3B98
| Crystal structure of zebrafish prostacyclin synthase (cytochrome P450 8A1) | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, Prostaglandin I2 synthase | Authors: | Li, Y.-C, Chiang, C.-W, Yeh, H.-C, Hsu, P.-Y, Whitby, F.G, Wang, L.-H, Chan, N.-L. | Deposit date: | 2007-11-03 | Release date: | 2007-11-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Structures of Prostacyclin Synthase and Its Complexes with Substrate Analog and Inhibitor Reveal a Ligand-specific Heme Conformation Change J.Biol.Chem., 283, 2008
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3B6H
| Crystal structure of human prostacyclin synthase in complex with inhibitor minoxidil | Descriptor: | 6-PIPERIDIN-1-YLPYRIMIDINE-2,4-DIAMINE 3-OXIDE, PROTOPORPHYRIN IX CONTAINING FE, Prostacyclin synthase, ... | Authors: | Li, Y.-C, Chiang, C.-W, Yeh, H.-C, Hsu, P.-Y, Whitby, F.G, Wang, L.-H, Chan, N.-L. | Deposit date: | 2007-10-29 | Release date: | 2007-11-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Structures of Prostacyclin Synthase and Its Complexes with Substrate Analog and Inhibitor Reveal a Ligand-specific Heme Conformation Change J.Biol.Chem., 283, 2008
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8JOL
| cryo-EM structure of the CED-4/CED-3 holoenzyme | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cell death protein 3, Cell death protein 4, ... | Authors: | Li, Y, Tian, L, Zhang, Y, Shi, Y. | Deposit date: | 2023-06-07 | Release date: | 2023-06-28 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insights into CED-3 activation. Life Sci Alliance, 6, 2023
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5DO2
| Complex structure of MERS-RBD bound with 4C2 antibody | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4C2 heavy chain, 4C2 light chain, ... | Authors: | Li, Y, Wan, Y, Liu, P, Zhao, J, Lu, G, Qi, J, Wang, Q, Lu, X, Wu, Y, Liu, W, Yuen, K.Y, Perlman, S, Gao, G.F, Yan, J. | Deposit date: | 2015-09-10 | Release date: | 2015-10-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.409 Å) | Cite: | A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein. Cell Res., 25, 2015
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3FYH
| Recombinase in complex with ADP and metatungstate | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA repair and recombination protein radA, MAGNESIUM ION, ... | Authors: | Li, Y, He, Y, Luo, Y. | Deposit date: | 2009-01-22 | Release date: | 2009-09-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of an archaeal Rad51 homologue in complex with a metatungstate inhibitor. Biochemistry, 48, 2009
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7CYV
| Crystal structure of FD20, a neutralizing single-chain variable fragment (scFv) in complex with SARS-CoV-2 Spike receptor-binding domain (RBD) | Descriptor: | Spike protein S1, The heavy chain variable region of the scFv FD20,The light chain variable region of the scFv FD20, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Li, Y, Li, T, Lai, Y, Cai, H, Yao, H, Li, D. | Deposit date: | 2020-09-04 | Release date: | 2021-09-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.13 Å) | Cite: | Uncovering a conserved vulnerability site in SARS-CoV-2 by a human antibody. Embo Mol Med, 13, 2021
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3ETL
| RadA recombinase from Methanococcus maripaludis in complex with AMPPNP | Descriptor: | DNA repair and recombination protein radA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Li, Y, He, Y, Luo, Y. | Deposit date: | 2008-10-08 | Release date: | 2009-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Conservation of a conformational switch in RadA recombinase from Methanococcus maripaludis. Acta Crystallogr.,Sect.D, 65, 2009
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3EWA
| RADA recombinase from METHANOCOCCUS MARIPALUDIS in complex with AMPPNP and ammonium ions | Descriptor: | DNA repair and recombination protein radA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Li, Y, He, Y, Luo, Y. | Deposit date: | 2008-10-14 | Release date: | 2009-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Conservation of a conformational switch in RadA recombinase from Methanococcus maripaludis. Acta Crystallogr.,Sect.D, 65, 2009
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3EW9
| RADA recombinase from METHANOCOCCUS MARIPALUDIS in complex with AMPPNP and potassium ions | Descriptor: | DNA repair and recombination protein radA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Li, Y, He, Y, Luo, Y. | Deposit date: | 2008-10-14 | Release date: | 2009-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Conservation of a conformational switch in RadA recombinase from Methanococcus maripaludis. Acta Crystallogr.,Sect.D, 65, 2009
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4NHJ
| Crystal structure of Klebsiella pneumoniae RstA DNA-binding domain in complex with RstA box | Descriptor: | 5'-D(*CP*AP*GP*GP*GP*AP*GP*TP*AP*AP*CP*GP*GP*AP*AP*TP*GP*TP*AP*CP*AP*AP*C)-3', 5'-D(*GP*GP*TP*TP*GP*TP*AP*CP*AP*TP*TP*CP*CP*GP*TP*TP*AP*CP*TP*CP*CP*CP*T)-3', DNA-binding transcriptional regulator RstA | Authors: | Li, Y.C, Hsiao, C.D. | Deposit date: | 2013-11-05 | Release date: | 2014-07-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.701 Å) | Cite: | Structural dynamics of the two-component response regulator RstA in recognition of promoter DNA element. Nucleic Acids Res., 42, 2014
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3JBB
| Characterization of red-shifted phycobiliprotein complexes isolated from the chlorophyll f-containing cyanobacterium Halomicronema hongdechloris | Descriptor: | PHYCOCYANOBILIN, SULFATE ION, allophycocyanin beta chain, ... | Authors: | Li, Y, Lin, Y, Garvey, C, Birch, D, Corkery, R.W, Loughlin, P.C, Scheer, H, Willows, R.D, Chen, M. | Deposit date: | 2015-08-26 | Release date: | 2015-11-11 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (26 Å) | Cite: | Characterization of red-shifted phycobilisomes isolated from the chlorophyll f-containing cyanobacterium Halomicronema hongdechloris. Biochim.Biophys.Acta, 1857, 2015
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1KQL
| Crystal structure of the C-terminal region of striated muscle alpha-tropomyosin at 2.7 angstrom resolution | Descriptor: | Fusion Protein of and striated muscle alpha-tropomyosin and the GCN4 leucine zipper | Authors: | Li, Y, Mui, S, Brown, J.H, Strand, J, Reshetnikova, L, Tobacman, L.S, Cohen, C. | Deposit date: | 2002-01-07 | Release date: | 2002-05-29 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The crystal structure of the C-terminal fragment of striated-muscle alpha-tropomyosin reveals a key troponin T recognition site. Proc.Natl.Acad.Sci.USA, 99, 2002
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4NIC
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4YZE
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8J4I
| Unveiling the Role of Human Prohibitin 2 as a Mitochondrial Calcium Channel in Parkinson's Disease | Descriptor: | Prohibitin-2 | Authors: | Li, Y.Y, Fang, Y, Gao, Y.X, Ding, W, Yang, J, Liu, Y, Shen, B, Wang, J.F, Zhou, S. | Deposit date: | 2023-04-20 | Release date: | 2024-06-05 | Method: | SOLUTION NMR | Cite: | Human Prohibitin 2 is a Mitochondrial Ca2+-Selective Channel To Be Published
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4ZVV
| Lactate dehydrogenase A in complex with a trisubstituted piperidine-2,4-dione inhibitor GNE-140 | Descriptor: | (2~{R})-5-(2-chlorophenyl)sulfanyl-2-(4-morpholin-4-ylphenyl)-4-oxidanyl-2-thiophen-3-yl-1,3-dihydropyridin-6-one, L-lactate dehydrogenase A chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Li, Y, Chen, Z, Eigenbrot, C. | Deposit date: | 2015-05-18 | Release date: | 2016-05-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition. Nat.Chem.Biol., 12, 2016
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3D34
| Structure of the F-spondin domain of mindin | Descriptor: | CALCIUM ION, NICKEL (II) ION, Spondin-2 | Authors: | Li, Y, Mariuzza, R.A. | Deposit date: | 2008-05-09 | Release date: | 2009-02-17 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of the F-spondin domain of mindin, an integrin ligand and pattern recognition molecule. Embo J., 28, 2009
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5ZN9
| Crystal structure of PX domain | Descriptor: | SULFATE ION, Sorting nexin-27 | Authors: | Li, Y, Zhu, Z, Li, F, Liao, S, Xu, C. | Deposit date: | 2018-04-08 | Release date: | 2019-04-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.776 Å) | Cite: | Crystal structure of PX domain To Be Published
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4P5B
| Crystal structure of a UMP/dUMP methylase PolB from Streptomyces cacaoi bound with 5-Br dUMP | Descriptor: | 5-BROMO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ... | Authors: | Li, Y, Chen, W, Li, J, Xia, Z, Deng, Z, Zhou, J. | Deposit date: | 2014-03-15 | Release date: | 2015-12-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.274 Å) | Cite: | Crystal structure of a UMP/dUMP methylase PolB form Streptomyces cacaoi bound with 5-Br dUMP To Be Published
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3HHS
| Crystal Structure of Manduca sexta prophenoloxidase | Descriptor: | COPPER (II) ION, Phenoloxidase subunit 1, Phenoloxidase subunit 2 | Authors: | Li, Y, Wang, Y, Jiang, H, Deng, J. | Deposit date: | 2009-05-17 | Release date: | 2009-09-29 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Crystal structure of Manduca sexta prophenoloxidase provides insights into the mechanism of type 3 copper enzymes. Proc.Natl.Acad.Sci.USA, 106, 2009
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8GJY
| Structure of a cGAS-like receptor Sp-cGLR1 from S. pistillata | Descriptor: | cGAS-like receptor 1 | Authors: | Li, Y, Toyoda, H, Slavik, K.M, Morehouse, B.R, Kranzusch, P.J. | Deposit date: | 2023-03-16 | Release date: | 2023-07-05 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | cGLRs are a diverse family of pattern recognition receptors in innate immunity. Cell, 186, 2023
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4P5A
| Crystal structure of a UMP/dUMP methylase PolB from Streptomyces cacaoi bound with 5-Br UMP | Descriptor: | 5-BROMO-URIDINE-5'-MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, Thymidylate synthase ThyX | Authors: | Li, Y, Chen, W, Li, J, Xia, Z, Deng, Z, Zhou, J. | Deposit date: | 2014-03-15 | Release date: | 2015-12-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Crystal structure of a UMP/dUMP methylase PolB from Streptomyces cacaoi with 5-Br UMP To Be Published
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1KGD
| Crystal Structure of the Guanylate Kinase-like Domain of Human CASK | Descriptor: | FORMIC ACID, PERIPHERAL PLASMA MEMBRANE CASK | Authors: | Li, Y, Spangenberg, O, Paarmann, I, Konrad, M, Lavie, A. | Deposit date: | 2001-11-26 | Release date: | 2001-12-19 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.314 Å) | Cite: | Structural basis for nucleotide-dependent regulation of membrane-associated guanylate kinase-like domains. J.Biol.Chem., 277, 2002
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8K80
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6M62
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