6JOK

Crystal structure of PDGFRA in complex with sunitinib by soaking

Summary for 6JOK

• Entry DOI: 10.2210/pdb6jok/pdb
• Descriptor: Platelet-derived growth factor receptor alpha, N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: pdgfra, inhibitor, sunitinib, oncoprotein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 1
• Total formula weight: 41058.11

Authors

Liang, L.,Yan, X.E.,Yun, C.H. (deposition date: 2019-03-22, release date: 2020-03-25, Last modification date: 2023-11-22)

• Primary citation: Liang, L.,Yan, X.E.; Crystal structure of PDGFRA in complex with sunitinib by soaking; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.8 Å)