8IWN
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![BU of 8iwn by Molmil](/molmil-images/mine/8iwn) | ABCG25 EQ mutant in ATP-bound state | 分子名称: | ABC transporter G family member 25, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION | 著者 | Sun, L, Liu, X, Ying, W, Liao, L, Wei, H. | 登録日 | 2023-03-30 | 公開日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | ABCG25 EQ mutant in ATP-bound state To Be Published
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8IWK
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![BU of 8iwk by Molmil](/molmil-images/mine/8iwk) | ABCG25 Wild Type purified with DDM plus CHS in ABA-bound state | 分子名称: | (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, ABC transporter G family member 25 | 著者 | Sun, L, Liu, X, Ying, W, Liao, L, Wei, H. | 登録日 | 2023-03-30 | 公開日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | ABCG25 Wild Type purified with DDM plus CHS in ABA-bound state To Be Published
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8IWJ
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8J2G
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![BU of 8j2g by Molmil](/molmil-images/mine/8j2g) | |
8JH5
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8ILV
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![BU of 8ilv by Molmil](/molmil-images/mine/8ilv) | Cryo-EM structure of PI3Kalpha in complex with compound 18 | 分子名称: | N-[(2R)-1-(ethylamino)-1-oxidanylidene-3-[3-(2-quinoxalin-6-ylethynyl)phenyl]propan-2-yl]-2,3-dimethyl-quinoxaline-6-carboxamide, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 著者 | Zhou, Q, Liu, X, Neri, D, Li, W, Favalli, N, Bassi, G, Yang, S, Yang, D, Vogt, P.K, Wang, M.-W. | 登録日 | 2023-03-04 | 公開日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | 主引用文献 | Structural insights into the interaction of three Y-shaped ligands with PI3K alpha. Proc.Natl.Acad.Sci.USA, 120, 2023
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8ILS
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![BU of 8ils by Molmil](/molmil-images/mine/8ils) | Cryo-EM structure of PI3Kalpha in complex with compound 17 | 分子名称: | N-[(2R)-1-(ethylamino)-1-oxidanylidene-3-[4-(2-quinoxalin-6-ylethynyl)phenyl]propan-2-yl]-2,3-dimethyl-quinoxaline-6-carboxamide, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 著者 | Zhou, Q, Liu, X, Neri, D, Li, W, Favalli, N, Bassi, G, Yang, S, Yang, D, Vogt, P.K, Wang, M.-W. | 登録日 | 2023-03-04 | 公開日 | 2023-09-13 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into the interaction of three Y-shaped ligands with PI3K alpha. Proc.Natl.Acad.Sci.USA, 120, 2023
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3NYL
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![BU of 3nyl by Molmil](/molmil-images/mine/3nyl) | The X-ray structure of an antiparallel dimer of the human amyloid precursor protein E2 domain | 分子名称: | Amyloid beta (A4) protein (Peptidase nexin-II, Alzheimer disease), isoform CRA_b | 著者 | Ha, Y, Hu, J, Lee, S, Liu, X, Wang, Y. | 登録日 | 2010-07-15 | 公開日 | 2011-07-13 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The X-ray structure of an antiparallel dimer of the human amyloid precursor protein E2 domain. Mol.Cell, 15, 2004
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3TG3
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![BU of 3tg3 by Molmil](/molmil-images/mine/3tg3) | Crystal structure of the MAPK binding domain of MKP7 | 分子名称: | 1,2-ETHANEDIOL, Dual specificity protein phosphatase 16 | 著者 | Zhang, Y.Y, Liu, X, Wu, J.W, Wang, Z.X. | 登録日 | 2011-08-17 | 公開日 | 2012-03-14 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.675 Å) | 主引用文献 | A Distinct Interaction Mode Revealed by the Crystal Structure of the Kinase p38alpha with the MAPK Binding Domain of the Phosphatase MKP5. Sci.Signal., 4, 2011
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7VP8
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![BU of 7vp8 by Molmil](/molmil-images/mine/7vp8) | Crystal structure of ferritin from Ureaplasma urealyticum | 分子名称: | CHLORIDE ION, FE (III) ION, Ferritin-like diiron domain-containing protein | 著者 | Wang, W, Liu, X, Wang, Y, Fu, D, Wang, H. | 登録日 | 2021-10-15 | 公開日 | 2022-08-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.002 Å) | 主引用文献 | Distinct structural characteristics define a new subfamily of Mycoplasma ferritin Chin.Chem.Lett., 33, 2022
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7WC5
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![BU of 7wc5 by Molmil](/molmil-images/mine/7wc5) | Crystal structure of serotonin 2A receptor in complex with psilocin | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-[2-(dimethylamino)ethyl]-1~{H}-indol-4-ol, 5-hydroxytryptamine receptor 2A, ... | 著者 | Cao, D, Yu, J, Wang, H, Luo, Z, Liu, X, He, L, Qi, J, Fan, L, Tang, L, Chen, Z, Li, J, Cheng, J, Wang, S. | 登録日 | 2021-12-18 | 公開日 | 2022-01-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure-based discovery of nonhallucinogenic psychedelic analogs. Science, 375, 2022
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7WC6
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![BU of 7wc6 by Molmil](/molmil-images/mine/7wc6) | Crystal structure of serotonin 2A receptor in complex with LSD | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide, 5-hydroxytryptamine receptor 2A,Soluble cytochrome b562, ... | 著者 | Cao, D, Yu, J, Wang, H, Luo, Z, Liu, X, He, L, Qi, J, Fan, L, Tang, L, Chen, Z, Li, J, Cheng, J, Wang, S. | 登録日 | 2021-12-18 | 公開日 | 2022-01-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure-based discovery of nonhallucinogenic psychedelic analogs. Science, 375, 2022
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7WC9
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![BU of 7wc9 by Molmil](/molmil-images/mine/7wc9) | Crystal structure of serotonin 2A receptor in complex with non-hallucinogenic psychedelic analog | 分子名称: | (10~{R},15~{S})-12-[3-(2-methoxyphenyl)propyl]-4-methyl-1,4,12-triazatetracyclo[7.6.1.0^{5,16}.0^{10,15}]hexadeca-5(16),6,8-triene, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 5-hydroxytryptamine receptor 2A,5-hydroxytryptamine receptor 2A,Soluble cytochrome b562, ... | 著者 | Cao, D, Yu, J, Wang, H, Luo, Z, Liu, X, He, L, Qi, J, Fan, L, Tang, L, Chen, Z, Li, J, Cheng, J, Wang, S. | 登録日 | 2021-12-18 | 公開日 | 2022-01-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure-based discovery of nonhallucinogenic psychedelic analogs. Science, 375, 2022
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7WC7
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![BU of 7wc7 by Molmil](/molmil-images/mine/7wc7) | Crystal structure of serotonin 2A receptor in complex with lisuride | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 5-hydroxytryptamine receptor 2A,5-hydroxytryptamine receptor 2A,Soluble cytochrome b562, CHOLESTEROL, ... | 著者 | Cao, D, Yu, J, Wang, H, Luo, Z, Liu, X, He, L, Qi, J, Fan, L, Tang, L, Chen, Z, Li, J, Cheng, J, Wang, S. | 登録日 | 2021-12-18 | 公開日 | 2022-01-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure-based discovery of nonhallucinogenic psychedelic analogs. Science, 375, 2022
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7WC8
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![BU of 7wc8 by Molmil](/molmil-images/mine/7wc8) | Crystal structure of serotonin 2A receptor in complex with lumateperone | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1-(4-fluorophenyl)-4-[(10~{R},15~{S})-4-methyl-1,4,12-triazatetracyclo[7.6.1.0^{5,16}.0^{10,15}]hexadeca-5,7,9(16)-trien-12-yl]butan-1-one, 5-hydroxytryptamine receptor 2A,5-hydroxytryptamine receptor 2A,Soluble cytochrome b562, ... | 著者 | Cao, D, Yu, J, Wang, H, Luo, Z, Liu, X, He, L, Qi, J, Fan, L, Tang, L, Chen, Z, Li, J, Cheng, J, Wang, S. | 登録日 | 2021-12-18 | 公開日 | 2022-01-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Structure-based discovery of nonhallucinogenic psychedelic analogs. Science, 375, 2022
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7WC4
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![BU of 7wc4 by Molmil](/molmil-images/mine/7wc4) | Crystal structure of serotonin 2A receptor in complex with serotonin | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 5-hydroxytryptamine receptor 2A,5-hydroxytryptamine receptor 2A,5-hydroxytryptamine receptor 2A,Soluble cytochrome b562, CHOLESTEROL, ... | 著者 | Cao, D, Yu, J, Wang, H, Luo, Z, Liu, X, He, L, Qi, J, Fan, L, Tang, L, Chen, Z, Li, J, Cheng, J, Wang, S. | 登録日 | 2021-12-18 | 公開日 | 2022-01-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure-based discovery of nonhallucinogenic psychedelic analogs. Science, 375, 2022
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7WZB
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![BU of 7wzb by Molmil](/molmil-images/mine/7wzb) | lipopolysaccharide assembly protein LapB (open) | 分子名称: | Lipopolysaccharide assembly protein B, TRIETHYLENE GLYCOL, ZINC ION | 著者 | Yan, L, Dong, H, Li, H, Liu, X, Deng, Z, Dong, C, Zhang, Z. | 登録日 | 2022-02-17 | 公開日 | 2023-03-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | lipopolysaccharide assembly protein LapB (open) To Be Published
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7Y9V
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![BU of 7y9v by Molmil](/molmil-images/mine/7y9v) | Structure of the auxin exporter PIN1 in Arabidopsis thaliana in the IAA-bound state | 分子名称: | 1H-INDOL-3-YLACETIC ACID, Auxin efflux carrier component 1, nanobody | 著者 | Sun, L, Liu, X, Yang, Z, Xia, J. | 登録日 | 2022-06-26 | 公開日 | 2022-09-07 | 最終更新日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insights into auxin recognition and efflux by Arabidopsis PIN1. Nature, 609, 2022
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7Y9U
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![BU of 7y9u by Molmil](/molmil-images/mine/7y9u) | Structure of the auxin exporter PIN1 in Arabidopsis thaliana in the NPA-bound state | 分子名称: | 2-(naphthalen-1-ylcarbamoyl)benzoic acid, Auxin efflux carrier component 1, nanobody | 著者 | Sun, L, Liu, X, Yang, Z, Xia, J. | 登録日 | 2022-06-26 | 公開日 | 2022-09-07 | 最終更新日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insights into auxin recognition and efflux by Arabidopsis PIN1. Nature, 609, 2022
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7Y9T
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![BU of 7y9t by Molmil](/molmil-images/mine/7y9t) | Structure of the auxin exporter PIN1 in Arabidopsis thaliana in the apo state | 分子名称: | Auxin efflux carrier component 1, nanobody | 著者 | Sun, L, Liu, X, Yang, Z, Xia, J. | 登録日 | 2022-06-26 | 公開日 | 2022-09-07 | 最終更新日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into auxin recognition and efflux by Arabidopsis PIN1. Nature, 609, 2022
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7X4B
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![BU of 7x4b by Molmil](/molmil-images/mine/7x4b) | Crystal Structure of An Anti-CRISPR Protein | 分子名称: | Anti-CRISPR protein (AcrIIC1), SULFATE ION | 著者 | Hu, J, Zhang, S, Gao, J.Y, Liu, X, Liu, J. | 登録日 | 2022-03-02 | 公開日 | 2022-10-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | A redox switch regulates the assembly and anti-CRISPR activity of AcrIIC1. Nat Commun, 13, 2022
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