1VCY
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![BU of 1vcy by Molmil](/molmil-images/mine/1vcy) | VVA2 isoform | 分子名称: | MALONATE ION, volvatoxin A2 | 著者 | Lin, S.-C, Lo, Y.-C, Lin, J.-Y, Liaw, Y.-C. | 登録日 | 2004-03-17 | 公開日 | 2004-10-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structures and electron micrographs of fungal volvatoxin A2 J.Mol.Biol., 343, 2004
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5VJH
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![BU of 5vjh by Molmil](/molmil-images/mine/5vjh) | Closed State CryoEM Reconstruction of Hsp104:ATPyS and FITC casein | 分子名称: | FITC casein, Heat shock protein 104, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | 著者 | Gates, S.N, Yokom, A.L, Lin, J.-B, Jackrel, M.E, Rizo, A.N, Kendsersky, N.M, Buell, C.E, Sweeny, E.A, Chuang, E, Torrente, M.P, Mack, K.L, Su, M, Shorter, J, Southworth, D.R. | 登録日 | 2017-04-19 | 公開日 | 2017-07-05 | 最終更新日 | 2017-08-02 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104. Science, 357, 2017
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3CDG
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![BU of 3cdg by Molmil](/molmil-images/mine/3cdg) | Human CD94/NKG2A in complex with HLA-E | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain E, ... | 著者 | Petrie, E.J, Clements, C.S, Lin, J, Sullivan, L.C, Johnson, D, Huyton, T, Heroux, A, Hoare, H.L, Beddoe, T, Reid, H.H, Wilce, M.C.J, Brooks, A.G, Rossjohn, J. | 登録日 | 2008-02-26 | 公開日 | 2008-04-22 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence J.Exp.Med., 205, 2008
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3BZE
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![BU of 3bze by Molmil](/molmil-images/mine/3bze) | The human non-classical major histocompatibility complex molecule HLA-E | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain E, ... | 著者 | Hoare, H.L, Sullivan, L.C, Ely, L.K, Beddoe, T, Henderson, K.N, Lin, J, Clements, C.S, Reid, H.H, Brooks, A.G, Rossjohn, J. | 登録日 | 2008-01-17 | 公開日 | 2008-04-29 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Subtle changes in peptide conformation profoundly affect recognition of the non-classical MHC class I molecule HLA-E by the CD94-NKG2 natural killer cell receptors J.Mol.Biol., 377, 2008
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8Y37
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![BU of 8y37 by Molmil](/molmil-images/mine/8y37) | Cryo-EM structure of Staphylococcus aureus (15B196) 50S ribosome in complex with MCX-190. | 分子名称: | 23S ribosomal RNA, 5S ribosomal RNA, 7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid, ... | 著者 | Li, Y, Lu, G, Li, J, Pei, X, Lin, J. | 登録日 | 2024-01-28 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.53 Å) | 主引用文献 | Synthetic macrolides overcoming MLS B K-resistant pathogens. Cell Discov, 10, 2024
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8Y39
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![BU of 8y39 by Molmil](/molmil-images/mine/8y39) | cryo-EM structure of Staphylococcus aureus(ATCC 29213) 70S ribosome in complex with MCX-190. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 5S ribosomal RNA, ... | 著者 | Li, Y, Lu, G, Li, J, Pei, X, Lin, J. | 登録日 | 2024-01-28 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Synthetic macrolides overcoming MLS B K-resistant pathogens. Cell Discov, 10, 2024
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8Y36
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![BU of 8y36 by Molmil](/molmil-images/mine/8y36) | cryo-EM structure of Staphylococcus aureus(ATCC 29213) 50S ribosome in complex with MCX-190. | 分子名称: | 23S ribosomal RNA, 5S ribosomal RNA, 7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid, ... | 著者 | Li, Y, Lu, G, Li, J, Pei, X, Lin, J. | 登録日 | 2024-01-28 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | 主引用文献 | Synthetic macrolides overcoming MLS B K-resistant pathogens. Cell Discov, 10, 2024
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8Y38
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![BU of 8y38 by Molmil](/molmil-images/mine/8y38) | Cryo-EM structure of Staphylococcus aureus 70S ribosome (strain 15B196) in complex with MCX-190. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 5S ribosomal RNA, ... | 著者 | Li, Y, Lu, G, Li, J, Pei, X, Lin, J. | 登録日 | 2024-01-28 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.58 Å) | 主引用文献 | Synthetic macrolides overcoming MLS B K-resistant pathogens. Cell Discov, 10, 2024
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5GIN
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![BU of 5gin by Molmil](/molmil-images/mine/5gin) | Crystal structure of box C/D RNP with 12 nt guide regions and 9 nt substrates | 分子名称: | 50S ribosomal protein L7Ae, C/D RNA, C/D box methylation guide ribonucleoprotein complex aNOP56 subunit, ... | 著者 | Yang, Z, Lin, J, Ye, K. | 登録日 | 2016-06-24 | 公開日 | 2016-09-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.308 Å) | 主引用文献 | Box C/D guide RNAs recognize a maximum of 10 nt of substrates Proc.Natl.Acad.Sci.USA, 113, 2016
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8W7H
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![BU of 8w7h by Molmil](/molmil-images/mine/8w7h) | Purine Nucleoside Phosphorylase in complex with MMV000848 | 分子名称: | (2R)-1-(9H-carbazol-9-yl)-3-(cyclopentylamino)propan-2-ol, 1,2-ETHANEDIOL, PHOSPHATE ION, ... | 著者 | Chung, Z, Lin, J.Q, Lescar, J. | 登録日 | 2023-08-30 | 公開日 | 2024-01-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Identification and structural validation of purine nucleoside phosphorylase from Plasmodium falciparum as a target of MMV000848. J.Biol.Chem., 300, 2023
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7CFM
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![BU of 7cfm by Molmil](/molmil-images/mine/7cfm) | Cryo-EM structure of the P395-bound GPBAR-Gs complex | 分子名称: | 2-(ethylamino)-6-[3-(4-propan-2-ylphenyl)propanoyl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide, CHOLESTEROL, G-protein coupled bile acid receptor 1, ... | 著者 | Yang, F, Mao, C, Guo, L, Lin, J, Ming, Q, Xiao, P, Wu, X, Shen, Q, Guo, S, Shen, D, Lu, R, Zhang, L, Huang, S, Ping, Y, Zhang, C, Ma, C, Zhang, K, Liang, X, Shen, Y, Nan, F, Yi, F, Luca, V, Zhou, J, Jiang, C, Sun, J, Xie, X, Yu, X, Zhang, Y. | 登録日 | 2020-06-27 | 公開日 | 2020-09-09 | 最終更新日 | 2020-12-02 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis of GPBAR activation and bile acid recognition. Nature, 587, 2020
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7CFN
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![BU of 7cfn by Molmil](/molmil-images/mine/7cfn) | Cryo-EM structure of the INT-777-bound GPBAR-Gs complex | 分子名称: | (2S,4R)-4-[(3R,5S,6R,7R,8R,9S,10S,12S,13R,14S,17R)-6-ethyl-10,13-dimethyl-3,7,12-tris(oxidanyl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-pentanoic acid, CHOLESTEROL, G-protein coupled bile acid receptor 1, ... | 著者 | Yang, F, Mao, C, Guo, L, Lin, J, Ming, Q, Xiao, P, Wu, X, Shen, Q, Guo, S, Shen, D, Lu, R, Zhang, L, Huang, S, Ping, Y, Zhang, C, Ma, C, Zhang, K, Liang, X, Shen, Y, Nan, F, Yi, F, Luca, V, Zhou, J, Jiang, C, Sun, J, Xie, X, Yu, X, Zhang, Y. | 登録日 | 2020-06-27 | 公開日 | 2020-09-09 | 最終更新日 | 2021-04-07 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis of GPBAR activation and bile acid recognition. Nature, 587, 2020
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4TY9
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![BU of 4ty9 by Molmil](/molmil-images/mine/4ty9) | An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline | 分子名称: | 5-(trifluoromethyl)pyridin-2-amine, Polyprotein | 著者 | Shui, W, Yang, C, Lin, J, Chen, X, Qin, S, Chen, S. | 登録日 | 2014-07-08 | 公開日 | 2015-05-06 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline Sci Rep, 5, 2015
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4TYA
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![BU of 4tya by Molmil](/molmil-images/mine/4tya) | An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline | 分子名称: | 4-(trifluoromethyl)benzoic acid, Polyprotein | 著者 | Shui, W, Yang, C, Lin, J, Chen, X, Qin, S, Chen, S. | 登録日 | 2014-07-08 | 公開日 | 2015-05-06 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | 主引用文献 | A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline Sci Rep, 5, 2015
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4TYB
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![BU of 4tyb by Molmil](/molmil-images/mine/4tyb) | An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline | 分子名称: | (2R)-morpholin-4-yl(phenyl)ethanenitrile, Polyprotein | 著者 | Shui, W, Yang, C, Lin, J, Chen, X, Qin, S, Chen, S. | 登録日 | 2014-07-08 | 公開日 | 2015-05-20 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.93 Å) | 主引用文献 | A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline Sci Rep, 5, 2015
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4TXS
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![BU of 4txs by Molmil](/molmil-images/mine/4txs) | An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline | 分子名称: | (4-hydroxyphenyl)acetonitrile, Polyprotein | 著者 | Shui, W, Yang, C, Lin, J, Chen, X, Qin, S, Chen, S. | 登録日 | 2014-07-07 | 公開日 | 2015-05-06 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline Sci Rep, 5, 2015
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4TY8
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![BU of 4ty8 by Molmil](/molmil-images/mine/4ty8) | An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline | 分子名称: | 6-methyl-2H-chromen-2-one, Polyprotein | 著者 | Shui, W, Yang, C, Lin, J, Chen, X, Qin, S, Chen, S. | 登録日 | 2014-07-08 | 公開日 | 2015-05-06 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline Sci Rep, 5, 2015
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4W2E
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![BU of 4w2e by Molmil](/molmil-images/mine/4w2e) | Crystal structure of Elongation Factor 4 (EF4/LepA) bound to the Thermus thermophilus 70S ribosome | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Gagnon, M.G, Lin, J, Steitz, T.A. | 登録日 | 2014-06-04 | 公開日 | 2014-10-01 | 最終更新日 | 2023-07-26 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of elongation factor 4 bound to a clockwise ratcheted ribosome. Science, 345, 2014
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8FZD
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![BU of 8fzd by Molmil](/molmil-images/mine/8fzd) | Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with apoRF3, RF1, P- and E-site tRNAPhe (Composite state I-B) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | 登録日 | 2023-01-28 | 公開日 | 2024-07-17 | 最終更新日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The ribosome termination complex remodels release factor RF3 and ejects GDP. Nat.Struct.Mol.Biol., 2024
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8FZE
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![BU of 8fze by Molmil](/molmil-images/mine/8fze) | Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with RF1, P- and E-site tRNAPhe (State I-A) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | 登録日 | 2023-01-28 | 公開日 | 2024-07-17 | 最終更新日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | The ribosome termination complex remodels release factor RF3 and ejects GDP. Nat.Struct.Mol.Biol., 2024
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8FZF
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![BU of 8fzf by Molmil](/molmil-images/mine/8fzf) | Cryo-EM structure of an E. coli rotated ribosome complex bound with RF3-ppGpp and p/E-tRNAPhe (Composite state I-C) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | 登録日 | 2023-01-28 | 公開日 | 2024-06-26 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The ribosome termination complex remodels release factor RF3 and ejects GDP. Nat.Struct.Mol.Biol., 2024
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8FZI
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![BU of 8fzi by Molmil](/molmil-images/mine/8fzi) | Cryo-EM structure of an E. coli rotated ribosome bound with RF3-GDPCP and p/E-tRNAPhe (Composite state II-B) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | 登録日 | 2023-01-28 | 公開日 | 2024-07-17 | 最終更新日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The ribosome termination complex remodels release factor RF3 and ejects GDP. Nat.Struct.Mol.Biol., 2024
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8FZH
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![BU of 8fzh by Molmil](/molmil-images/mine/8fzh) | Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with RF1, P- and E-site tRNAPhe (State II-D) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | 登録日 | 2023-01-28 | 公開日 | 2024-07-17 | 最終更新日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | The ribosome termination complex remodels release factor RF3 and ejects GDP. Nat.Struct.Mol.Biol., 2024
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8FZJ
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![BU of 8fzj by Molmil](/molmil-images/mine/8fzj) | Cryo-EM structure of an E. coli rotated ribosome bound with RF3-GDPCP and p/E-tRNAPhe (Composite state II-C) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | 登録日 | 2023-01-28 | 公開日 | 2024-07-17 | 最終更新日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | The ribosome termination complex remodels release factor RF3 and ejects GDP. Nat.Struct.Mol.Biol., 2024
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8FZG
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![BU of 8fzg by Molmil](/molmil-images/mine/8fzg) | Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with RF3-GDPCP, RF1, P- and E-site tRNAPhe (Composite state II-A) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | 登録日 | 2023-01-28 | 公開日 | 2024-07-17 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The ribosome termination complex remodels release factor RF3 and ejects GDP. Nat.Struct.Mol.Biol., 2024
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