Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 67 件
5YAO
DownloadVisualize
BU of 5yao by Molmil
The complex structure of SZ529 and expoxid
分子名称: (1R,5S)-6-oxabicyclo[3.1.0]hexane, Limonene-1,2-epoxide hydrolase, SODIUM ION
著者Lian, W, Sun, Z.T, Zhou, J.H, Reetz, M.T.
登録日2017-09-01
公開日2018-06-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.611 Å)
主引用文献Structural and Computational Insight into the Catalytic Mechanism of Limonene Epoxide Hydrolase Mutants in Stereoselective Transformations
J. Am. Chem. Soc., 140, 2018
5COR
DownloadVisualize
BU of 5cor by Molmil
X-RAY STRUCTURE OF MACROPHAGE INFLAMMATORY PROTEIN-1 ALPHA (CCL3) N-TERMINAL-SWITCH POLYMER
分子名称: ACETATE ION, C-C motif chemokine 3, HEXANE-1,6-DIOL
著者Liang, W.G, Tang, W.
登録日2015-07-20
公開日2016-04-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.548 Å)
主引用文献Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3.
Proc.Natl.Acad.Sci.USA, 113, 2016
5COY
DownloadVisualize
BU of 5coy by Molmil
Crystal structure of CC chemokine 5 (CCL5)
分子名称: C-C motif chemokine 5, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ...
著者Liang, W.G, Tang, W.
登録日2015-07-20
公開日2016-04-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.443 Å)
主引用文献Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3.
Proc.Natl.Acad.Sci.USA, 113, 2016
5CMD
DownloadVisualize
BU of 5cmd by Molmil
Oligomer crystal structure of CC chemokine 5 (CCL5)
分子名称: C-C motif chemokine 5, SULFATE ION
著者Liang, W.G, Tang, W.-J.
登録日2015-07-16
公開日2016-04-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.086 Å)
主引用文献Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3.
Proc.Natl.Acad.Sci.USA, 113, 2016
5CJO
DownloadVisualize
BU of 5cjo by Molmil
Crystal Structure Analysis of Elbow-Engineered-Fab-Bound Human Insulin Degrading Enzyme (IDE) in Complex with Insulin
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FAB Heavy chain with engineered elbow, FAB light chain, ...
著者liang, w.g, bailey, L, tang, w.j.
登録日2015-07-14
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.287 Å)
主引用文献Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination.
J. Mol. Biol., 2017
5UOE
DownloadVisualize
BU of 5uoe by Molmil
Crystal Structure Analysis of Elbow-Engineered-Fab-Bound Human Insulin Degrading Enzyme (IDE)
分子名称: FAB Heavy chain with engineered elbow, FAB light chain, Insulin-degrading enzyme
著者Liang, W.G, Bailey, L, Kossiakoff, T, Tang, W.J.
登録日2017-01-31
公開日2018-02-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Crystal Structure Analysis of Elbow-Engineered-Fab-Bound Human Insulin Degrading Enzyme (IDE)
To Be Published
6XOS
DownloadVisualize
BU of 6xos by Molmil
CryoEM structure of human presequence protease in partial open state 1
分子名称: Presequence protease, mitochondrial
著者Liang, W.G, Zhao, M, Tang, W.
登録日2020-07-07
公開日2021-07-07
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition.
Nat Commun, 13, 2022
6XOU
DownloadVisualize
BU of 6xou by Molmil
CryoEM structure of human presequence protease in open state
分子名称: Presequence protease, mitochondrial
著者Liang, W.G, Zhao, M, Tang, W.
登録日2020-07-07
公開日2021-07-07
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition.
Nat Commun, 13, 2022
6XOV
DownloadVisualize
BU of 6xov by Molmil
CryoEM structure of human presequence protease in partial closed state 1
分子名称: Amyloid-beta precursor protein, Presequence protease, mitochondrial
著者Liang, W.G, Zhao, M, Tang, W.
登録日2020-07-07
公開日2021-07-07
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition.
Nat Commun, 13, 2022
6XOW
DownloadVisualize
BU of 6xow by Molmil
CryoEM structure of human presequence protease in partial close state 2, induced by presequence of citrate synthase
分子名称: Presequence protease, mitochondrial
著者Liang, W.G, Tang, W.
登録日2020-07-07
公開日2021-07-07
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献CryoEM structure of human presequence protease in partial open state 2, induced by presequence of citrate synthase
To Be Published
6XOT
DownloadVisualize
BU of 6xot by Molmil
CryoEM structure of human presequence protease in partial open state 2
分子名称: Presequence protease, mitochondrial
著者Liang, W.G, Zhao, M, Tang, W.
登録日2020-07-07
公開日2021-07-07
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition.
Nat Commun, 13, 2022
6XLY
DownloadVisualize
BU of 6xly by Molmil
CRYOEM STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS ZINC METALLOPROTEASE ZMP1 IN OPEN STATE
分子名称: Probable zinc metalloprotease Zmp1, ZINC ION
著者Liang, W.G, Zhao, M, Tang, W.
登録日2020-06-29
公開日2020-12-23
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural analysis of Mycobacterium tuberculosis M13 metalloprotease Zmp1 open states.
Structure, 29, 2021
6B70
DownloadVisualize
BU of 6b70 by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain and insulin
分子名称: FAB H11-E heavy chain, FAB H11-E light chain, Insulin, ...
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-03
公開日2017-12-27
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6BF8
DownloadVisualize
BU of 6bf8 by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with insulin
分子名称: Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-26
公開日2018-04-04
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6B7Y
DownloadVisualize
BU of 6b7y by Molmil
Cryo-EM structure of human insulin degrading enzyme
分子名称: Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-05
公開日2017-11-08
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6BFC
DownloadVisualize
BU of 6bfc by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with insulin
分子名称: Insulin, Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-26
公開日2017-12-27
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6BF6
DownloadVisualize
BU of 6bf6 by Molmil
Cryo-EM structure of human insulin degrading enzyme
分子名称: Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-26
公開日2018-02-07
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6B3Q
DownloadVisualize
BU of 6b3q by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with insulin
分子名称: Insulin, Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-09-22
公開日2017-11-22
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6B7Z
DownloadVisualize
BU of 6b7z by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11 heavy chain and FAB H11 light chain
分子名称: FAB H11 heavy chain, FAB H11 light chain, Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-05
公開日2018-01-10
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6BF9
DownloadVisualize
BU of 6bf9 by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain
分子名称: Fab H11-E heavy chain, Fab H11-E light chain, Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-26
公開日2018-02-07
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (7.2 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6BF7
DownloadVisualize
BU of 6bf7 by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain
分子名称: Fab H11-E heavy chain, Fab H11-E light chain, Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-26
公開日2018-02-07
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
4RE9
DownloadVisualize
BU of 4re9 by Molmil
Crystal structure of human insulin degrading enzyme (IDE) in complex with compound 71290
分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-fluoro-N-({1-[(2R)-4-(hydroxyamino)-1-(naphthalen-2-yl)-4-oxobutan-2-yl]-1H-1,2,3-triazol-5-yl}methyl)benzamide, ...
著者Liang, W.G, Deprez, R, Deprez, B, Tang, W.J.
登録日2014-09-22
公開日2015-09-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.908 Å)
主引用文献Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice.
Nat Commun, 6, 2015
4RA8
DownloadVisualize
BU of 4ra8 by Molmil
Structure analysis of the Mip1a P8A mutant
分子名称: C-C motif chemokine 3
著者Liang, W.G, Ren, M, Guo, Q, Tang, W.J.
登録日2014-09-09
公開日2014-09-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme.
J.Mol.Biol., 427, 2015
4RAL
DownloadVisualize
BU of 4ral by Molmil
Crystal structure of insulin degrading enzyme in complex with macrophage inflammatory protein 1 beta
分子名称: C-C motif chemokine 4, Insulin-degrading enzyme, ZINC ION
著者Liang, W.G, Ren, M, Guo, Q, Tang, W.J.
登録日2014-09-10
公開日2015-05-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.148 Å)
主引用文献Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme.
J.Mol.Biol., 427, 2015
6C6D
DownloadVisualize
BU of 6c6d by Molmil
20mer crystal structure of CC chemokine 5 (CCL5)
分子名称: C-C motif chemokine 5
著者Liang, W.G, Tang, W.J.
登録日2018-01-18
公開日2019-01-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (5.5 Å)
主引用文献20mer crystal structure of CC chemokine 5 (CCL5)
To Be Published

 

123>

224004

件を2024-08-21に公開中

PDB statisticsPDBj update infoContact PDBjnumon