4LEV
Structure of human cGAS
Summary for 4LEV
Entry DOI | 10.2210/pdb4lev/pdb |
Related | 4LEW 4LEy 4LEz |
Descriptor | Cyclic GMP-AMP synthase, ZINC ION (3 entities in total) |
Functional Keywords | ntase, dna sensor, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytosol: Q8N884 |
Total number of polymer chains | 2 |
Total formula weight | 86897.19 |
Authors | |
Primary citation | Li, X.,Shu, C.,Yi, G.,Chaton, C.T.,Shelton, C.L.,Diao, J.,Zuo, X.,Kao, C.C.,Herr, A.B.,Li, P. Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization. Immunity, 39:1019-1031, 2013 Cited by PubMed: 24332030DOI: 10.1016/j.immuni.2013.10.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.952 Å) |
Structure validation
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