4ACR
 
 | | Crystal structure of N-glycosylated, C-terminally truncated human glypican-1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYPICAN-1 | | 著者 | Svensson, G, Awad, W, Mani, K, Logan, D.T. | | 登録日 | 2011-12-17 | | 公開日 | 2012-02-22 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Crystal Structure of N-Glycosylated Human Glypican-1 Core Protein: Structure of Two Loops Evolutionarily Conserved in Vertebrate Glypican-1.
J.Biol.Chem., 287, 2012
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5EHB
 | | A de novo designed hexameric coiled-coil peptide with iodotyrosine | | 分子名称: | pHiosYI | | 著者 | Lizatovic, R, Aurelius, O, Stenstrom, O, Drakenberg, T, Akke, M, Logan, D.T, Andre, I. | | 登録日 | 2015-10-28 | | 公開日 | 2016-06-15 | | 最終更新日 | 2018-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | | 主引用文献 | A De Novo Designed Coiled-Coil Peptide with a Reversible pH-Induced Oligomerization Switch.
Structure, 24, 2016
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7R1O
 | | p62-ZZ domain of the human sequestosome in complex with dusquetide | | 分子名称: | Dusquetide, Sequestosome-1, ZINC ION | | 著者 | Hakansson, M, Hansson, M, Logan, D.T, Rozek, A, Donini, O. | | 登録日 | 2022-02-03 | | 公開日 | 2022-05-18 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | | 主引用文献 | Dusquetide modulates innate immune response through binding to p62.
Structure, 30, 2022
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3HFF
 | | Monomeric human Cu,Zn Superoxide dismutase without Zn ligands | | 分子名称: | Superoxide dismutase [Cu-Zn], ZINC ION | | 著者 | Saraboji, K, Nordlund, A, Leinartait, L, Oliveberg, M, Logan, D.T. | | 登録日 | 2009-05-11 | | 公開日 | 2009-06-16 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Functional features cause misfolding of the ALS-provoking enzyme SOD1.
Proc.Natl.Acad.Sci.USA, 106, 2009
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7ZXK
 | | Human IL-27 in complex with neutralizing SRF388 FAb fragment | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 subunit alpha, Interleukin-27 subunit beta, ... | | 著者 | Bloch, Y, Skladanowska, K, Strand, J, Welin, M, Logan, D, Hill, J, Savvides, S.N. | | 登録日 | 2022-05-21 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis of activation and antagonism of receptor signaling mediated by interleukin-27.
Cell Rep, 41, 2022
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1TDQ
 | | Structural basis for the interactions between tenascins and the C-type lectin domains from lecticans: evidence for a cross-linking role for tenascins | | 分子名称: | Aggrecan core protein, CALCIUM ION, Tenascin-R | | 著者 | Lundell, A, Olin, A.I, Moergelin, M, al-Karadaghi, S, Aspberg, A, Logan, D.T. | | 登録日 | 2004-05-24 | | 公開日 | 2004-08-31 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis for interactions between tenascins and lectican C-type lectin domains: evidence for a crosslinking role for tenascins
Structure, 12, 2004
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5J07
 | | Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P1/2 | | 分子名称: | Superoxide dismutase [Cu-Zn],Superoxide dismutase [Cu-Zn],Superoxide dismutase [Cu-Zn],Superoxide dismutase [Cu-Zn] | | 著者 | Wang, H, Lang, L, Logan, D, Danielsson, J, Oliveberg, M. | | 登録日 | 2016-03-27 | | 公開日 | 2017-02-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Tricking a Protein To Swap Strands.
J. Am. Chem. Soc., 138, 2016
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5J0C
 | | Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P2/3 | | 分子名称: | Superoxide dismutase [Cu-Zn],Superoxide dismutase [Cu-Zn],OXIDOREDUCTASE,Superoxide dismutase [Cu-Zn] | | 著者 | Wang, H, Lang, L, Logan, D, Danielsson, J, Oliveberg, M. | | 登録日 | 2016-03-28 | | 公開日 | 2017-02-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Tricking a Protein To Swap Strands.
J. Am. Chem. Soc., 138, 2016
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5J0G
 | | Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P7/8 | | 分子名称: | OXIDOREDUCTASE,Superoxide dismutase [Cu-Zn] | | 著者 | Wang, H, Lang, L, Logan, D, Danielsson, J, Oliveberg, M. | | 登録日 | 2016-03-28 | | 公開日 | 2017-02-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Tricking a Protein To Swap Strands.
J. Am. Chem. Soc., 138, 2016
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7OS7
 | | Circular permutant of ribosomal protein S6, swap helix 2, L75A, A92K mutant | | 分子名称: | 30S ribosomal protein S6,30S ribosomal protein S6 | | 著者 | Wang, H, Logan, D.T, Oliveberg, M. | | 登録日 | 2021-06-08 | | 公開日 | 2022-06-22 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Circular permutant of ribosomal protein S6, swap helix 2, L75A, A92K mutant
To Be Published
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3ZSK
 | | Crystal structure of Human Galectin-3 CRD with glycerol bound at 0.90 angstrom resolution | | 分子名称: | GALECTIN-3, GLYCEROL | | 著者 | Saraboji, K, Hakansson, M, Diehl, C, Nilsson, U.J, Leffler, H, Akke, M, Logan, D.T. | | 登録日 | 2011-06-28 | | 公開日 | 2011-12-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (0.9 Å) | | 主引用文献 | The Carbohydrate-Binding Site in Galectin-3 is Pre-Organized to Recognize a Sugar-Like Framework of Oxygens: Ultra-High Resolution Structures and Water Dynamics.
Biochemistry, 51, 2012
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2BV3
 | | Crystal structure of a mutant elongation factor G trapped with a GTP analogue | | 分子名称: | ELONGATION FACTOR G, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | | 著者 | Hansson, S, Singh, R, Gudkov, A.T, Liljas, A, Logan, D.T. | | 登録日 | 2005-06-22 | | 公開日 | 2005-08-10 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structure of a Mutant Elongation Factor G Trapped with a GTP Analogue.
FEBS Lett., 579, 2005
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5OAX
 | | Galectin-3c in complex with thiogalactoside derivate | | 分子名称: | 5,6-bis(fluoranyl)-3-[[(2~{S},3~{R},4~{S},5~{S},6~{R})-2-[(2~{S},3~{R},4~{S},5~{R},6~{R})-4-[4-(3-fluorophenyl)-1,2,3-triazol-1-yl]-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]sulfanyl-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-4-yl]oxymethyl]chromen-2-one, Galectin-3 | | 著者 | Nilsson, U.J, Peterson, K, Hakansson, M, Logan, D.T. | | 登録日 | 2017-06-25 | | 公開日 | 2018-05-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity.
J. Med. Chem., 61, 2018
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7TPS
 | | Crystal structure of ALPN-202 (engineered CD80 vIgD) in complex with PD-L1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Demonte, D.W, Maurer, M.F, Akutsu, M, Kimbung, Y.R, Logan, D.T, Walse, B. | | 登録日 | 2022-01-26 | | 公開日 | 2022-03-16 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | The engineered CD80 variant fusion therapeutic davoceticept combines checkpoint antagonism with conditional CD28 costimulation for anti-tumor immunity.
Nat Commun, 13, 2022
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3O0N
 | | Thermotoga maritima Ribonucleotide Reductase, NrdJ, in complex with dTTP and Adenosylcobalamin | | 分子名称: | 5'-DEOXYADENOSINE, CHLORIDE ION, COBALAMIN, ... | | 著者 | Larsson, K.-M, Logan, D.T, Nordlund, P. | | 登録日 | 2010-07-19 | | 公開日 | 2010-07-28 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural Basis for Adenosylcobalamin Activation in AdoCbl-Dependent Ribonucleotide Reductases.
Acs Chem.Biol., 5, 2010
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5ODY
 | | Galectin-3C in complex with dithiogalactoside derivative | | 分子名称: | 5,6-bis(fluoranyl)-3-[[(2~{R},3~{S},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,5-bis(oxidanyl)-4-[4-[3,4,5-tris(fluoranyl)phenyl]-1,2,3-triazol-1-yl]oxan-2-yl]sulfanyl-3,5-bis(oxidanyl)oxan-4-yl]oxymethyl]chromen-2-one, Galectin-3 | | 著者 | Kumar, R, Peterson, K, Nilsson, U.J, Logan, D.T. | | 登録日 | 2017-07-07 | | 公開日 | 2018-05-23 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.149 Å) | | 主引用文献 | Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity.
J. Med. Chem., 61, 2018
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3O0Q
 | | Thermotoga maritima Ribonucleotide Reductase, NrdJ, in complex with dTTP, GDP and Adenosine | | 分子名称: | ADENOSINE, CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Larsson, K.-M, Logan, D.T, Nordlund, P. | | 登録日 | 2010-07-19 | | 公開日 | 2010-07-28 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Basis for Adenosylcobalamin Activation in AdoCbl-Dependent Ribonucleotide Reductases.
Acs Chem.Biol., 5, 2010
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3O0O
 | | Thermotoga maritima Ribonucleotide Reductase, NrdJ, in complex with dTTP, GDP and Adenosylcobalamin | | 分子名称: | 5'-DEOXYADENOSINE, COBALAMIN, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Larsson, K.-M, Logan, D.T, Nordlund, P. | | 登録日 | 2010-07-19 | | 公開日 | 2010-07-28 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Basis for Adenosylcobalamin Activation in AdoCbl-Dependent Ribonucleotide Reductases.
Acs Chem.Biol., 5, 2010
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5M8E
 | | Crystal structure of a GH43 arabonofuranosidase from Weissella sp. strain 142 | | 分子名称: | Alpha-N-arabinofuranosidase, CALCIUM ION, GLYCEROL, ... | | 著者 | Linares-Pasten, J, Logan, D.T, Nordberg Karlsson, E. | | 登録日 | 2016-10-28 | | 公開日 | 2017-05-10 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Three-dimensional structures and functional studies of two GH43 arabinofuranosidases from Weissella sp. strain 142 and Lactobacillus brevis.
FEBS J., 284, 2017
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8P23
 | | Cryo-EM structure of the anaerobic ribonucleotide reductase from Prevotella copri in its dimeric, ATP/CTP-bound state | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Anaerobic ribonucleoside-triphosphate reductase, CYTIDINE-5'-TRIPHOSPHATE, ... | | 著者 | Banerjee, I, Bimai, O, Sjoberg, B.M, Logan, D.T. | | 登録日 | 2023-05-14 | | 公開日 | 2023-08-30 | | 最終更新日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | | 主引用文献 | Nucleotide binding to the ATP-cone in anaerobic ribonucleotide reductases allosterically regulates activity by modulating substrate binding.
Elife, 12, 2024
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8P27
 | | Cryo-EM structure of the anaerobic ribonucleotide reductase from Prevotella copri in its dimeric, dATP-bound state | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Anaerobic ribonucleoside-triphosphate reductase, MAGNESIUM ION | | 著者 | Banerjee, I, Bimai, O, Sjoberg, B.M, Logan, D.T. | | 登録日 | 2023-05-15 | | 公開日 | 2023-08-30 | | 最終更新日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | | 主引用文献 | Nucleotide binding to the ATP-cone in anaerobic ribonucleotide reductases allosterically regulates activity by modulating substrate binding.
Elife, 12, 2024
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5LFN
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8PF9
 | | Galectin-3C in complex with a triazolesulfane derivative | | 分子名称: | (2~{R},3~{S},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,5-bis(oxidanyl)-4-[4-[oxidanyl(phenyl)-$l^{3}-sulfanyl]-1,2,3-triazol-1-yl]oxan-2-yl]sulfanyl-oxane-3,4,5-triol, Galectin-3, MAGNESIUM ION, ... | | 著者 | Kumar, R, Mahanti, M, Nilsson, U.J, Logan, D.T. | | 登録日 | 2023-06-15 | | 公開日 | 2023-11-08 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | | 主引用文献 | Ligand Sulfur Oxidation State Progressively Alters Galectin-3-Ligand Complex Conformations To Induce Affinity-Influencing Hydrogen Bonds.
J.Med.Chem., 66, 2023
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2VT3
 | | Structure and functional properties of the Bacillus subtilis transcriptional repressor Rex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, REDOX-SENSING TRANSCRIPTIONAL REPRESSOR REX | | 著者 | Wang, E, Bauer, M.C, Rogstam, A, Linse, S, Logan, D, von Wachenfeldt, C. | | 登録日 | 2008-05-08 | | 公開日 | 2008-09-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure and functional properties of the Bacillus subtilis transcriptional repressor Rex.
Mol. Microbiol., 69, 2008
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8P28
 | | Cryo-EM structure of the anaerobic ribonucleotide reductase from Prevotella copri in its tetrameric, dATP-bound state | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Anaerobic ribonucleoside-triphosphate reductase, MAGNESIUM ION | | 著者 | Banerjee, I, Bimai, O, Sjoberg, B.M, Logan, D.T. | | 登録日 | 2023-05-15 | | 公開日 | 2023-08-30 | | 最終更新日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | | 主引用文献 | Nucleotide binding to the ATP-cone in anaerobic ribonucleotide reductases allosterically regulates activity by modulating substrate binding.
Elife, 12, 2024
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