6XD3
Structure of the human CAK in complex with THZ1
Summary for 6XD3
Entry DOI | 10.2210/pdb6xd3/pdb |
Related | 6XBZ |
EMDB information | 22123 22131 |
Descriptor | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... (4 entities in total) |
Functional Keywords | kinase, transcription, cell cycle, complex, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 87940.65 |
Authors | Greber, B.J.,Perez-Bertoldi, J.M.,Lim, K.,Iavarone, A.T.,Toso, D.B.,Nogales, E. (deposition date: 2020-06-09, release date: 2020-09-09, Last modification date: 2020-09-30) |
Primary citation | Greber, B.J.,Perez-Bertoldi, J.M.,Lim, K.,Iavarone, A.T.,Toso, D.B.,Nogales, E. The cryoelectron microscopy structure of the human CDK-activating kinase. Proc.Natl.Acad.Sci.USA, 117:22849-22857, 2020 Cited by PubMed: 32855301DOI: 10.1073/pnas.2009627117 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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