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PDB: 373 件

3VYN
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Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase LdtMt2 N55 truncation mutant (resideus 55-408)
分子名称: Probable conserved lipoprotein LPPS
著者Li, W.J, Li, D.F, Bi, L.J, Wang, D.C.
登録日2012-09-30
公開日2013-06-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of L,D-transpeptidase LdtMt2 in complex with meropenem reveals the mechanism of carbapenem against Mycobacterium tuberculosis
Cell Res., 23, 2013
3VYP
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Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase LdtMt2-N140 adduct with meropenem
分子名称: (2S,3R,4S)-4-{[(3S,5R)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, GLYCEROL, Probable conserved lipoprotein LPPS
著者Li, W.J, Li, D.F, Bi, L.J, Wang, D.C.
登録日2012-09-30
公開日2013-06-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of L,D-transpeptidase LdtMt2 in complex with meropenem reveals the mechanism of carbapenem against Mycobacterium tuberculosis
Cell Res., 23, 2013
6OM7
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BU of 6om7 by Molmil
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-18
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OLE
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BU of 6ole by Molmil
Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-16
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
8HUX
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BU of 8hux by Molmil
Crystal structure of SARS-Cov-2 main protease P132H mutant in complex with S217622
分子名称: 3C-like proteinase nsp5, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione
著者Li, W.W, Zhang, J, Li, J.
登録日2022-12-24
公開日2023-06-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural basis for the inhibition of coronaviral main proteases by ensitrelvir.
Structure, 31, 2023
5ZJK
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BU of 5zjk by Molmil
Structure of myroilysin
分子名称: Myroilysin, PHOSPHATE ION, ZINC ION
著者Li, W.D, Ran, T.T, Xu, D.Q, Wang, W.W.
登録日2018-03-20
公開日2019-03-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of mature myroilysin and implication for its activation mechanism.
Int.J.Biol.Macromol., 2019
8IGB
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BU of 8igb by Molmil
Crystal structure of SARS-Cov-2 main protease P132H mutant in complex with GC376
分子名称: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
著者Li, W.W, Zhang, J, Li, J.
登録日2023-02-20
公開日2024-03-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8AOZ
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BU of 8aoz by Molmil
ForT Mutant L24A
分子名称: 1,2-ETHANEDIOL, 4-azanyl-3-[(2~{S},3~{R},4~{S},5~{R})-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]-1~{H}-pyrazole-5-carboxylic acid, Beta-ribofuranosylaminobenzene 5'-phosphate synthase, ...
著者Li, W, Naismith, J.H.
登録日2022-08-09
公開日2022-09-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Experimental and computational snapshots of C-C bond formation in a C-nucleoside synthase.
Open Biology, 13, 2023
8AP0
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BU of 8ap0 by Molmil
ForT Mutant T138V
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 4-azanyl-1~{H}-pyrazole-3,5-dicarboxylic acid, Beta-ribofuranosylaminobenzene 5'-phosphate synthase, ...
著者Li, W, Naismith, J.H.
登録日2022-08-09
公開日2022-09-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Experimental and computational snapshots of C-C bond formation in a C-nucleoside synthase.
Open Biology, 13, 2023
4LGI
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BU of 4lgi by Molmil
N-terminal truncated NleC structure
分子名称: Uncharacterized protein
著者Li, W.Q, Liu, Y.X, Sheng, X.L, Yan, C.Y, Wang, J.W.
登録日2013-06-28
公開日2014-01-15
最終更新日2015-02-25
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Structure and mechanism of a type III secretion protease, NleC
Acta Crystallogr.,Sect.D, 70, 2014
4LGJ
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BU of 4lgj by Molmil
Crystal structure and mechanism of a type III secretion protease
分子名称: Uncharacterized protein, ZINC ION
著者Li, W.Q, Liu, Y.X, Sheng, X.L, Yan, C.Y, Wang, J.W.
登録日2013-06-28
公開日2014-01-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure and mechanism of a type III secretion protease, NleC
Acta Crystallogr.,Sect.D, 70, 2014
6OLF
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BU of 6olf by Molmil
Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-16
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
3J9Z
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BU of 3j9z by Molmil
Activation of GTP Hydrolysis in mRNA-tRNA Translocation by Elongation Factor G
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Li, W, Liu, Z, Koripella, R.K, Langlois, R, Sanyal, S, Frank, J.
登録日2015-03-27
公開日2015-07-01
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G.
Sci Adv, 1, 2015
6OLI
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BU of 6oli by Molmil
Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-16
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OM0
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BU of 6om0 by Molmil
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-17
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
3JA1
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BU of 3ja1 by Molmil
Activation of GTP Hydrolysis in mRNA-tRNA Translocation by Elongation Factor G
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Li, W, Liu, Z, Koripella, R.K, Langlois, R, Sanyal, S, Frank, J.
登録日2015-03-30
公開日2015-07-01
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G.
Sci Adv, 1, 2015
4D3Z
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BU of 4d3z by Molmil
The structure of inactive prolegumain from chinese hamster, trigonal space group.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PROLEGUMAIN
著者Li, W, Heinz, D.W, Krausze, J.
登録日2014-10-24
公開日2016-01-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A Detailed Look Into Chinese Hamster Legumain Active Site Structure and Exploration of its Function
To be Published
4D3X
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BU of 4d3x by Molmil
The structure of mature legumain from chinese hamster.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, LEGUMAIN
著者Li, W, Heinz, D.W, Krausze, J.
登録日2014-10-24
公開日2016-01-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.848 Å)
主引用文献A Detailed Look Into Chinese Hamster Legumain Active Site Structure and Exploration of its Function
To be Published
4D3Y
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BU of 4d3y by Molmil
The structure of inactive prolegumain from chinese hamster.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, LEGUMAIN
著者Li, W, Heinz, D.W, Krausze, J.
登録日2014-10-24
公開日2016-01-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A Detailed Look Into Chinese Hamster Legumain Active Site Structure and Exploration of its Function
To be Published
6V9T
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BU of 6v9t by Molmil
Tudor domain of TDRD3 in complex with a small molecule
分子名称: 4-methyl-2,3,4,5,6,7-hexahydrodicyclopenta[b,e]pyridin-8(1H)-imine, Tudor domain-containing protein 3, UNKNOWN ATOM OR ION
著者Li, W, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2019-12-16
公開日2019-12-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.154 Å)
主引用文献A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II.
Nat Commun, 13, 2022
2YXR
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BU of 2yxr by Molmil
The plug domain of the SecY protein stablizes the closed state of the translocation channel and maintains a membrane seal
分子名称: Preprotein translocase secG subunit, Preprotein translocase subunit secE, Preprotein translocase subunit secY
著者Li, W, Schulman, S.
登録日2007-04-27
公開日2007-08-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献The plug domain of the SecY protein stabilizes the closed state of the translocation channel and maintains a membrane seal
Mol.Cell, 26, 2007
2YXQ
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BU of 2yxq by Molmil
The plug domain of the SecY protein stablizes the closed state of the translocation channel and maintains a membrane seal
分子名称: Preprotein translocase secG subunit, Preprotein translocase subunit secE, Preprotein translocase subunit secY
著者Li, W, Schulman, S.
登録日2007-04-27
公開日2007-08-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献The plug domain of the SecY protein stabilizes the closed state of the translocation channel and maintains a membrane seal
Mol.Cell, 26, 2007
1ZR2
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BU of 1zr2 by Molmil
Structure of a Synaptic gamma-delta Resolvase Tetramer Covalently Linked to two Cleaved DNAs
分子名称: AAA, TCAGTGTCCGATAATTTAT, TTATCGGACACTG, ...
著者Li, W, Kamtekar, S, Xiong, Y, Sarkis, G.J, Grindley, N.D, Steitz, T.A.
登録日2005-05-18
公開日2005-08-30
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Structure of a synaptic gamma delta resolvase tetramer covalently linked to two cleaved DNAs.
Science, 309, 2005
4ET0
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BU of 4et0 by Molmil
Crystal structure of circularly permuted human asparaginase-like protein 1
分子名称: L-asparaginase, SODIUM ION
著者Li, W.Z, Yogesha, S.D, Zhang, Y.
登録日2012-04-23
公開日2012-09-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Uncoupling Intramolecular Processing and Substrate Hydrolysis in the N-Terminal Nucleophile Hydrolase hASRGL1 by Circular Permutation.
Acs Chem.Biol., 7, 2012
3B9F
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BU of 3b9f by Molmil
1.6 A structure of the PCI-thrombin-heparin complex
分子名称: 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, GLYCEROL, Plasma serine protease inhibitor, ...
著者Li, W, Adams, T.E, Huntington, J.A.
登録日2007-11-05
公開日2008-04-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Molecular basis of thrombin recognition by protein C inhibitor revealed by the 1.6-A structure of the heparin-bridged complex.
Proc.Natl.Acad.Sci.Usa, 105, 2008

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