAB4 heavy chain, FAB4 light chain
著者Cingolani, G, Lokareddy, R, Ko, Y.
登録日2020-01-11
公開日2020-09-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Recognition of an alpha-helical hairpin in P22 large terminase by a synthetic antibody fragment.
Acta Crystallogr D Struct Biol, 76, 2020
4MBB
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Cubic crystal form of PIR1 dual specificity phosphatase core
分子名称: CHLORIDE ION, PHOSPHATE ION, RNA/RNP complex-1-interacting phosphatase
著者Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
登録日2013-08-19
公開日2013-12-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.849 Å)
主引用文献Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase.
Biochemistry, 53, 2014
4QLP
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BU of 4qlp by Molmil
Atomic structure of tuberculosis necrotizing toxin (TNT) complexed with its immunity factor IFT
分子名称: Alanine and proline rich protein, tuberculosis necrotizing toxin (TNT), immunity factor IFT
著者Cingolani, G, Lokareddy, R.K, Sun, J, Siroy, A, Speer, A, Doornbos, K.S, Niederweis, M.
登録日2014-06-12
公開日2015-07-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献The tuberculosis necrotizing toxin kills macrophages by hydrolyzing NAD.
Nat.Struct.Mol.Biol., 22, 2015
3GYZ
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BU of 3gyz by Molmil
Crystal structure of IpgC from Shigella flexneri
分子名称: Chaperone protein ipgC, GLYCEROL, SODIUM ION, ...
著者Lunelli, M, Lokareddy, R.K, Zychlinsky, A, Kolbe, M.
登録日2009-04-06
公開日2009-06-16
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献IpaB-IpgC interaction defines binding motif for type III secretion translocator
Proc.Natl.Acad.Sci.USA, 106, 2009
3GZ1
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Crystal structure of IpgC in complex with the chaperone binding region of IpaB
分子名称: Chaperone protein ipgC, GLYCEROL, Invasin ipaB
著者Lunelli, M, Lokareddy, R.K, Zychlinsky, A, Kolbe, M.
登録日2009-04-06
公開日2009-06-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献IpaB-IpgC interaction defines binding motif for type III secretion translocator
Proc.Natl.Acad.Sci.USA, 106, 2009
5T94
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Crystal structure of Kap60 bound to yeast RCC1 (Prp20)
分子名称: Guanine nucleotide exchange factor SRM1, Importin subunit alpha
著者Sankhala, R.S, Lokareddy, R.K, Pumroy, R.A, Cingolani, G.
登録日2016-09-09
公開日2017-09-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.631 Å)
主引用文献Three-dimensional context rather than NLS amino acid sequence determines importin alpha subtype specificity for RCC1.
Nat Commun, 8, 2017
5TBK
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Crystal structure of human importin a3 bound to RCC1
分子名称: Importin subunit alpha-3, Regulator of chromosome condensation
著者Sankhala, R.S, Lokareddy, R.K, Pumroy, R.A, Cingolani, G.
登録日2016-09-12
公開日2017-09-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Three-dimensional context rather than NLS amino acid sequence determines importin alpha subtype specificity for RCC1.
Nat Commun, 8, 2017

 

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