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PDB: 37 results
5TBK
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BU of 5tbk by Molmil
Crystal structure of human importin a3 bound to RCC1
Descriptor: Importin subunit alpha-3, Regulator of chromosome condensation
Authors:Sankhala, R.S, Lokareddy, R.K, Pumroy, R.A, Cingolani, G.
Deposit date:2016-09-12
Release date:2017-09-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Three-dimensional context rather than NLS amino acid sequence determines importin alpha subtype specificity for RCC1.
Nat Commun, 8, 2017
3GYZ
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BU of 3gyz by Molmil
Crystal structure of IpgC from Shigella flexneri
Descriptor: Chaperone protein ipgC, GLYCEROL, SODIUM ION, ...
Authors:Lunelli, M, Lokareddy, R.K, Zychlinsky, A, Kolbe, M.
Deposit date:2009-04-06
Release date:2009-06-16
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:IpaB-IpgC interaction defines binding motif for type III secretion translocator
Proc.Natl.Acad.Sci.USA, 106, 2009
5HUY
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BU of 5huy by Molmil
Structure of HCMV Small Terminase NLS bound to importin alpha
Descriptor: HCMV small terminase, Importin subunit alpha-1
Authors:Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
Deposit date:2016-01-28
Release date:2016-03-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.979 Å)
Cite:Divergent Evolution of Nuclear Localization Signal Sequences in Herpesvirus Terminase Subunits.
J.Biol.Chem., 291, 2016
5HUW
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BU of 5huw by Molmil
Structure of HSV-1 Large Terminase NLS bound to importin alpha
Descriptor: HSV1 large terminase NLS, Importin subunit alpha-1
Authors:Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
Deposit date:2016-01-27
Release date:2016-03-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Divergent Evolution of Nuclear Localization Signal Sequences in Herpesvirus Terminase Subunits.
J.Biol.Chem., 291, 2016
5V5P
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BU of 5v5p by Molmil
Structure of NLS2R of influenza A virus nucleoprotein bound to importin alpha
Descriptor: Importin subunit alpha-1, Nucleoprotein
Authors:Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
Deposit date:2017-03-14
Release date:2018-03-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Synergy of two low-affinity NLSs determines the high avidity of influenza A virus nucleoprotein NP for human importin alpha isoforms.
Sci Rep, 7, 2017
7LFC
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BU of 7lfc by Molmil
Structure of importin a3 bound to p50 NLS
Descriptor: Importin subunit alpha-3, Nuclear factor NF-kappa-B p105 subunit
Authors:Florio, T.J, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-01-16
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
7LF4
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BU of 7lf4 by Molmil
Structure of importin a3 bound to the p50- and p65-NLSs
Descriptor: Importin subunit alpha-3, Nuclear factor NF-kappa-B p105 subunit, Transcription factor p65
Authors:Florio, T.J, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-01-15
Release date:2022-01-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
7LET
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BU of 7let by Molmil
Structure of importin a2 bound to the p50- and p65-NLSs
Descriptor: Importin subunit alpha-1, Nuclear factor NF-kappa-B p105 subunit, Transcription factor p65
Authors:Florio, T.J, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-01-15
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
7LEU
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BU of 7leu by Molmil
Structure of importin a2 bound to p65-NLS
Descriptor: Importin subunit alpha-1, Transcription factor p65
Authors:Florio, T.J, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-01-15
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
7LEQ
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BU of 7leq by Molmil
Structure of importin a2 bound to p50 NLS
Descriptor: Importin subunit alpha-1, Nuclear factor NF-kappa-B p105 subunit
Authors:Florio, T.J, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-01-14
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
7N9H
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BU of 7n9h by Molmil
Structure of the mammalian importin a1 bound to the TDP-43 NLS
Descriptor: Importin subunit alpha-1, TAR DNA-binding protein 43
Authors:Doll, S.G, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-06-17
Release date:2022-06-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Recognition of the TDP-43 nuclear localization signal by importin alpha 1/ beta.
Cell Rep, 39, 2022
4QLP
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BU of 4qlp by Molmil
Atomic structure of tuberculosis necrotizing toxin (TNT) complexed with its immunity factor IFT
Descriptor: Alanine and proline rich protein, tuberculosis necrotizing toxin (TNT), immunity factor IFT
Authors:Cingolani, G, Lokareddy, R.K, Sun, J, Siroy, A, Speer, A, Doornbos, K.S, Niederweis, M.
Deposit date:2014-06-12
Release date:2015-07-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The tuberculosis necrotizing toxin kills macrophages by hydrolyzing NAD.
Nat.Struct.Mol.Biol., 22, 2015
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