6JKN
 
 | | Crystal Structure of G-quadruplex Formed by Bromo-substituted Human Telomeric DNA | | Descriptor: | DNA (5'-D(*GP*GP*GP*TP*TP*AP*GP*(BGM)P*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*(BGM)P*G)-3'), POTASSIUM ION | | Authors: | Geng, Y, Cai, Q, Liu, C, Zhu, G. | | Deposit date: | 2019-03-01 | | Release date: | 2019-04-03 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.401 Å) | | Cite: | The crystal structure of an antiparallel chair-type G-quadruplex formed by Bromo-substituted human telomeric DNA.
Nucleic Acids Res., 47, 2019
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6JKZ
 | | Crystal structure of VvPlpA from Vibrio vulnificus | | Descriptor: | 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, CHLORIDE ION, Thermolabile hemolysin | | Authors: | Ma, Q, Wan, Y, Liu, C. | | Deposit date: | 2019-03-03 | | Release date: | 2019-05-15 | | Last modified: | 2019-08-14 | | Method: | X-RAY DIFFRACTION (1.397 Å) | | Cite: | Structural analysis of aVibriophospholipase reveals an unusual Ser-His-chloride catalytic triad.
J.Biol.Chem., 294, 2019
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6JL1
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6JL2
 | | Crystal structure of VvPlpA G389N from Vibrio vulnificus | | Descriptor: | 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, HEXAETHYLENE GLYCOL, Thermolabile hemolysin | | Authors: | Ma, Q, Wan, Y, Liu, C. | | Deposit date: | 2019-03-03 | | Release date: | 2019-05-15 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural analysis of aVibriophospholipase reveals an unusual Ser-His-chloride catalytic triad.
J.Biol.Chem., 294, 2019
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6KJ3
 | | 120kV MicroED structure of FUS (37-42) SYSGYS solved from merged datasets at 0.60 A | | Descriptor: | RNA-binding protein FUS | | Authors: | Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X. | | Deposit date: | 2019-07-20 | | Release date: | 2019-10-02 | | Last modified: | 2024-03-27 | | Method: | ELECTRON CRYSTALLOGRAPHY (0.6 Å) | | Cite: | Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules.
Anal.Chem., 91, 2019
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6K7S
 | | Crystal structure of thymidylate synthase from shrimp | | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, TOMUDEX, Thymidylate synthase | | Authors: | Ma, Q, Zang, K, Liu, C. | | Deposit date: | 2019-06-08 | | Release date: | 2020-06-10 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.56 Å) | | Cite: | Structural analysis of a shrimp thymidylate synthase reveals species-specific interactions with dUMP and raltitrexed.
J Oceanol Limnol, 38, 2020
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6K7Q
 | | Crystal structure of thymidylate synthase from shrimp | | Descriptor: | SULFATE ION, Thymidylate synthase | | Authors: | Ma, Q, Zang, K, Liu, C. | | Deposit date: | 2019-06-08 | | Release date: | 2020-06-10 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.27 Å) | | Cite: | Structural analysis of a shrimp thymidylate synthase reveals species-specific interactions with dUMP and raltitrexed.
J Oceanol Limnol, 38, 2020
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6K7R
 | | Crystal structure of thymidylate synthase from shrimp | | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Thymidylate synthase | | Authors: | Ma, Q, Zang, K, Liu, C. | | Deposit date: | 2019-06-08 | | Release date: | 2020-06-10 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | Structural analysis of a shrimp thymidylate synthase reveals species-specific interactions with dUMP and raltitrexed.
J Oceanol Limnol, 38, 2020
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6KJ4
 | | 120kV MicroED structure of FUS (37-42) SYSGYS solved from single crystal at 0.65 A | | Descriptor: | RNA-binding protein FUS | | Authors: | Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X. | | Deposit date: | 2019-07-20 | | Release date: | 2019-10-02 | | Last modified: | 2024-03-27 | | Method: | ELECTRON CRYSTALLOGRAPHY (0.65 Å) | | Cite: | Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules.
Anal.Chem., 91, 2019
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6KJ2
 | | 200kV MicroED structure of FUS (37-42) SYSGYS solved from single crystal at 0.67 A | | Descriptor: | RNA-binding protein FUS | | Authors: | Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X. | | Deposit date: | 2019-07-20 | | Release date: | 2019-10-02 | | Last modified: | 2024-03-27 | | Method: | ELECTRON CRYSTALLOGRAPHY (0.67 Å) | | Cite: | Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules.
Anal.Chem., 91, 2019
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7VQQ
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7VZF
 | | Cryo-EM structure of amyloid fibril formed by full-length human SOD1 | | Descriptor: | Superoxide dismutase [Cu-Zn] | | Authors: | Wang, L.Q, Ma, Y.Y, Yuan, H.Y, Zhao, K, Zhang, M.Y, Wang, Q, Huang, X, Xu, W.C, Chen, J, Li, D, Zhang, D.L, Zou, L.Y, Yin, P, Liu, C, Liang, Y. | | Deposit date: | 2021-11-16 | | Release date: | 2022-06-29 | | Last modified: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (2.95 Å) | | Cite: | Cryo-EM structure of an amyloid fibril formed by full-length human SOD1 reveals its conformational conversion.
Nat Commun, 13, 2022
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8HZC
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8HZB
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8HZS
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8J2D
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7V3P
 | | Cryo-EM structure of the IGF1R/insulin complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin A chain, Insulin B chain, ... | | Authors: | Zhang, J, Liu, C, Zhang, X, Wei, T, Wu, C. | | Deposit date: | 2021-08-11 | | Release date: | 2022-08-17 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cryo-EM structure of the IGF1R/insulin complex
To Be Published
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7DWV
 | | Cryo-EM structure of amyloid fibril formed by familial prion disease-related mutation E196K | | Descriptor: | Major prion protein | | Authors: | Wang, L.Q, Zhao, K, Yuan, H.Y, Li, X.N, Dang, H.B, Ma, Y.Y, Wang, Q, Wang, C, Sun, Y.P, Chen, J, Li, D, Zhang, D.L, Yin, P, Liu, C, Liang, Y. | | Deposit date: | 2021-01-18 | | Release date: | 2021-10-13 | | Method: | ELECTRON MICROSCOPY (3.07 Å) | | Cite: | Genetic prion disease-related mutation E196K displays a novel amyloid fibril structure revealed by cryo-EM.
Sci Adv, 7, 2021
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7V4B
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7V4C
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7V4A
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7V4D
 | | Heparin-remodelled alpha-synuclein fibrils | | Descriptor: | Alpha-synuclein | | Authors: | Tao, Y.Q, Sun, Y.P, Xia, W.C, Zhao, Q.Y, Liu, C, Li, D. | | Deposit date: | 2021-08-12 | | Release date: | 2022-08-17 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Heparin-remodelled alpha-synuclein fibrils
To Be Published
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7WIY
 | | Cryo-EM structure of human TPH2 tetramer | | Descriptor: | FE (III) ION, IMIDAZOLE, Tryptophan 5-hydroxylase 2 | | Authors: | Zhu, K.F, Liu, C, Zhang, H.W, Wang, D.P. | | Deposit date: | 2022-01-05 | | Release date: | 2022-10-05 | | Last modified: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (3.09 Å) | | Cite: | Cryo-EM Structure and Activator Screening of Human Tryptophan Hydroxylase 2.
Front Pharmacol, 13, 2022
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7WMM
 | | alpha-synuclein fibril-F0502B complex | | Descriptor: | 2-bromanyl-4-[(~{E})-2-[6-[2-(2-fluoranylethoxy)ethyl-methyl-amino]-5-methyl-1,3-benzothiazol-2-yl]ethenyl]phenol, Alpha-synuclein | | Authors: | Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D. | | Deposit date: | 2022-01-15 | | Release date: | 2023-01-18 | | Last modified: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | alpha-synuclein fibril-F0502B complex
To Be Published
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7E0F
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