Structure of a two-G-tetrad basket-type intramolecular G-quadruplex formed by Giardia telomeric repeat d(TAGGG)4 in K+ solution (with G18-to-INO substitution)

Summary for 2KOW

Related2KF7 2KF8 2KM3
DescriptorDNA (5'-D(*TP*AP*GP*GP*GP*TP*AP*GP*GP*GP*TP*AP*GP*GP*GP*TP*AP*IP*GP*G)-3') (1 entity in total)
Functional Keywordstelomere, g-quadruplex, g.(a-g) triad, taggg repeat, dna, giardia
Total number of polymer chains1
Total molecular weight6360.1
Hu, L.,Lim, K.W.,Bouaziz, S.,Phan, A.T. (deposition date: 2009-10-02, release date: 2009-11-17, Last modification date: 2011-07-13)
Primary citation
Hu, L.,Lim, K.W.,Bouaziz, S.,Phan, A.T.
Giardia Telomeric Sequence d(TAGGG)(4) Forms Two Intramolecular G-Quadruplexes in K(+) Solution: Effect of Loop Length and Sequence on the Folding Topology.
J.Am.Chem.Soc., 131:16824-16831, 2009
PubMed: 19874015 (PDB entries with the same primary citation)
DOI: 10.1021/ja905611c
MImport into Mendeley
Experimental method

Structure validation

Clashscore20MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation reportDownload