6VXJ
| Structure of ABCG2 bound to SN38 | Descriptor: | 7-ethyl-10-hydroxycamptothecin, Broad substrate specificity ATP-binding cassette transporter ABCG2, CHOLESTEROL | Authors: | Orlando, B.J, Liao, M. | Deposit date: | 2020-02-22 | Release date: | 2020-05-13 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | ABCG2 transports anticancer drugs via a closed-to-open switch. Nat Commun, 11, 2020
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6VXH
| Structure of ABCG2 bound to imatinib | Descriptor: | 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, Broad substrate specificity ATP-binding cassette transporter ABCG2, CHOLESTEROL | Authors: | Orlando, B.J, Liao, M. | Deposit date: | 2020-02-21 | Release date: | 2020-05-13 | Last modified: | 2024-10-23 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | ABCG2 transports anticancer drugs via a closed-to-open switch. Nat Commun, 11, 2020
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6VXI
| Structure of ABCG2 bound to mitoxantrone | Descriptor: | 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, Broad substrate specificity ATP-binding cassette transporter ABCG2, CHOLESTEROL | Authors: | Orlando, B.J, Liao, M. | Deposit date: | 2020-02-21 | Release date: | 2020-05-13 | Last modified: | 2020-05-20 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | ABCG2 transports anticancer drugs via a closed-to-open switch. Nat Commun, 11, 2020
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6NPH
| Structure of NKCC1 TM domain | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, POTASSIUM ION, ... | Authors: | Feng, L, Liao, M.F, Orlando, B, Zhang, J.R. | Deposit date: | 2019-01-17 | Release date: | 2019-07-31 | Last modified: | 2020-01-29 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure and mechanism of the cation-chloride cotransporter NKCC1. Nature, 572, 2019
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6VZ1
| Cryo-EM structure of human diacylglycerol O-acyltransferase 1 complexed with acyl-CoA substrate | Descriptor: | Diacylglycerol O-acyltransferase 1, S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (9Z)-octadec-9-enethioate (non-preferred name), [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | Authors: | Sui, X, Wang, K, Gluchowski, N, Liao, M, Walther, C.T, Farese Jr, V.R. | Deposit date: | 2020-02-27 | Release date: | 2020-05-13 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure and catalytic mechanism of a human triacylglycerol-synthesis enzyme. Nature, 581, 2020
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6NPL
| Cryo-EM structure of NKCC1 | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, POTASSIUM ION, ... | Authors: | Feng, L, Liao, M.F, Orlando, B, Zhang, J.R. | Deposit date: | 2019-01-17 | Release date: | 2019-07-31 | Last modified: | 2024-10-30 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure and mechanism of the cation-chloride cotransporter NKCC1. Nature, 572, 2019
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6NPK
| Structure of the TM domain | Descriptor: | Solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | Authors: | Feng, L, Liao, M.F, Orlando, B, Zhang, J.R. | Deposit date: | 2019-01-17 | Release date: | 2019-07-31 | Last modified: | 2024-10-23 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure and mechanism of the cation-chloride cotransporter NKCC1. Nature, 572, 2019
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6NPJ
| Structure of the NKCC1 CTD | Descriptor: | Sodium-potassium-chloride cotransporter 1 | Authors: | Feng, L, Liao, M.F, Orlando, B, Zhang, J.R. | Deposit date: | 2019-01-17 | Release date: | 2019-07-31 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure and mechanism of the cation-chloride cotransporter NKCC1. Nature, 572, 2019
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6CP6
| Monomer yeast ATP synthase (F1Fo) reconstituted in nanodisc. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase protein 8, ... | Authors: | Srivastava, A.P, Luo, M, Symersky, J, Liao, M.F, Mueller, D.M. | Deposit date: | 2018-03-13 | Release date: | 2018-04-11 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane. Science, 360, 2018
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6CP7
| Monomer yeast ATP synthase Fo reconstituted in nanodisc generated from masked refinement. | Descriptor: | ATP synthase protein 8, ATP synthase subunit 4, mitochondrial, ... | Authors: | Srivastava, A.P, Luo, M, Symersky, J, Liao, M.F, Mueller, D.M. | Deposit date: | 2018-03-13 | Release date: | 2018-04-11 | Last modified: | 2024-10-23 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane. Science, 360, 2018
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6CP5
| Monomer yeast ATP synthase Fo reconstituted in nanodisc with inhibitor of oligomycin bound generated from focused refinement. | Descriptor: | ATP synthase protein 8, ATP synthase subunit 4, mitochondrial, ... | Authors: | Srivastava, A.P, Luo, M, Symersky, J, Liao, M.F, Mueller, D.M. | Deposit date: | 2018-03-13 | Release date: | 2018-04-11 | Last modified: | 2024-10-23 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane. Science, 360, 2018
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6CP3
| Monomer yeast ATP synthase (F1Fo) reconstituted in nanodisc with inhibitor of oligomycin bound. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase protein 8, ... | Authors: | Srivastava, A.P, Luo, M, Symersky, J, Liao, M.F, Mueller, D.M. | Deposit date: | 2018-03-13 | Release date: | 2018-04-11 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane. Science, 360, 2018
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8XNT
| Respiratory complex Peripheral Arm of CI, close form C, focus-refined map of type IB, Wild type mouse under Cold Acclimation | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | Authors: | Shin, Y.-C, Liao, M. | Deposit date: | 2023-12-30 | Release date: | 2024-10-30 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural basis of respiratory complex adaptation to cold temperatures. Cell, 2024
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8XNY
| Respiratory complex Peripheral Arm of CI, open form B, focus-refined map of type II, Wild type mouse under Cold Acclimation | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | Authors: | Shin, Y.-C, Liao, M. | Deposit date: | 2023-12-30 | Release date: | 2024-10-30 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural basis of respiratory complex adaptation to cold temperatures. Cell, 2024
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5U0A
| CRISPR RNA-guided surveillance complex | Descriptor: | CRISPR-associated protein, Cas5e family, Cse1 family, ... | Authors: | Xiao, Y, Luo, M, Hayes, R.P, Kim, J, Ng, S, Ding, F, Liao, M, Ke, A. | Deposit date: | 2016-11-23 | Release date: | 2017-08-09 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System. Cell, 170, 2017
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8XNO
| Respiratory complex Peripheral Arm of CI, close form A, focus-refined map of type IA, Wild type mouse under Cold Acclimation | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | Authors: | Shin, Y.-C, Liao, M. | Deposit date: | 2023-12-30 | Release date: | 2024-10-30 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis of respiratory complex adaptation to cold temperatures. Cell, 2024
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5U07
| CRISPR RNA-guided surveillance complex | Descriptor: | CRISPR-associated protein, Cas5e family, Cse1 family, ... | Authors: | Xiao, Y, Luo, M, Hayes, R.P, Kim, J, Ng, S, Ding, F, Liao, M, Ke, A. | Deposit date: | 2016-11-23 | Release date: | 2017-08-09 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System. Cell, 170, 2017
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6NJ8
| Encapsulin iron storage compartment from Quasibacillus thermotolerans | Descriptor: | Encapsulating protein for a DyP-type peroxidase, targeting peptide | Authors: | Orlando, B.J, Giessen, T.W, Chambers, M.G, Liao, M, Silver, P.A. | Deposit date: | 2019-01-02 | Release date: | 2019-08-07 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.85 Å) | Cite: | Large protein organelles form a new iron sequestration system with high storage capacity. Elife, 8, 2019
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8XNN
| Respiratory complex Peripheral Arm of CI, open form A, focus-refined map of type I, Wild type mouse under thermoneutral temperature | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | Authors: | Shin, Y.-C, Liao, M. | Deposit date: | 2023-12-30 | Release date: | 2024-10-30 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis of respiratory complex adaptation to cold temperatures. Cell, 2024
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8XNM
| Respiratory complex Peripheral Arm of CI, close form B, focus-refined map of type I, Wild type mouse under thermoneutral temperature | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | Authors: | Shin, Y.-C, Liao, M. | Deposit date: | 2023-12-30 | Release date: | 2024-10-30 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of respiratory complex adaptation to cold temperatures. Cell, 2024
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8XNQ
| Respiratory complex Peripheral Arm of CI, open form A, focus-refined map of type IA, Wild type mouse under Cold Acclimation | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | Authors: | Shin, Y.-C, Liao, M. | Deposit date: | 2023-12-30 | Release date: | 2024-10-30 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural basis of respiratory complex adaptation to cold temperatures. Cell, 2024
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8XNX
| Respiratory complex Peripheral Arm of CI, open form A, focus-refined map of type II, Wild type mouse under Cold Acclimation | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | Authors: | Shin, Y.-C, Liao, M. | Deposit date: | 2023-12-30 | Release date: | 2024-10-30 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of respiratory complex adaptation to cold temperatures. Cell, 2024
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8XNL
| Respiratory complex Peripheral Arm of CI, close form A, focus-refined map of type I, Wild type mouse under thermoneutral temperature | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | Authors: | Shin, Y.-C, Liao, M. | Deposit date: | 2023-12-30 | Release date: | 2024-10-30 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of respiratory complex adaptation to cold temperatures. Cell, 2024
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8XNP
| Respiratory complex Peripheral Arm of CI, close form B, focus-refined map of type IA, Wild type mouse under Cold Acclimation | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | Authors: | Shin, Y.-C, Liao, M. | Deposit date: | 2023-12-30 | Release date: | 2024-10-30 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of respiratory complex adaptation to cold temperatures. Cell, 2024
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8XNS
| Respiratory complex Peripheral Arm of CI, close form B, focus-refined map of type IB, Wild type mouse under Cold Acclimation | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | Authors: | Shin, Y.-C, Liao, M. | Deposit date: | 2023-12-30 | Release date: | 2024-10-30 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of respiratory complex adaptation to cold temperatures. Cell, 2024
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