7R32
 
 | | Carbon regulatory PII-like protein SbtB from Synechocystis sp. 6803, delta104 variant, in complex with ADP (co-crystal), tetragonal crystal form | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Membrane-associated protein slr1513 | | Authors: | Selim, K.A, Albrecht, R, Hartmann, M.D. | | Deposit date: | 2022-02-06 | | Release date: | 2023-02-15 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Carbon signaling protein SbtB possesses atypical redox-regulated apyrase activity to facilitate regulation of bicarbonate transporter SbtA.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
6GF3
 | | Tubulin-Jerantinine B acetate complex | | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | Authors: | Smedley, C.J, Stanley, P.A, Qazzaz, M.E, Prota, A.E, Olieric, N, Collins, H, Eastman, H, Barrow, A.S, Lim, K.-H, Kam, T.-S, Smith, B.J, Duivenvoorden, H.M, Parker, B.S, Bradshaw, T.D, Steinmetz, M.O, Moses, J.E. | | Deposit date: | 2018-04-29 | | Release date: | 2019-05-08 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Sustainable Syntheses of (-)-Jerantinines A & E and Structural Characterisation of the Jerantinine-Tubulin Complex at the Colchicine Binding Site.
Sci Rep, 8, 2018
|
|
4U5M
 | | Structure of a left-handed DNA G-quadruplex | | Descriptor: | DNA (28-MER), MAGNESIUM ION, POTASSIUM ION | | Authors: | Schmitt, E, Mechulam, Y, Phan, A.T, Brahim, H, Chung, W.J, Lim, K.W. | | Deposit date: | 2014-07-25 | | Release date: | 2015-02-25 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure of a left-handed DNA G-quadruplex.
Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
7VF1
 | |
6XBZ
 | | Structure of the human CDK-activating kinase | | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | | Authors: | Greber, B.J, Perez-Bertoldi, J.M, Lim, K, Iavarone, A.T, Toso, D.B, Nogales, E. | | Deposit date: | 2020-06-07 | | Release date: | 2020-09-09 | | Last modified: | 2020-09-30 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | The cryoelectron microscopy structure of the human CDK-activating kinase.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6XD3
 | | Structure of the human CAK in complex with THZ1 | | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | | Authors: | Greber, B.J, Perez-Bertoldi, J.M, Lim, K, Iavarone, A.T, Toso, D.B, Nogales, E. | | Deposit date: | 2020-06-09 | | Release date: | 2020-09-09 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | The cryoelectron microscopy structure of the human CDK-activating kinase.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
2GC8
 | | Structure of a Proline Sulfonamide Inhibitor Bound to HCV NS5b Polymerase | | Descriptor: | 1-[(2-AMINO-4-CHLORO-5-METHYLPHENYL)SULFONYL]-L-PROLINE, RNA-directed RNA polymerase | | Authors: | Gopalsamy, A, Chopra, R, Lim, K, Ciszewski, G, Shi, M, Curran, K.J, Sukits, S.F, Svenson, K, Bard, J, Ellingboe, J.W, Agarwal, A, Krishnamurthy, G, Howe, A.Y, Orlowski, M, Feld, B, O'connell, J, Mansour, T.S. | | Deposit date: | 2006-03-13 | | Release date: | 2006-06-13 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Discovery of Proline Sulfonamides as Potent and Selective Hepatitis C Virus NS5b Polymerase Inhibitors. Evidence for a New NS5b Polymerase Binding Site.
J.Med.Chem., 49, 2006
|
|
4JNJ
 | | Structure based engineering of streptavidin monomer with a reduced biotin dissociation rate | | Descriptor: | BIOTIN, Streptavidin/Rhizavidin Hybrid, ZINC ION | | Authors: | DeMonte, D, Drake, E.J, Hong Lim, K, Gulick, A.M, Park, S. | | Deposit date: | 2013-03-15 | | Release date: | 2013-05-29 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.902 Å) | | Cite: | Structure-based engineering of streptavidin monomer with a reduced biotin dissociation rate.
Proteins, 81, 2013
|
|
2KOW
 | |
2LE6
 | | Structure of a dimeric all-parallel-stranded G-quadruplex stacked via the 5'-to-5' interface | | Descriptor: | DNA (5'-D(*GP*IP*GP*TP*GP*GP*GP*TP*GP*GP*GP*TP*GP*GP*GP*T)-3') | | Authors: | Do, N.Q, Lim, K.W, Teo, M.H, Heddi, B, Phan, A.T. | | Deposit date: | 2011-06-10 | | Release date: | 2011-08-31 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Stacking of G-quadruplexes: NMR structure of a G-rich oligonucleotide with potential anti-HIV and anticancer activity
Nucleic Acids Res., 2011
|
|
2MS9
 | | Solution structure of a G-quadruplex | | Descriptor: | DNA (28-MER) | | Authors: | Chung, W.J, Heddi, B, Schmitt, E, Lim, K.W, Mechulam, Y, Phan, A.T. | | Deposit date: | 2014-07-25 | | Release date: | 2015-02-18 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structure of a left-handed DNA G-quadruplex
Proc.Natl.Acad.Sci.USA, 2015
|
|
7FHE
 | | Structure of prenyltransferase mutant Q295F from Streptomyces sp. (strain CL190) | | Descriptor: | Prenyltransferase | | Authors: | Xue, B, Lim, K.J.H, Hartono, Y.D, Go, M.D.K, Fan, H, Yew, W.S. | | Deposit date: | 2021-07-29 | | Release date: | 2022-06-22 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure-Guided Engineering of Prenyltransferase NphB for High-Yield and Regioselective Cannabinoid Production.
Acs Catalysis, 12, 2022
|
|
7FHC
 | | Structure of prenyltransferase mutant V49W from Streptomyces sp. (strain CL190) | | Descriptor: | Prenyltransferase | | Authors: | Xue, B, Lim, K.J.H, Hartono, Y.D, Go, M.D.K, Fan, H, Yew, W.S. | | Deposit date: | 2021-07-29 | | Release date: | 2022-06-22 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Structure-Guided Engineering of Prenyltransferase NphB for High-Yield and Regioselective Cannabinoid Production.
Acs Catalysis, 12, 2022
|
|
7FHB
 | | Structure of prenyltransferase from Streptomyces sp. (strain CL190) with bound GPP | | Descriptor: | GERANYL DIPHOSPHATE, Prenyltransferase | | Authors: | Xue, B, Lim, K.J.H, Hartono, Y.D, Go, M.D.K, Fan, H, Yew, W.S. | | Deposit date: | 2021-07-29 | | Release date: | 2022-06-22 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure-Guided Engineering of Prenyltransferase NphB for High-Yield and Regioselective Cannabinoid Production.
Acs Catalysis, 12, 2022
|
|
7FHD
 | | Structure of prenyltransferase mutant Y288P from Streptomyces sp. (strain CL190) | | Descriptor: | Prenyltransferase | | Authors: | Xue, B, Lim, K.J.H, Hartono, Y.D, Go, M.D.K, Fan, H, Yew, W.S. | | Deposit date: | 2021-07-29 | | Release date: | 2022-06-22 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structure-Guided Engineering of Prenyltransferase NphB for High-Yield and Regioselective Cannabinoid Production.
Acs Catalysis, 12, 2022
|
|
7FHF
 | | Structure of prenyltransferase mutant V49W/Y288F/Q295F from Streptomyces sp. (strain CL190) | | Descriptor: | Prenyltransferase | | Authors: | Xue, B, Lim, K.J.H, Hartono, Y.D, Go, M.D.K, Fan, H, Yew, W.S. | | Deposit date: | 2021-07-29 | | Release date: | 2022-06-22 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure-Guided Engineering of Prenyltransferase NphB for High-Yield and Regioselective Cannabinoid Production.
Acs Catalysis, 12, 2022
|
|
7CV3
 | | Quadruplex-duplex hybrid structure in the PIM1 gene, Form 1 | | Descriptor: | PIM1 promoter, Form 1 | | Authors: | Winnerdy, F.R, Tan, D.J.Y, Lim, K.W, Phan, A.T. | | Deposit date: | 2020-08-25 | | Release date: | 2020-10-07 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Coexistence of two quadruplex-duplex hybrids in the PIM1 gene.
Nucleic Acids Res., 48, 2020
|
|
7CLS
 | |
7CV4
 | | Quadruplex-duplex hybrid structure in the PIM1 gene, Form 2 | | Descriptor: | DNA (26-MER) | | Authors: | Winnerdy, F.R, Tan, D.T.J, Lim, K.W, Phan, A.T. | | Deposit date: | 2020-08-25 | | Release date: | 2020-10-07 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Coexistence of two quadruplex-duplex hybrids in the PIM1 gene.
Nucleic Acids Res., 48, 2020
|
|
7EUC
 | | Parallel G-quadruplex structure | | Descriptor: | DNA (5'-D(*TP*TP*GP*GP*GP*G)-3'), DNA (5'-D(P*GP*GP*GP*G)-3'), DNA (5'-D(P*GP*GP*GP*GP*T)-3'), ... | | Authors: | Winnerdy, F.R, Devi, G, Ang, J.C.Y, Lim, K.W, Phan, A.T. | | Deposit date: | 2021-05-17 | | Release date: | 2022-03-30 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Four-Layered Intramolecular Parallel G-Quadruplex with Non-Nucleotide Loops: An Ultra-Stable Self-Folded DNA Nano-Scaffold.
Acs Nano, 16, 2022
|
|
1NFD
 | | AN ALPHA-BETA T CELL RECEPTOR (TCR) HETERODIMER IN COMPLEX WITH AN ANTI-TCR FAB FRAGMENT DERIVED FROM A MITOGENIC ANTIBODY | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, H57 FAB, N15 ALPHA-BETA T-CELL RECEPTOR | | Authors: | Wang, J.-H, Lim, K, Smolyar, A, Teng, M.-K, Sacchittini, J, Reinherz, E.L. | | Deposit date: | 1997-08-04 | | Release date: | 1998-01-28 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Atomic structure of an alphabeta T cell receptor (TCR) heterodimer in complex with an anti-TCR fab fragment derived from a mitogenic antibody.
EMBO J., 17, 1998
|
|
1NNX
 | | Structure of the hypothetical protein ygiW from E. coli. | | Descriptor: | Protein ygiW, SULFATE ION | | Authors: | Lehmann, C, Galkin, A, Pullalarevu, S, Sarikaya, E, Krajewski, W, Lim, K, Howard, A, Herzberg, O, Structure 2 Function Project (S2F) | | Deposit date: | 2003-01-14 | | Release date: | 2004-03-09 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structure of the hypothetical protein ygiW from E. coli.
To be Published
|
|
1PKG
 | | Structure of a c-Kit Kinase Product Complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, c-kit protein | | Authors: | Mol, C.D, Lim, K.B, Sridhar, V, Zou, H, Chien, E.Y.T, Sang, B.-C, Nowakowski, J, Kassel, D.B, Cronin, C.N, McRee, D.E. | | Deposit date: | 2003-06-05 | | Release date: | 2003-08-12 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structure of a c-Kit Product Complex Reveals the Basis for Kinase Transactivation.
J.Biol.Chem., 278, 2003
|
|
1RXX
 | | Structure of arginine deiminase | | Descriptor: | Arginine deiminase | | Authors: | Galkin, A, Kulakova, L, Sarikaya, E, Lim, K, Howard, A, Herzberg, O, Structure 2 Function Project (S2F) | | Deposit date: | 2003-12-18 | | Release date: | 2004-01-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structural insight into arginine degradation by arginine deiminase, an antibacterial and parasite drug target.
J.Biol.Chem., 279, 2004
|
|
1JOE
 | | Crystal Structure of Autoinducer-2 Production Protein (LuxS) from Heamophilus influenzae | | Descriptor: | AUTOINDUCER-2 PRODUCTION PROTEIN, MERCURY (II) ION, ZINC ION | | Authors: | Chen, C.C.H, Parsons, J.F, Lim, K, Lehmann, C, Tempczyk, A, Eisenstein, E, Herzberg, O, Structure 2 Function Project (S2F) | | Deposit date: | 2001-07-27 | | Release date: | 2001-08-08 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | CRYSTAL STRUCTURE OF AUTOINDUCER-2 PRODUCTION PROTEIN (LUXS) FROM HEAMOPHILUS INFLUENZAE--A CASE OF TWINNED CRYSTAL
To be Published
|
|
