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PDB: 26 件
4RZK
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BU of 4rzk by Molmil
Crystal structure of Sulfolobus solfataricus Hsp20.1 ACD
分子名称: Small heat shock protein hsp20 family
著者Liang, L, Yun, C.H.
登録日2014-12-22
公開日2015-12-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.677 Å)
主引用文献Crystal structure and function of an unusual dimeric Hsp20.1 provide insight into the thermal protection mechanism of small heat shock proteins.
Biochem.Biophys.Res.Commun., 2015
5GWN
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BU of 5gwn by Molmil
Crystal structure of human RCC2
分子名称: Protein RCC2, SULFATE ION
著者Liang, L, Yun, C.H, Yin, Y.X.
登録日2016-09-12
公開日2017-09-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.309 Å)
主引用文献RCC2 is a novel p53 target in suppressing metastasis.
Oncogene, 37, 2018
3F7O
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BU of 3f7o by Molmil
Crystal structure of Cuticle-Degrading Protease from Paecilomyces lilacinus (PL646)
分子名称: (MSU)(ALA)(ALA)(PRO)(VAL), CALCIUM ION, Serine protease
著者Liang, L, Lou, Z, Meng, Z, Rao, Z, Zhang, K.
登録日2008-11-10
公開日2009-11-17
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The crystal structures of two cuticle-degrading proteases from nematophagous fungi and their contribution to infection against nematodes.
Faseb J., 24, 2010
4R94
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BU of 4r94 by Molmil
Structure of the nickase domain of NS1 from MVM complexed with magnesium
分子名称: MAGNESIUM ION, Non-structural protein NS1
著者Liang, L, Zhao, H, Tang, L.
登録日2014-09-03
公開日2015-01-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.668 Å)
主引用文献Structures of minute virus of mice replication initiator protein N-terminal domain: Insights into DNA nicking and origin binding.
Virology, 476C, 2014
5XDP
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BU of 5xdp by Molmil
K11/48-branched teraubiquitin
分子名称: D-ubiquitin, ubiquitin-B
著者Liang, L, Gao, S, Tang, S.
登録日2017-03-28
公開日2017-04-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.376 Å)
主引用文献K11/48-branched teraubiquitin
To Be Published
3F7M
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BU of 3f7m by Molmil
Crystal structure of apo Cuticle-Degrading Protease (ver112) from Verticillium psalliotae
分子名称: Alkaline serine protease ver112
著者Liang, L, Lou, Z, Ye, F, Meng, Z, Rao, Z, Zhang, K.
登録日2008-11-09
公開日2009-11-17
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The crystal structures of two cuticle-degrading proteases from nematophagous fungi and their contribution to infection against nematodes.
Faseb J., 24, 2010
6JOJ
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BU of 6joj by Molmil
Crystal structure of PDGFRA T674I in complex with crenolanib by soaking
分子名称: 1-(2-{5-[(3-Methyloxetan-3-yl)methoxy]-1H-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine, CHLORIDE ION, Platelet-derived growth factor receptor alpha, ...
著者Liang, L, Yan, X.E, Yun, C.H.
登録日2019-03-22
公開日2020-03-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of PDGFRA in complex with crenolanib by soaking
To Be Published
6JOK
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BU of 6jok by Molmil
Crystal structure of PDGFRA in complex with sunitinib by soaking
分子名称: CHLORIDE ION, N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide, Platelet-derived growth factor receptor alpha
著者Liang, L, Yan, X.E, Yun, C.H.
登録日2019-03-22
公開日2020-03-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Crystal structure of PDGFRA in complex with sunitinib by soaking
To Be Published
6JOL
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BU of 6jol by Molmil
Crystal structure of PDGFRA in complex with imatinib by co-crystallization
分子名称: 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, Platelet-derived growth factor receptor alpha
著者Liang, L, Yan, X.E, Yun, C.H.
登録日2019-03-22
公開日2020-03-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of PDGFRA in complex with imatinib by co-crystallization
To Be Published
6KTO
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BU of 6kto by Molmil
Crystal structure of human SHLD3-C-REV7-O-REV7-SHLD2 complex
分子名称: Mitotic spindle assembly checkpoint protein MAD2B, Shieldin complex subunit 2, Shieldin complex subunit 3
著者Liang, L, Yin, Y.
登録日2019-08-28
公開日2020-04-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.4497633 Å)
主引用文献Molecular basis for assembly of the shieldin complex and its implications for NHEJ.
Nat Commun, 11, 2020
6JOI
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BU of 6joi by Molmil
Crystal structure of PDGFRA T674I in complex with crenolanib by co-crystallization
分子名称: 1-(2-{5-[(3-Methyloxetan-3-yl)methoxy]-1H-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine, Platelet-derived growth factor receptor alpha
著者Liang, L, Yan, X.E, Yun, C.H.
登録日2019-03-22
公開日2020-03-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure of PDGFRA T674I in complex with crenolanib by co-crystallization
To Be Published
7WM2
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BU of 7wm2 by Molmil
Cryo-EM structure of AKT1
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium channel AKT1
著者Dongliang, L, Zijie, Z, Yannan, Q, Yuyue, T, Huaizong, S.
登録日2022-01-14
公開日2023-01-25
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.69 Å)
主引用文献Structural basis for the regulation mechanism of a hyperpolarization-activated K+ channel AKT1 by AtKC1
To Be Published
7WM1
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BU of 7wm1 by Molmil
Cryo-EM structure of AKT1-AtKC1
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium channel AKT1, ...
著者Dongliang, L, Zijie, Z, Yannan, Q, Yuyue, T, Huaizong, S.
登録日2022-01-14
公開日2023-01-25
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis for the regulation mechanism of a hyper polarization-activated K+ channel AKT1 by AtKC1
To Be Published
7MEY
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BU of 7mey by Molmil
Structure of yeast Ubr1 in complex with Ubc2 and monoubiquitinated N-degron
分子名称: 2-(ethylamino)ethane-1-thiol, E3 ubiquitin-protein ligase UBR1, Monoubiquitinated N-degron, ...
著者Pan, M, Zheng, Q, Wang, T, Liang, L, Yu, Y, Liu, L, Zhao, M.
登録日2021-04-08
公開日2021-11-24
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献Structural insights into Ubr1-mediated N-degron polyubiquitination.
Nature, 600, 2021
7MEX
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BU of 7mex by Molmil
Structure of yeast Ubr1 in complex with Ubc2 and N-degron
分子名称: E3 ubiquitin-protein ligase UBR1, N-degron, Ubiquitin, ...
著者Pan, M, Zheng, Q, Wang, T, Liang, L, Yu, Y, Liu, L, Zhao, M.
登録日2021-04-08
公開日2021-11-24
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Structural insights into Ubr1-mediated N-degron polyubiquitination.
Nature, 600, 2021
2MI7
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BU of 2mi7 by Molmil
Solution NMR structure of alpha3Y
分子名称: de novo protein a3Y
著者Glover, S.D, Jorge, C, Liang, L, Valentine, K.G, Hammarstrom, L, Tommos, C.
登録日2013-12-10
公開日2014-08-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Photochemical tyrosine oxidation in the structurally well-defined alpha 3Y protein: proton-coupled electron transfer and a long-lived tyrosine radical.
J.Am.Chem.Soc., 136, 2014
8JE2
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BU of 8je2 by Molmil
Cryo-EM structure of neddylated Cul2-Rbx1-EloBC-FEM1B complexed with FNIP1-FLCN
分子名称: Cullin-2, Elongin-B, Elongin-C, ...
著者Dai, Z, Liang, L, Yin, Y.X.
登録日2023-05-15
公開日2024-02-28
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.63 Å)
主引用文献Structural insights into the ubiquitylation strategy of the oligomeric CRL2 FEM1B E3 ubiquitin ligase.
Embo J., 43, 2024
8JE1
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BU of 8je1 by Molmil
An asymmetry dimer of the Cul2-Rbx1-EloBC-FEM1B ubiquitin ligase complexed with BEX2
分子名称: Cullin-2, E3 ubiquitin-protein ligase RBX1, Elongin-B, ...
著者Dai, Z, Liang, L, Yin, Y.X.
登録日2023-05-15
公開日2024-02-28
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.95 Å)
主引用文献Structural insights into the ubiquitylation strategy of the oligomeric CRL2 FEM1B E3 ubiquitin ligase.
Embo J., 43, 2024
5K5X
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BU of 5k5x by Molmil
Crystal structure of human PDGFRA
分子名称: Platelet-derived growth factor receptor alpha, SULFATE ION
著者Yan, X.E, Liang, L, Yun, C.H.
登録日2016-05-24
公開日2016-08-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.168 Å)
主引用文献Structural and biochemical studies of the PDGFRA kinase domain
Biochem.Biophys.Res.Commun., 477, 2016
2LXY
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BU of 2lxy by Molmil
NMR structure of 2-MERCAPTOPHENOL-ALPHA3C
分子名称: 2-MERCAPTOPHENOL, 2-mercaptophenol-alpha3C
著者Tommos, C, Valentine, K.G, Martinez-Rivera, M.C, Liang, L, Moorman, V.R.
登録日2012-09-06
公開日2013-02-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Reversible phenol oxidation and reduction in the structurally well-defined 2-Mercaptophenol-alpha(3)C protein.
Biochemistry, 52, 2013
4MQ1
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BU of 4mq1 by Molmil
The crystal structure of DYRK1a with a bound pyrido[2,3-d]pyrimidine inhibitor
分子名称: Dual specificity tyrosine-phosphorylation-regulated kinase 1A, N-(5-{[(1R)-3-amino-1-(3-chlorophenyl)propyl]carbamoyl}-2-chlorophenyl)-2-methoxy-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide, PENTAETHYLENE GLYCOL, ...
著者Lukacs, C.M, Janson, C.A, Garvie, C, Liang, L.
登録日2013-09-15
公開日2013-12-11
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Pyrido[2,3-d]pyrimidines: Discovery and preliminary SAR of a novel series of DYRK1B and DYRK1A inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
5VGT
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BU of 5vgt by Molmil
X-ray structure of bacteriophage Sf6 tail adaptor protein gp7
分子名称: CALCIUM ION, Gene 7 protein, MAGNESIUM ION
著者Tang, L, Liang, L, Zhao, H.
登録日2017-04-11
公開日2017-12-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.776 Å)
主引用文献High-resolution structure of podovirus tail adaptor suggests repositioning of an octad motif that mediates the sequential tail assembly.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8IJ1
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BU of 8ij1 by Molmil
Protomer 1 and 2 of the asymmetry trimer of the Cul2-Rbx1-EloBC-FEM1B ubiquitin ligase complex
分子名称: Cullin-2, E3 ubiquitin-protein ligase RBX1, Elongin-B, ...
著者Dai, Z, Liang, L, Yin, Y.X.
登録日2023-02-24
公開日2024-02-28
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural insights into the ubiquitylation strategy of the oligomeric CRL2 FEM1B E3 ubiquitin ligase.
Embo J., 43, 2024
6A32
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BU of 6a32 by Molmil
Crystal structure of PDGFRA kinase domain mutant T674I
分子名称: Platelet-derived growth factor receptor alpha
著者Yan, X.E, Liang, L, Yun, C.H.
登録日2018-06-14
公開日2019-06-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Crystal structure of PDGFRA kinase domain mutant T674I
To Be Published
6JBM
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BU of 6jbm by Molmil
Crystal structure of the TRIM14 PRYSPRY domain
分子名称: SULFATE ION, Tripartite motif-containing protein 14
著者Yin, Y.X, Yu, Y, Liang, L.
登録日2019-01-26
公開日2020-03-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The TRIM14 PRYSPRY domain mediates protein interaction via its basic interface.
Febs Lett., 593, 2019

 

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