Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 157 results

4LEY
DownloadVisualize
BU of 4ley by Molmil
Structure of mouse cGAS bound to 18 bp DNA
Descriptor: 18 bp dsDNA, Cyclic GMP-AMP synthase, ZINC ION
Authors:Li, P.
Deposit date:2013-06-26
Release date:2013-12-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization.
Immunity, 39, 2013
3GA3
DownloadVisualize
BU of 3ga3 by Molmil
Crystal structure of the C-terminal domain of human MDA5
Descriptor: Interferon-induced helicase C domain-containing protein 1, MDA5, ZINC ION
Authors:Li, P.
Deposit date:2009-02-16
Release date:2009-02-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal structure of the C-terminal domain of human MDA5
To be Published
2OTU
DownloadVisualize
BU of 2otu by Molmil
Crystal structure of Fv polyglutamine complex
Descriptor: Fv heavy chain variable domain, Fv light chain variable domain, peptide antigen
Authors:Li, P.
Deposit date:2007-02-09
Release date:2007-04-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Implications of the structure of a poly-Gln/anti-poly-Gln complex for disease progression and therapy
To be Published
7EOD
DownloadVisualize
BU of 7eod by Molmil
MITF HLHLZ Delta AKE
Descriptor: GLYCEROL, Isoform M1 of Microphthalmia-associated transcription factor
Authors:Li, P, Liu, Z, Fang, P, Wang, J.
Deposit date:2021-04-22
Release date:2022-04-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy.
Cell Res., 33, 2023
5JEJ
DownloadVisualize
BU of 5jej by Molmil
Phosphorylated STING in complex with IRF-3 CTD
Descriptor: Interferon regulatory factor 3, Stimulator of interferon genes protein
Authors:Li, P, Shu, C.
Deposit date:2016-04-18
Release date:2016-06-15
Last modified:2016-06-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins.
Proc.Natl.Acad.Sci.USA, 113, 2016
5X1T
DownloadVisualize
BU of 5x1t by Molmil
PpkA-294
Descriptor: ADENOSINE-5'-DIPHOSPHATE, PpkA-294
Authors:Li, P.P, Ran, T.T, Xu, D.Q, Wang, W.W.
Deposit date:2017-01-26
Release date:2018-01-31
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structures of the kinase domain of PpkA, a key regulatory component of T6SS, reveal a general inhibitory mechanism.
Biochem.J., 475, 2018
5X1Q
DownloadVisualize
BU of 5x1q by Molmil
PpkA-294 with ATP and MnCl2
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MANGANESE (II) ION, ...
Authors:Li, P.P, Ran, T.T, Xu, D.Q, Wang, W.W.
Deposit date:2017-01-26
Release date:2018-01-31
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.602 Å)
Cite:Crystal structures of the kinase domain of PpkA, a key regulatory component of T6SS, reveal a general inhibitory mechanism.
Biochem.J., 475, 2018
5X1S
DownloadVisualize
BU of 5x1s by Molmil
PpkA-294 with Amppcp
Descriptor: GLYCEROL, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, PpkA
Authors:Li, P.P, Ran, T.T, Xu, D.Q, Wang, W.W.
Deposit date:2017-01-26
Release date:2018-01-31
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal structures of the kinase domain of PpkA, a key regulatory component of T6SS, reveal a general inhibitory mechanism.
Biochem.J., 475, 2018
5X1R
DownloadVisualize
BU of 5x1r by Molmil
PpkA-294 apo form
Descriptor: PpkA-294
Authors:Li, P.P, Ran, T.T, Xu, D.Q, Wang, W.W.
Deposit date:2017-01-26
Release date:2018-01-31
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures of the kinase domain of PpkA, a key regulatory component of T6SS, reveal a general inhibitory mechanism.
Biochem.J., 475, 2018
1N1A
DownloadVisualize
BU of 1n1a by Molmil
Crystal Structure of the N-terminal domain of human FKBP52
Descriptor: FKBP52
Authors:Li, P, Ding, Y, Wu, B, Shu, C, Shen, B, Rao, Z.
Deposit date:2002-10-16
Release date:2002-12-30
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the N-terminal domain of human FKBP52.
Acta Crystallogr.,Sect.D, 59, 2003
2OTW
DownloadVisualize
BU of 2otw by Molmil
Crystal structure of Fv polyglutamine complex
Descriptor: Fv heavy chain variable domain VH, Fv light chain avriable domain VL, poly-Gln peptide antigen
Authors:Li, P.
Deposit date:2007-02-09
Release date:2007-04-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Implications of the structure of a poly-Gln/anti-poly-Gln complex for disease progression and therapy
To be Published
1JFM
DownloadVisualize
BU of 1jfm by Molmil
CRYSTAL STRUCTURE OF MURINE NK CELL LIGAND RAE-1 BETA
Descriptor: retinoic acid early transcript beta
Authors:Li, P, Strong, R.K.
Deposit date:2001-06-21
Release date:2002-02-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal structures of RAE-1beta and its complex with the activating immunoreceptor NKG2D.
Immunity, 16, 2002
3LRN
DownloadVisualize
BU of 3lrn by Molmil
Crystal structure of human RIG-I CTD bound to a 14 bp GC 5' ppp dsRNA
Descriptor: Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*(GTP)P*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3'), ZINC ION
Authors:Li, P.
Deposit date:2010-02-11
Release date:2010-06-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Structural Basis of 5' Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain.
Structure, 18, 2010
4LEW
DownloadVisualize
BU of 4lew by Molmil
Structure of human cGAS
Descriptor: Cyclic GMP-AMP synthase, ZINC ION
Authors:Li, P.
Deposit date:2013-06-26
Release date:2013-12-25
Last modified:2014-01-08
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization.
Immunity, 39, 2013
5WSO
DownloadVisualize
BU of 5wso by Molmil
crystal structure of BVDV NS3 helicase
Descriptor: NS3 helicase
Authors:Li, P, Shi, J, Wang, S, Li, S, Mao, X.
Deposit date:2016-12-08
Release date:2017-12-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Crystal structure of BVDV NS3 helicase
To Be Published
4LEV
DownloadVisualize
BU of 4lev by Molmil
Structure of human cGAS
Descriptor: Cyclic GMP-AMP synthase, ZINC ION
Authors:Li, P.
Deposit date:2013-06-26
Release date:2013-12-25
Last modified:2014-01-08
Method:X-RAY DIFFRACTION (1.952 Å)
Cite:Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization.
Immunity, 39, 2013
3E3H
DownloadVisualize
BU of 3e3h by Molmil
Crystal structure of the OP hydrolase mutant from Brevundimonas diminuta
Descriptor: COBALT (II) ION, DIETHYL 4-METHYLBENZYLPHOSPHONATE, Parathion hydrolase
Authors:Li, P, Reeves, T.E, Grimsley, J.K, Wild, J.R.
Deposit date:2008-08-07
Release date:2008-10-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Balancing the stability and the catalytic specificities of OP hydrolases with enhanced V-agent activities.
Protein Eng.Des.Sel., 21, 2008
3OG8
DownloadVisualize
BU of 3og8 by Molmil
Crystal structure of human RIG-I CTD bound to a 14-bp blunt-ended dsRNA
Descriptor: Antiviral innate immune response receptor RIG-I, RNA (5'-R(*GP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3'), ZINC ION
Authors:Li, P.
Deposit date:2010-08-16
Release date:2010-11-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of RIG-I C-terminal domain bound to blunt-ended double-strand RNA without 5' triphosphate.
Nucleic Acids Res., 39, 2011
5V5F
DownloadVisualize
BU of 5v5f by Molmil
Crystal structure of RICE1 (PNT2)
Descriptor: At3g11770
Authors:Li, P.
Deposit date:2017-03-14
Release date:2017-09-13
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.945 Å)
Cite:RISC-interacting clearing 3'- 5' exoribonucleases (RICEs) degrade uridylated cleavage fragments to maintain functional RISC in Arabidopsis thaliana.
Elife, 6, 2017
4PP8
DownloadVisualize
BU of 4pp8 by Molmil
Crystal structure of murine NK cell ligand RAE-1 beta in complex with NKG2D
Descriptor: GLYCEROL, NKG2-D type II integral membrane protein, Retinoic acid early-inducible protein 1-beta
Authors:Li, P, Strong, R.K.
Deposit date:2014-02-26
Release date:2014-04-09
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structures of RAE-1beta and its complex with the activating immunoreceptor NKG2D.
Immunity, 16, 2002
3S2X
DownloadVisualize
BU of 3s2x by Molmil
Structure of acetyl-Coenzyme A synthase Alpha subunit C-terminal domain
Descriptor: NICKEL (II) ION, acetyl-CoA synthase subunit alpha
Authors:Li, P.
Deposit date:2011-05-17
Release date:2011-07-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Insights into the Mechanistic Role of the [Fe(4) S(4) ] Cubane in the A-Cluster {[Fe(4) S(4) ]-(SR)-[Ni(p) Ni(d) ]} of Acetyl-Coenzyme A Synthase.
Chembiochem, 12, 2011
3U9M
DownloadVisualize
BU of 3u9m by Molmil
Structure of reduced human FBXL5 hemerythrin like domain
Descriptor: F-box/LRR-repeat protein 5, FE (III) ION
Authors:Li, P.
Deposit date:2011-10-19
Release date:2012-02-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The Structural Basis of Iron Sensing by the Human F-box Protein FBXL5.
Chembiochem, 13, 2012
4EMT
DownloadVisualize
BU of 4emt by Molmil
Crystal Structure of human STING bound to c-di-GMP
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, Transmembrane protein 173
Authors:Li, P.
Deposit date:2012-04-12
Release date:2012-06-13
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system.
Nat.Struct.Mol.Biol., 19, 2012
4EMU
DownloadVisualize
BU of 4emu by Molmil
Crystal structure of ligand free human STING
Descriptor: CALCIUM ION, Transmembrane protein 173
Authors:Li, P.
Deposit date:2012-04-12
Release date:2012-06-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system.
Nat.Struct.Mol.Biol., 19, 2012
7JFM
DownloadVisualize
BU of 7jfm by Molmil
Crystal structure of mouse phosphorylated IRF-3 bound to CBP
Descriptor: CREB-binding protein, Interferon regulatory factor 3
Authors:Li, P, Jing, T, Zhao, B.
Deposit date:2020-07-17
Release date:2020-09-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:The Structural Basis of IRF-3 Activation upon Phosphorylation.
J Immunol., 205, 2020

224004

건을2024-08-21부터공개중

PDB statisticsPDBj update infoContact PDBjnumon