2GZ2
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![BU of 2gz2 by Molmil](/molmil-images/mine/2gz2) | Structure of Aspartate Semialdehyde Dehydrogenase (ASADH) from Streptococcus pneumoniae complexed with 2',5'-ADP | Descriptor: | ADENOSINE-2'-5'-DIPHOSPHATE, Aspartate beta-semialdehyde dehydrogenase | Authors: | Faehnle, C.R, Le Coq, J, Liu, X, Viola, R.E. | Deposit date: | 2006-05-10 | Release date: | 2006-08-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Examination of key intermediates in the catalytic cycle of aspartate-beta-semialdehyde dehydrogenase from a gram-positive infectious bacteria. J.Biol.Chem., 281, 2006
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2GYY
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![BU of 2gyy by Molmil](/molmil-images/mine/2gyy) | |
6JKM
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![BU of 6jkm by Molmil](/molmil-images/mine/6jkm) | Crystal structure of BubR1 kinase domain | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Lin, L, Ye, S, Huang, Y, Liu, X, Zhang, R, Yao, X. | Deposit date: | 2019-03-01 | Release date: | 2019-06-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules. Cell Res., 29, 2019
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2L8S
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![BU of 2l8s by Molmil](/molmil-images/mine/2l8s) | |
4JFG
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![BU of 4jfg by Molmil](/molmil-images/mine/4jfg) | Crystal structure of sfGFP-66-HqAla | Descriptor: | CESIUM ION, Green fluorescent protein, quinolin-8-ol | Authors: | Wang, J, Liu, X, Li, J, Zhang, W, Hu, M, Zhou, J. | Deposit date: | 2013-02-28 | Release date: | 2013-10-02 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.001 Å) | Cite: | Significant expansion of the fluorescent protein chromophore through the genetic incorporation of a metal-chelating unnatural amino acid. Angew.Chem.Int.Ed.Engl., 52, 2013
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4GO1
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![BU of 4go1 by Molmil](/molmil-images/mine/4go1) | Crystal Structure of full length transcription repressor LsrR from E. coli. | Descriptor: | GLYCEROL, Transcriptional regulator LsrR | Authors: | Wu, M, Tao, Y, Liu, X, Zang, J. | Deposit date: | 2012-08-17 | Release date: | 2013-04-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Basis for Phosphorylated Autoinducer-2 Modulation of the Oligomerization State of the Global Transcription Regulator LsrR from Escherichia coli J.Biol.Chem., 288, 2013
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4K7E
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![BU of 4k7e by Molmil](/molmil-images/mine/4k7e) | Crystal structure of Junin virus nucleoprotein | Descriptor: | Nucleoprotein | Authors: | Zhang, Y.J, Li, L, Liu, X, Dong, S.S, Wang, W.M, Huo, T, Rao, Z.H, Yang, C. | Deposit date: | 2013-04-17 | Release date: | 2013-08-07 | Last modified: | 2013-10-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of Junin virus nucleoprotein J.Gen.Virol., 94, 2013
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4KP3
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![BU of 4kp3 by Molmil](/molmil-images/mine/4kp3) | Crystal Structure of MyoVa-GTD in Complex with Two Cargos | Descriptor: | Melanophilin, RILP-like protein 2, Unconventional myosin-Va | Authors: | Wei, Z, Liu, X, Yu, C, Zhang, M. | Deposit date: | 2013-05-13 | Release date: | 2013-07-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.405 Å) | Cite: | Structural basis of cargo recognitions for class V myosins Proc.Natl.Acad.Sci.USA, 110, 2013
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2MU3
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![BU of 2mu3 by Molmil](/molmil-images/mine/2mu3) | Spider wrapping silk fibre architecture arising from its modular soluble protein precursor | Descriptor: | Aciniform spidroin 1 | Authors: | Xu, L, Tremblay, M, Meng, Q, Liu, X, Rainey, J.K, Lefevre, T, Sarker, M, Orrell, K.E, Leclerc, J, Pezolet, M, Auger, M. | Deposit date: | 2014-09-03 | Release date: | 2015-07-08 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Spider wrapping silk fibre architecture arising from its modular soluble protein precursor. Sci Rep, 5, 2015
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6CAD
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![BU of 6cad by Molmil](/molmil-images/mine/6cad) | Crystal structure of RAF kinase domain bound to the inhibitor 2a | Descriptor: | 1-(propan-2-yl)-3-({3-[3-(trifluoromethyl)phenyl]isoquinolin-8-yl}ethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Serine/threonine-protein kinase B-raf | Authors: | Maisonneuve, P, Kurinov, I, Assadieskandar, A, Yu, C, Liu, X, Chen, Y.-C, Prakash, G.K.S, Zhang, C, SIcheri, F. | Deposit date: | 2018-01-30 | Release date: | 2018-02-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Effects of rigidity on the selectivity of protein kinase inhibitors. Eur J Med Chem, 146, 2018
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6C1G
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![BU of 6c1g by Molmil](/molmil-images/mine/6c1g) | High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin Force Sensing | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Mentes, A, Huehn, A, Liu, X, Zwolak, A, Dominguez, R, Shuman, H, Ostap, E.M, Sindelar, C.V. | Deposit date: | 2018-01-04 | Release date: | 2018-01-31 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6C1D
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![BU of 6c1d by Molmil](/molmil-images/mine/6c1d) | High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin Force Sensing | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Mentes, A, Huehn, A, Liu, X, Zwolak, A, Dominguez, R, Shuman, H, Ostap, E.M, Sindelar, C.V. | Deposit date: | 2018-01-04 | Release date: | 2018-01-31 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6C1H
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![BU of 6c1h by Molmil](/molmil-images/mine/6c1h) | High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin Force Sensing | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Mentes, A, Huehn, A, Liu, X, Zwolak, A, Dominguez, R, Shuman, H, Ostap, E.M, Sindelar, C.V. | Deposit date: | 2018-01-04 | Release date: | 2018-01-31 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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8JWE
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![BU of 8jwe by Molmil](/molmil-images/mine/8jwe) | |
7BZH
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![BU of 7bzh by Molmil](/molmil-images/mine/7bzh) | |
8HD8
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![BU of 8hd8 by Molmil](/molmil-images/mine/8hd8) | Crystal structure of TMPRSS2 in complex with 212-148 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, CALCIUM ION, ... | Authors: | Wang, H, Liu, X, Sun, L, Yang, H. | Deposit date: | 2022-11-03 | Release date: | 2023-12-13 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry. Nat Commun, 14, 2023
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3RFU
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![BU of 3rfu by Molmil](/molmil-images/mine/3rfu) | Crystal structure of a copper-transporting PIB-type ATPase | Descriptor: | Copper efflux ATPase, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Gourdon, P, Liu, X, Skjorringe, T, Morth, J.P, Birk Moller, L, Panyella Pedersen, B, Nissen, P. | Deposit date: | 2011-04-07 | Release date: | 2011-06-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure of a copper-transporting PIB-type ATPase. Nature, 475, 2011
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5ZHP
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![BU of 5zhp by Molmil](/molmil-images/mine/5zhp) | M3 muscarinic acetylcholine receptor in complex with a selective antagonist | Descriptor: | (1R,2R,4S,5S,7s)-7-({[4-fluoro-2-(thiophen-2-yl)phenyl]carbamoyl}oxy)-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.0~2,4~]nonan-9-ium, CITRIC ACID, HEXAETHYLENE GLYCOL, ... | Authors: | Liu, H, Hofmann, J, Fish, I, Schaake, B, Eitel, K, Bartuschat, A, Kaindl, J, Rampp, H, Banerjee, A, Hubner, H, Clark, M.J, Vincent, S.G, Fisher, J, Heinrich, M, Hirata, K, Liu, X, Sunahara, R.K, Shoichet, B.K, Kobilka, B.K, Gmeiner, P. | Deposit date: | 2018-03-13 | Release date: | 2018-11-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure-guided development of selective M3 muscarinic acetylcholine receptor antagonists Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6A6O
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![BU of 6a6o by Molmil](/molmil-images/mine/6a6o) | Crystal structure of acetyl ester-xyloside bifunctional hydrolase from Caldicellulosiruptor lactoaceticus | Descriptor: | Esterase/lipase-like protein | Authors: | Cao, H, Huang, Y, Sun, L.C, Liu, X, Liu, T.F, Wang, F.Z, Xin, F.J. | Deposit date: | 2018-06-28 | Release date: | 2019-06-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Insights into the Dual-Substrate Recognition and Catalytic Mechanisms of a Bifunctional Acetyl Ester-Xyloside Hydrolase from Caldicellulosiruptor lactoaceticus. Acs Catalysis, 9, 2019
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6IY2
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![BU of 6iy2 by Molmil](/molmil-images/mine/6iy2) | Structure of Snf2-MMTV-A nucleosome complex at shl2 in ADP state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA (147-MER), DNA (167-MER), ... | Authors: | Li, M, Xia, X, Liu, X, Li, X, Chen, Z. | Deposit date: | 2018-12-12 | Release date: | 2019-04-03 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Mechanism of DNA translocation underlying chromatin remodelling by Snf2. Nature, 567, 2019
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5Z3O
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![BU of 5z3o by Molmil](/molmil-images/mine/5z3o) | Structure of Snf2-nucleosome complex in ADP state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA (167-MER), Histone H2A, ... | Authors: | Li, M, Xia, X, Liu, X, Li, X, Chen, Z. | Deposit date: | 2018-01-08 | Release date: | 2019-04-03 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.62 Å) | Cite: | Mechanism of DNA translocation underlying chromatin remodelling by Snf2. Nature, 567, 2019
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5Z3V
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![BU of 5z3v by Molmil](/molmil-images/mine/5z3v) | Structure of Snf2-nucleosome complex at shl-2 in ADP BeFx state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (167-MER), ... | Authors: | Li, M, Xia, X, Liu, X, Li, X, Chen, Z. | Deposit date: | 2018-01-08 | Release date: | 2019-05-22 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.22 Å) | Cite: | Mechanism of DNA translocation underlying chromatin remodelling by Snf2. Nature, 567, 2019
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5Z3U
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![BU of 5z3u by Molmil](/molmil-images/mine/5z3u) | Structure of Snf2-nucleosome complex at shl2 in ADP BeFx state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (167-MER), ... | Authors: | Li, M, Xia, X, Liu, X, Li, X, Chen, Z. | Deposit date: | 2018-01-08 | Release date: | 2019-05-22 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.31 Å) | Cite: | Mechanism of DNA translocation underlying chromatin remodelling by Snf2. Nature, 567, 2019
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5Z3L
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![BU of 5z3l by Molmil](/molmil-images/mine/5z3l) | Structure of Snf2-nucleosome complex in apo state | Descriptor: | DNA (167-MER), Histone H2A, Histone H2B 1.1, ... | Authors: | Li, M, Xia, X, Liu, X, Li, X, Chen, Z. | Deposit date: | 2018-01-08 | Release date: | 2019-04-03 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.31 Å) | Cite: | Mechanism of DNA translocation underlying chromatin remodelling by Snf2. Nature, 567, 2019
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5X0X
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![BU of 5x0x by Molmil](/molmil-images/mine/5x0x) | Complex of Snf2-Nucleosome complex with Snf2 bound to position +6 of the nucleosome | Descriptor: | DNA (167-MER), Histone H2A, Histone H2B 1.1, ... | Authors: | Li, M, Liu, X, Xia, X, Chen, Z, Li, X. | Deposit date: | 2017-01-23 | Release date: | 2017-04-19 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.97 Å) | Cite: | Mechanism of chromatin remodelling revealed by the Snf2-nucleosome structure. Nature, 544, 2017
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