6JOJ

Crystal structure of PDGFRA T674I in complex with crenolanib by soaking

Summary for 6JOJ

• Entry DOI: 10.2210/pdb6joj/pdb
• Descriptor: Platelet-derived growth factor receptor alpha, 1-(2-{5-[(3-Methyloxetan-3-yl)methoxy]-1H-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine, SULFATE ION, ... (5 entities in total)
• Functional Keywords: pdgfra, inhibitor, crenolanib, oncoprotein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 1
• Total formula weight: 41472.57

Authors

Liang, L.,Yan, X.E.,Yun, C.H. (deposition date: 2019-03-22, release date: 2020-03-25, Last modification date: 2023-11-22)

• Primary citation: Liang, L.,Yan, X.E.; Crystal structure of PDGFRA in complex with crenolanib by soaking; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.6 Å)